Search Results - "Go, Y"

Redox compartmentalization and cellular stress by Jones, D.P, Go, Y.-M

“…Mammalian cells are highly organized to optimize function. For instance, oxidative energy-producing processes in mitochondria are sequestered away from plasma…”
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CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer by Gao, Shanshan, Soares, Fraser, Wang, Shiyan, Wong, Chi Chun, Chen, Huarong, Yang, Zhenjie, Liu, Weixin, Go, Minnie Y. Y., Ahmed, Musaddeque, Zeng, Yong, O’Brien, Catherine Adell, Sung, Joseph J. Y., He, Housheng Hansen, Yu, Jun

“…Cancer stem cells (CSCs) are responsible for tumor progression, recurrence, and drug resistance. To identify genetic vulnerabilities of colon cancer, we…”
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Outcomes in refractory diffuse large B-cell lymphoma: results from the international SCHOLAR-1 study by Crump, Michael, Neelapu, Sattva S., Farooq, Umar, Van Den Neste, Eric, Kuruvilla, John, Westin, Jason, Link, Brian K., Hay, Annette, Cerhan, James R., Zhu, Liting, Boussetta, Sami, Feng, Lei, Maurer, Matthew J., Navale, Lynn, Wiezorek, Jeff, Go, William Y., Gisselbrecht, Christian

“…Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma. Although 5-year survival rates in the first-line setting range from…”
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Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity by Long, Xiaohang, Wong, Chi Chun, Tong, Li, Chu, Eagle S. H., Ho Szeto, Chun, Go, Minne Y. Y., Coker, Olabisi Oluwabukola, Chan, Anthony W. H., Chan, Francis K. L., Sung, Joseph J. Y., Yu, Jun

“…Emerging evidence implicates a role of the gut microbiota in colorectal cancer (CRC). Peptostreptococcus anaerobius ( P. anaerobius ) is an anaerobic bacterium…”
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Tumor burden, inflammation, and product attributes determine outcomes of axicabtagene ciloleucel in large B-cell lymphoma by Locke, Frederick L., Rossi, John M., Neelapu, Sattva S., Jacobson, Caron A., Miklos, David B., Ghobadi, Armin, Oluwole, Olalekan O., Reagan, Patrick M., Lekakis, Lazaros J., Lin, Yi, Sherman, Marika, Better, Marc, Go, William Y., Wiezorek, Jeffrey S., Xue, Allen, Bot, Adrian

“…ZUMA-1 demonstrated a high rate of durable response and a manageable safety profile with axicabtagene ciloleucel (axi-cel), an anti-CD19 chimeric antigen…”
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Evidence-based guideline update: Medical treatment of infantile spasms: Report of the Guideline Development Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society by GO, C. Y, MACKAY, M. T, WEISS, S. K, STEPHENS, D, ADAMS-WEBBER, T, ASHWAL, S, SNEAD, O. C

“…To update the 2004 American Academy of Neurology/Child Neurology Society practice parameter on treatment of infantile spasms in children. MEDLINE and EMBASE…”
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PEAK: A Randomized, Multicenter Phase II Study of Panitumumab Plus Modified Fluorouracil, Leucovorin, and Oxaliplatin (mFOLFOX6) or Bevacizumab Plus mFOLFOX6 in Patients With Previously Untreated, Unresectable, Wild-Type KRAS Exon 2 Metastatic Colorectal Cancer by SCHWARTZBERG, Lee S, RIVERA, Fernando, KARTHAUS, Meinolf, FASOLA, Gianpiero, CANON, Jean-Luc, HECHT, J. Randolph, HUA YU, OLINER, Kelly S, GO, William Y

“…To evaluate panitumumab plus modified fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) or bevacizumab plus mFOLFOX6 in patients with previously untreated…”
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Focal resection of fast ripples on extraoperative intracranial EEG improves seizure outcome in pediatric epilepsy by Akiyama, Tomoyuki, McCoy, Bláthnaid, Go, Cristina Y., Ochi, Ayako, Elliott, Irene M., Akiyama, Mari, Donner, Elizabeth J., Weiss, Shelly K., Snead, O. Carter, Rutka, James T., Drake, James M., Otsubo, Hiroshi

“…Summary Purpose:  High‐frequency oscillations (HFOs), termed ripples at 80–200 Hz and fast ripples (FRs) at >200/250 Hz, recorded by intracranial…”
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Zinc-finger protein 331, a novel putative tumor suppressor, suppresses growth and invasiveness of gastric cancer by Yu, J, Liang, Q Y, Wang, J, Cheng, Y, Wang, S, Poon, T C W, Go, M Y Y, Tao, Q, Chang, Z, Sung, J J Y

“…Zinc-finger protein 331 ( ZNF331 ), a Kruppel-associated box zinc-finger protein gene, was identified as a putative tumor suppressor in our previous study…”
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Similar Numbers but Different Repertoires of Olfactory Receptor Genes in Humans and Chimpanzees by Go, Yasuhiro, Niimura, Yoshihito

“…Animals recognize their external world through the detection of tens of thousands of chemical odorants. Olfactory receptor (OR) genes encode proteins for…”
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Transthoracic Ultrasound Imaging of the Descending Thoracic Aorta: Could We, Should We, and Would We? by Go, Y.Y., Lancellotti, P.

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A route to high surface area, porosity and inclusion of large molecules in crystals by O'Keeffe, Michael, Yaghi, Omar M, Chae, Hee K, Siberio-Pérez, Diana Y, Kim, Jaheon, Go, YongBok, Eddaoudi, Mohamed, Matzger, Adam J

“…One of the outstanding challenges in the field of porous materials is the design and synthesis of chemical structures with exceptionally high surface areas…”
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The LuxS/AI-2 Quorum-Sensing System of Streptococcus pneumoniae Is Required to Cause Disease, and to Regulate Virulence- and Metabolism-Related Genes in a Rat Model of Middle Ear Infection by Yadav, Mukesh K, Vidal, Jorge E, Go, Yoon Y, Kim, Shin H, Chae, Sung-Won, Song, Jae-Jun

“…colonizes the nasopharynx of children, and from nasopharynx it could migrate to the middle ear and causes acute otitis media (AOM). During colonization and…”
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Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial by Locke, Frederick L, Ghobadi, Armin, Jacobson, Caron A, Miklos, David B, Lekakis, Lazaros J, Oluwole, Olalekan O, Lin, Yi, Braunschweig, Ira, Hill, Brian T, Timmerman, John M, Deol, Abhinav, Reagan, Patrick M, Stiff, Patrick, Flinn, Ian W, Farooq, Umar, Goy, Andre, McSweeney, Peter A, Munoz, Javier, Siddiqi, Tanya, Chavez, Julio C, Herrera, Alex F, Bartlett, Nancy L, Wiezorek, Jeffrey S, Navale, Lynn, Xue, Allen, Jiang, Yizhou, Bot, Adrian, Rossi, John M, Kim, Jenny J, Go, William Y, Neelapu, Sattva S

“…Axicabtagene ciloleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. In the previous analysis of the ZUMA-1 registrational study,…”
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Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro by Wang, Jia, Zhao, Jingmin, Chu, Eagle SH, Mok, Myth TS, Go, Minnie YY, Man, Kwan, Heuchel, Rainer, Lan, Hui Yao, Chang, Zhijie, Sung, Joseph JY, Yu, Jun

“…Smad7 is a principal inhibitor of the TGFβ–Smad signalling pathway. We have investigated the functional significance of Smad7 in hepatocellular carcinoma…”
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NFAT5/TonEBP Mutant Mice Define Osmotic Stress as a Critical Feature of the Lymphoid Microenvironment by Go, William Y., Liu, Xuebin, Roti, Michelle A., Liu, Forrest, Ho, Steffan N., Glimcher, Laurie H.

“…Osmotic stress responses are critical not only to the survival of unicellular organisms but also to the normal function of the mammalian kidney. However, the…”
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Cancer T-cell therapy: building the foundation for a cure [version 2; peer review: 3 approved] by Kamb, Alexander, Go, William Y

“…T-cell cancer therapy is a clinical field flush with opportunity.  It is part of the revolution in immuno-oncology, most apparent in the dramatic clinical…”
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Antimicrobial and Antibiofilm Effects of Human Amniotic/Chorionic Membrane Extract on Streptococcus pneumoniae by Yadav, Mukesh K, Go, Yoon Y, Kim, Shin Hye, Chae, Sung-Won, Song, Jae-Jun

“…colonize the human nasopharynx in the form of biofilms. The biofilms act as bacterial reservoirs and planktonic bacteria from these biofilms can migrate to…”
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Cancer T-cell therapy: building the foundation for a cure [version 1; peer review: 1 approved, 2 approved with reservations] by Kamb, Alexander, Go, William Y

“…T-cell cancer therapy is a clinical field flush with opportunity.  It is part of the revolution in immuno-oncology, most apparent in the dramatic clinical…”
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Fibroblast growth factor 21 analogue LY2405319 lowers blood glucose in streptozotocin-induced insulin-deficient diabetic mice by restoring brown adipose tissue function by Kim, J.-H., Bae, K.-H., Choi, Y.-K., Go, Y., Choe, M., Jeon, Y.-H., Lee, H.-W., Koo, S.-H., Perfield II, J. W., Harris, R. A., Lee, I.-K., Park, K.-G.

“…Aim To investigate the effects of LY2405319, an analogue of fibroblast growth factor 21 (FGF21), on glucose homeostasis in streptozotocin (STZ)‐induced…”
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