Search Results - "Go, Maybelle K"

Increasing lysergic acid levels for ergot alkaloid biosynthesis: Directing catalysis via the F-G loop of Clavine oxidases by Lim, Li Rong, Wong, Garrett, Go, Maybelle K, Yew, Wen Shan

“…Most ergot alkaloid drugs are semi-synthetically derived from the natural product lysergic acid, a valuable precursor for the development of novel ergot…”
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Exploiting the Biosynthetic Potential of Type III Polyketide Synthases by Lim, Yan Ping, Go, Maybelle K, Yew, Wen Shan

“…Polyketides are structurally and functionally diverse secondary metabolites that are biosynthesized by polyketide synthases (PKSs) using acyl-CoA precursors…”
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Biosynthesis of Nature-Inspired Unnatural Cannabinoids by Lim, Kevin J H, Lim, Yan Ping, Hartono, Yossa D, Go, Maybelle K, Fan, Hao, Yew, Wen Shan

“…Natural products make up a large proportion of medicine available today. Cannabinoids from the plant is one unique class of meroterpenoids that have shown a…”
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A high-throughput pipeline for scalable kit-free RNA extraction by Han, Ping, Go, Maybelle K., Chow, Jeng Yeong, Xue, Bo, Lim, Yan Ping, Crone, Michael A., Storch, Marko, Freemont, Paul S., Yew, Wen Shan

“…An overreliance on commercial, kit-based RNA extraction in the molecular diagnoses of infectious disease presents a challenge in the event of supply chain…”
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Synthetic Enzymology and the Fountain of Youth: Repurposing Biology for Longevity by Lim, Yan Ping, Go, Maybelle K, Raida, Manfred, Inoue, Takao, Wenk, Markus R, Keasling, Jay D, Chang, Matthew W, Yew, Wen Shan

“…Caloric restriction (CR) is an intervention that can increase maximal lifespan in organisms, but its application to humans remains challenging. A more feasible…”
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Role of Lys-12 in Catalysis by Triosephosphate Isomerase: A Two-Part Substrate Approach by Go, Maybelle K, Koudelka, Astrid, Amyes, Tina L, Richard, John P

“…We report that the K12G mutation in triosephosphate isomerase (TIM) from Saccharomyces cerevisiae results in (1) a ∼50-fold increase in K m for the substrate…”
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Hydron Transfer Catalyzed by Triosephosphate Isomerase. Products of the Direct and Phosphite-Activated Isomerization of [1-13C]-Glycolaldehyde in D2O by Go, Maybelle K, Amyes, Tina L, Richard, John P

“…Product distributions for the reaction of glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-13C]-GA) catalyzed by triosephosphate isomerase…”
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Rescue of K12G Triosephosphate Isomerase by Ammonium Cations: The Reaction of an Enzyme in Pieces by Go, Maybelle K, Amyes, Tina L, Richard, John P

“…The K12G mutation at yeast triosephosphate isomerase (TIM) results in a 5.5 × 105-fold decrease in k cat/K m for isomerization of glyceraldehyde 3-phosphate,…”
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Enzyme Architecture: The Effect of Replacement and Deletion Mutations of Loop 6 on Catalysis by Triosephosphate Isomerase by Zhai, Xiang, Go, Maybelle K, O’Donoghue, AnnMarie C, Amyes, Tina L, Pegan, Scott D, Wang, Yan, Loria, J. Patrick, Mesecar, Andrew D, Richard, John P

“…Two mutations of the phosphodianion gripper loop in chicken muscle triosephosphate isomerase (cTIM) were examined: (1) the loop deletion mutant (LDM) formed by…”
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Wildtype and Engineered Monomeric Triosephosphate Isomerase from Trypanosoma brucei: Partitioning of Reaction Intermediates in D2O and Activation by Phosphite Dianion by Malabanan, M. Merced, Go, Maybelle K, Amyes, Tina L, Richard, John P

“…Product yields for the reactions of (R)-glyceraldehyde 3-phosphate (GAP) in D2O at pD 7.9 catalyzed by wildtype triosephosphate isomerase from Trypanosoma…”
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Bovine Serum Albumin-Catalyzed Deprotonation of [1-13C]Glycolaldehyde: Protein Reactivity toward Deprotonation of the α-Hydroxy α-Carbonyl Carbon by Go, Maybelle K, Malabanan, M. Merced, Amyes, Tina L, Richard, John P

“…Bovine serum albumin (BSA) in D2O at 25 °C and pD 7.0 was found to catalyze the deuterium exchange reactions of [1-13C]glycolaldehyde ([1-13C]GA) to form…”
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Alanine-dependent reactions of 5′-deoxypyridoxal in water by Go, Maybelle K., Richard, John P.

“…Alanine-catalyzed dimerization of pyridoxal in water. The non-enzymatic reaction of 5′-deoxypyridoxal (DPL) with l-alanine in water at 25 °C was investigated…”
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Wildtype and Engineered Monomeric Triosephosphate Isomerase from Trypanosoma brucei : Partitioning of Reaction Intermediates in D 2 O and Activation by Phosphite Dianion by Malabanan, M. Merced, Go, Maybelle K., Amyes, Tina L., Richard, John P.

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Hydron Transfer Catalyzed by Triosephosphate Isomerase. Products of the Direct and Phosphite-Activated Isomerization of [1- 13 C]-Glycolaldehyde in D 2 O by Go, Maybelle K., Amyes, Tina L., Richard, John P.

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Hydron transfer catalyzed by triosephosphate isomerase. Products of the direct and phosphite-activated isomerization of [1-(13)C]-glycolaldehyde in D(2)O by Go, Maybelle K, Amyes, Tina L, Richard, John P

“…Product distributions for the reaction of glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-(13)C]-GA) catalyzed by triosephosphate isomerase…”
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Studies on enzymatic and non-enzymatic proton transfer in aqueous solutions by Go, Maybelle Darlene K

“…The following proton transfer systems in aqueous solutions were studied. The non-enzymatic reaction of 5’-deoxypyridoxal with L-alanine was investigated. DPL…”
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Studies on enzymatic and non-enzymatic proton transfer in aqueous solutions by Go, Maybelle Darlene K

“…The following proton transfer systems in aqueous solutions were studied. The non-enzymatic reaction of 5'-deoxypyridoxal with L-alanine was investigated. DPL…”
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