Search Results - "Go, M J"
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Genetic variations in ATP2B1, CSK, ARSG and CSMD1 loci are related to blood pressure and/or hypertension in two Korean cohorts
Published in Journal of human hypertension (01-06-2010)“…Blood pressure, one of the important vital signs, is affected by multiple genetic and environmental factors. Recently, several genome-wide association (GWA)…”
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Genetic variations in the leptin and leptin receptor genes are associated with type 2 diabetes mellitus and metabolic traits in the Korean female population
Published in Clinical genetics (01-08-2008)“…Type 2 diabetes mellitus (T2DM) is a metabolic disorder that is characterized by insulin resistance and hyperglycemia. Leptin inhibits the glucose‐stimulated…”
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3
Association of TWIST1 gene polymorphisms with bone mineral density in postmenopausal women
Published in Osteoporosis international (01-05-2010)“…Summary A novel polymorphism (+1871A>G) in the 3′ flanking region and haplotypes were significantly associated with reduced osteoporosis risk and enhanced bone…”
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4
Non-synonymous single-nucleotide polymorphisms associated with blood pressure and hypertension
Published in Journal of human hypertension (01-11-2010)“…In this study, we determined the association of 1180 non-synonymous single-nucleotide polymorphisms (SNPs) with systolic blood pressure (SBP) and hypertensive…”
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5
Finite element prediction of proximal femoral fracture patterns under different loads
Published in Journal of biomechanical engineering (01-02-2005)“…The main purpose of this work is to discuss the ability of finite element analyses, together with an appropriate anisotropic fracture criterion, to predict the…”
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6
Cell proliferation control by Notch signaling in Drosophila development
Published in Development (Cambridge) (01-06-1998)“…The Notch receptor mediates cell interactions controlling the developmental fate of a broad spectrum of undifferentiated cells. By modulating Notch signaling…”
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7
Notch Signaling and the Determination of Appendage Identity
Published in Proceedings of the National Academy of Sciences - PNAS (29-02-2000)“…The Notch signaling pathway defines an evolutionarily conserved cell-cell interaction mechanism that throughout development controls the ability of precursor…”
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8
Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration
Published in The New England journal of medicine (16-03-2017)“…A goal of regenerative medicine is to use induced pluripotent stem cells to generate an autologous graft for transplantation. This study tests the feasibility…”
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9
Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements
Published in Development (Cambridge) (01-11-1997)“…The Notch (N) pathway defines an evolutionarily conserved cell signaling mechanism that governs cell fate choices through local cell interactions. The ankyrin…”
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10
Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats
Published in Development (Cambridge) (01-08-1995)“…We present a molecular and genetic analysis which elucidates the role of deltex in the Notch signaling pathway. Using the yeast âinteraction trapâ assay,…”
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11
A genetic screen for novel components of the Notch signaling pathway during drosophila bristle development
Published in Genetics (Austin) (01-09-1998)“…The Notch receptor is the central element in a cell signaling mechanism controlling a broad spectrum of cell fate choices. Genetic modifier screens in…”
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12
The genetic architecture of type 2 diabetes
Published in Nature (London) (04-08-2016)“…The genetic architecture of common traits, including the number, frequency, and effect sizes of inherited variants that contribute to individual risk, has been…”
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13
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
Published in PLoS medicine (12-09-2017)“…Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association…”
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14
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
Published in Nature genetics (01-03-2014)“…Andrew Morris, Mark McCarthy, Michael Boehnke and colleagues report a meta-analysis of genome-wide association studies for type 2 diabetes, including 26,488…”
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15
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Published in Nature (London) (06-10-2011)“…Genetic influence on blood pressure Compared to other common complex diseases, it has proved remarkably difficult to establish the genetic basis of…”
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16
Biological, clinical and population relevance of 95 loci for blood lipids
Published in Nature (London) (05-08-2010)“…Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most…”
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Developmental changes in phosphorylation state of neurofilament proteins in the chick embryonic optic nerve
Published in Developmental biology (01-07-1989)“…Developmental changes in the phosphorylation state of neurofilament proteins (NFPs) in the chick embryonic optic nerve were histochemically and biochemically…”
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18
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders
Published in Nature genetics (01-06-2013)“…Ruth Loos and colleagues report a meta-analysis of genome-wide association studies in 181,171 individuals identifying 14 new loci associated with heart rate…”
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Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations
Published in Nature genetics (01-08-2012)“…Yukinori Okada and colleagues report a meta-analysis of genome-wide association studies for kidney function–related traits in 71,149 individuals from east…”
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Monoclonal antibodies which stain small subsets of neurons in the Drosophila central nervous system
Published in Brain research. Developmental brain research (21-08-1992)“…Monoclonal antibodies (MAbs) specific to small subsets of neurons in the central nervous system (CNS) of Drosophila melanogaster were described. MAbs 43A8,…”
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