Search Results - "Go, Bok Soon"
-
1
Recapitulating phenotypes of alcohol dependence via overexpression of Oprk1 in the ventral tegmental area of non-dependent TH::Cre rats
Published in Neuropharmacology (01-05-2023)“…The dynorphin (DYN)/kappa-opioid receptor (KOR) system is involved in dysphoria and negative emotional states. Dysregulation of KOR function promotes…”
Get full text
Journal Article -
2
Repeated nicotine exposure increases the intracellular interaction between ERK‐mGluR5 in the nucleus accumbens more in adult than adolescent rats
Published in Addiction biology (01-03-2021)“…Intracellular interactions between protein kinases and metabotropic receptors in the striatum regulate behavioral changes in response to drug exposure. We…”
Get full text
Journal Article -
3
Role of Dopamine D2 Receptor in the Leptin Receptor‐expressing Neurons in Modulation of Compulsive‐like Eating Behavior
Published in The FASEB journal (01-04-2020)“…Abstract only…”
Get full text
Journal Article -
4
Psychostimulant-Induced Endoplasmic Reticulum Stress and Neurodegeneration
Published in Molecular neurobiology (01-08-2017)“…The endoplasmic reticulum (ER) is a subcellular organelle that ensures proper protein folding process. The ER stress is defined as cellular conditions that…”
Get full text
Journal Article -
5
Glutamatergic neurotransmission in the prefrontal cortex mediates the suppressive effect of intra-prelimbic cortical infusion of BDNF on cocaine-seeking
Published in European neuropsychopharmacology (01-12-2016)“…Abstract Cocaine self-administration induces dysfunctional neuroadaptations in the prefrontal cortex that underlie relapse to cocaine-seeking. Cocaine…”
Get full text
Journal Article -
6
The role of matrix metalloproteinase‐9 in negative reinforcement learning and plasticity in alcohol dependence
Published in Addiction biology (01-03-2020)“…A role for matrix metalloproteinases (MMPs) in plasticity‐dependent learning has been established. MMPs degrade the extracellular matrix (ECM) when synaptic…”
Get full text
Journal Article -
7
Kappa-opioid receptor antagonism in the nucleus accumbens shell distinguishes escalated alcohol consumption and negative affective-like behavior from physiological withdrawal in alcohol-dependence
Published in Pharmacology, biochemistry and behavior (01-10-2024)“…Alcohol use disorder (AUD) is a chronic relapsing disease that is deleterious at individual, familial, and societal levels. Although AUD is one of the highest…”
Get full text
Journal Article -
8
Glutamine has antidepressive effects through increments of glutamate and glutamine levels and glutamatergic activity in the medial prefrontal cortex
Published in Neuropharmacology (01-12-2018)“…Emerging evidence has shown the low levels of glutamate (Glu) and glutamine (Gln) and the hypoactivity in the cortex of patients with depression. The…”
Get full text
Journal Article -
9
Activation of c-Jun N-terminal kinase is required for the regulation of endoplasmic reticulum stress response in the rat dorsal striatum following repeated cocaine administration
Published in Neuropharmacology (01-07-2010)“…Repeated exposure to cocaine upregulates endoplasmic reticulum (ER) stress response and c-Jun N-terminal kinase (JNK) phosphorylation is associated with the ER…”
Get full text
Journal Article -
10
Linking cocaine to endoplasmic reticulum in striatal neurons: Role of glutamate receptors
Published in Basal ganglia (01-07-2011)“…The endoplasmic reticulum (ER) controls protein folding. Accumulation of unfolded and misfolded proteins in the ER triggers an ER stress response to accelerate…”
Get full text
Journal Article