Search Results - "Gnjatic, S."

CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens by Almeida, Luiz Gonzaga, Sakabe, Noboru J, deOliveira, Alice R, Silva, Maria Cristina C, Mundstein, Alex S, Cohen, Tzeela, Chen, Yao-Tseng, Chua, Ramon, Gurung, Sita, Gnjatic, Sacha, Jungbluth, Achim A, Caballero, Otávia L, Bairoch, Amos, Kiesler, Eva, White, Sarah L, Simpson, Andrew J.G, Old, Lloyd J, Camargo, Anamaria A, Vasconcelos, Ana Tereza R

“…The potency of the immune response has still to be harnessed effectively to combat human cancers. However, the discovery of T-cell targets in melanomas and…”
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Vaccination of stage III/IV melanoma patients with long NY-ESO-1 peptide and CpG-B elicits robust CD8+ and CD4+ T-cell responses with multiple specificities including a novel DR7-restricted epitope by Baumgaertner, P., Costa Nunes, C., Cachot, A., Maby-El Hajjami, H., Cagnon, L., Braun, M., Derré, L., Rivals, J.-P., Rimoldi, D., Gnjatic, S., Abed Maillard, S., Marcos Mondéjar, P., Protti, M. P., Romano, E., Michielin, O., Romero, P., Speiser, D. E., Jandus, C.

“…Long synthetic peptides and CpG-containing oligodeoxynucleotides are promising components for cancer vaccines. In this phase I trial, 19 patients received a…”
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Immune response, safety, and overall survival of NY-ESO-1+ soft tissue sarcoma patients treated with CMB305 therapy by Chawla, S.P., Pollack, S., Block, M., Druta, M., Do, K., Morris, J.C., Kim, J.W., Bohac, C., Lu, H., Gnjatic, S., Jones, R.L., Hwu, P., Somaiah, N.

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NY-ESO-1 is associated with an aggressive phenotype of ovarian cancer by Szender, J.B, Papanicolau-Sengos, A, Eng, K, Miliotto, A.J, Lugade, A, Gnjatic, S, Matsuzaki, J, Odunsi, K

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Improving the efficacy of cancer immunotherapy by Copier, J, Dalgleish, A.G, Britten, C.M, Finke, L.H, Gaudernack, G, Gnjatic, S, Kallen, K, Kiessling, R, Schuessler-Lenz, M, Singh, H, Talmadge, J, Zwierzina, H, Håkansson, L

“…Abstract A series of cancer vaccines have been evaluated in clinical trials with encouraging results, but the demonstration of clinical benefit in confirmatory…”
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Recombinant MAGE-A3 protein immunotherapy and peripheral blood lymphocyte (PBL) reconstitution induce strong antigen-specific humoral and cellular immune responses in patients undergoing autologous stem cell transplantation (ASCT) for consolidation of multiple myeloma (MM) by Lendvai, N, Cohen, A.D, Gnjatic, S, Jungbluth, A.A, Bertolini, S, Pan, L, Venhaus, R, Tsakos, I, Garcia, K, Thibodeau, L, Alpaugh, K, Cummings, N, Lehmann, F.F, Gruselle, O, Cho, H.J

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Cancer-testis antigen expression and immunogenicity in AL amyloidosis by Rosenzweig, M A, Landau, H, Seldin, D, O'Hara, C, Girnius, S, Hanson, N, Frosina, D, Sedrak, C, Arcila, M, Comenzo, R L, Giralt, S, Gnjatic, S, Jungbluth, A A, Koehne, G

“…Light-chain amyloidosis (AL) is a plasma cell dyscrasia closely related to multiple myeloma. In multiple myeloma, the cancer-testis antigens (CTAs) CT7…”
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Single-cell immune landscape of human atherosclerotic plaques by Fernandez, Dawn M., Rahman, Adeeb H., Fernandez, Nicolas F., Chudnovskiy, Aleksey, Amir, El-ad David, Amadori, Letizia, Khan, Nayaab S., Wong, Christine K., Shamailova, Roza, Hill, Christopher A., Wang, Zichen, Remark, Romain, Li, Jennifer R., Pina, Christian, Faries, Christopher, Awad, Ahmed J., Moss, Noah, Bjorkegren, Johan L. M., Kim-Schulze, Seunghee, Gnjatic, Sacha, Ma’ayan, Avi, Mocco, J, Faries, Peter, Merad, Miriam, Giannarelli, Chiara

“…Atherosclerosis is driven by multifaceted contributions of the immune system within the circulation and at vascular focal sites. However, specific…”
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Classification of current anticancer immunotherapies by Galluzzi, Lorenzo, Vacchelli, Erika, Bravo-San Pedro, José-Manuel, Buqué, Aitziber, Senovilla, Laura, Baracco, Elisa Elena, Bloy, Norma, Castoldi, Francesca, Abastado, Jean-Pierre, Agostinis, Patrizia, Apte, Ron N., Aranda, Fernando, Ayyoub, Maha, Beckhove, Philipp, Blay, Jean-Yves, Bracci, Laura, Caignard, Anne, Castelli, Chiara, Cavallo, Federica, Celis, Estaban, Cerundolo, Vincenzo, Clayton, Aled, Colombo, Mario P., Coussens, Lisa, Dhodapkar, Madhav V., Eggermont, Alexander M., Fearon, Douglas T., Fridman, Wolf H., Fučíková, Jitka, Gabrilovich, Dmitry I., Galon, Jérôme, Garg, Abhishek, Ghiringhelli, François, Giaccone, Giuseppe, Gilboa, Eli, Gnjatic, Sacha, Hoos, Axel, Hosmalin, Anne, Jäger, Dirk, Kalinski, Pawel, Kärre, Klas, Kepp, Oliver, Kiessling, Rolf, Kirkwood, John M., Klein, Eva, Knuth, Alexander, Lewis, Claire E., Liblau, Roland, Lotze, Michael T., Lugli, Enrico, Mach, Jean-Pierre, Mattei, Fabrizio, Mavilio, Domenico, Melero, Ignacio, Melief, Cornelis J., Mittendorf, Elizabeth A., Moretta, Lorenzo, Odunsi, Adekunke, Okada, Hideho, Palucka, Anna Karolina, Peter, Marcus E., Pienta, Kenneth J., Porgador, Angel, Prendergast, George C., Rabinovich, Gabriel A., Restifo, Nicholas P., Rizvi, Naiyer, Sautès-Fridman, Catherine, Schreiber, Hans, Seliger, Barbara, Shiku, Hiroshi, Silva-Santos, Bruno, Smyth, Mark J., Speiser, Daniel E., Spisek, Radek, Srivastava, Pramod K., Talmadge, James E., Tartour, Eric, Van Der Burg, Sjoerd H., Van Den Eynde, Benoît J., Vile, Richard, Wagner, Hermann, Weber, Jeffrey S, Whiteside, Theresa L., Wolchok, Jedd D., Zitvogel, Laurence, Zou, Weiping, Kroemer, Guido

“…© 2014. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution,…”
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Tumor antigen NY-CO-58/KIF2C is strongly overexpressed in a variety of human cancers and evokes spontaneous T cell responses by Atanackovic, D, Cao, Y, Hildebrandt, Y, Bartels, K, Horn, C, Stahl, T, Old, L.J, Gnjatic, S, Bokemeyer, C

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Cancer classification using the Immunoscore: a worldwide task force by Galon, Jérôme, Pagès, Franck, Marincola, Francesco M, Angell, Helen K, Thurin, Magdalena, Lugli, Alessandro, Zlobec, Inti, Berger, Anne, Bifulco, Carlo, Botti, Gerardo, Tatangelo, Fabiana, Britten, Cedrik M, Kreiter, Sebastian, Chouchane, Lotfi, Delrio, Paolo, Arndt, Hartmann, Asslaber, Martin, Maio, Michele, Masucci, Giuseppe V, Mihm, Martin, Vidal-Vanaclocha, Fernando, Allison, James P, Gnjatic, Sacha, Hakansson, Leif, Huber, Christoph, Singh-Jasuja, Harpreet, Ottensmeier, Christian, Zwierzina, Heinz, Laghi, Luigi, Grizzi, Fabio, Ohashi, Pamela S, Shaw, Patricia A, Clarke, Blaise A, Wouters, Bradly G, Kawakami, Yutaka, Hazama, Shoichi, Okuno, Kiyotaka, Wang, Ena, O'Donnell-Tormey, Jill, Lagorce, Christine, Pawelec, Graham, Nishimura, Michael I, Hawkins, Robert, Lapointe, Réjean, Lundqvist, Andreas, Khleif, Samir N, Ogino, Shuji, Gibbs, Peter, Waring, Paul, Sato, Noriyuki, Torigoe, Toshihiko, Itoh, Kyogo, Patel, Prabhu S, Shukla, Shilin N, Palmqvist, Richard, Nagtegaal, Iris D, Wang, Yili, D'Arrigo, Corrado, Kopetz, Scott, Sinicrope, Frank A, Trinchieri, Giorgio, Gajewski, Thomas F, Ascierto, Paolo A, Fox, Bernard A

“…Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation of tissue samples obtained during surgical resection of the…”
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Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative by Butler-Laporte, Guillaume, Povysil, Gundula, Kosmicki, Jack A, Cirulli, Elizabeth T, Drivas, Theodore, Furini, Simone, Saad, Chadi, Schmidt, Axel, Olszewski, Pawel, Korotko, Urszula, Quinodoz, Mathieu, Çelik, Elifnaz, Kundu, Kousik, Walter, Klaudia, Jung, Junghyun, Stockwell, Amy D, Sloofman, Laura G, Jordan, Daniel M, Thompson, Ryan C, Del Valle, Diane, Simons, Nicole, Cheng, Esther, Sebra, Robert, Schadt, Eric E, Kim-Schulze, Seunghee, Gnjatic, Sacha, Merad, Miriam, Buxbaum, Joseph D, Beckmann, Noam D, Charney, Alexander W, Przychodzen, Bartlomiej, Chang, Timothy, Pottinger, Tess D, Shang, Ning, Brand, Fabian, Fava, Francesca, Mari, Francesca, Chwialkowska, Karolina, Niemira, Magdalena, Pula, Szymon, Baillie, J Kenneth, Stuckey, Alex, Salas, Antonio, Bello, Xabier, Pardo-Seco, Jacobo, Gómez-Carballa, Alberto, Rivero-Calle, Irene, Martinón-Torres, Federico, Ganna, Andrea, Karczewski, Konrad J, Veerapen, Kumar, Bourgey, Mathieu, Bourque, Guillaume, Eveleigh, Robert Jm, Forgetta, Vincenzo, Morrison, David, Langlais, David, Lathrop, Mark, Mooser, Vincent, Nakanishi, Tomoko, Frithiof, Robert, Hultström, Michael, Lipcsey, Miklos, Marincevic-Zuniga, Yanara, Nordlund, Jessica, Schiabor Barrett, Kelly M, Lee, William, Bolze, Alexandre, White, Simon, Riffle, Stephen, Tanudjaja, Francisco, Sandoval, Efren, Neveux, Iva, Dabe, Shaun, Casadei, Nicolas, Motameny, Susanne, Alaamery, Manal, Massadeh, Salam, Aljawini, Nora, Almutairi, Mansour S, Arabi, Yaseen M, Alqahtani, Saleh A, Al Harthi, Fawz S, Almutairi, Amal, Alqubaishi, Fatima, Alotaibi, Sarah, Binowayn, Albandari, Alsolm, Ebtehal A, El Bardisy, Hadeel, Fawzy, Mohammad, Cai, Fang, Soranzo, Nicole, Butterworth, Adam, Geschwind, Daniel H, Arteaga, Stephanie, Stephens, Alexis, Butte, Manish J, Boutros, Paul C, Yamaguchi, Takafumi N, Tao, Shu

“…Host genetics is a key determinant of COVID-19 outcomes. Previously, the COVID-19 Host Genetics Initiative genome-wide association study used common variants…”
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Myeloid Cell-associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing by Wang, Li, Sfakianos, John P, Beaumont, Kristin G, Akturk, Guray, Horowitz, Amir, Sebra, Robert P, Farkas, Adam M, Gnjatic, Sacha, Hake, Austin, Izadmehr, Sudeh, Wiklund, Peter, Oh, William K, Szabo, Peter M, Wind-Rotolo, Megan, Unsal-Kacmaz, Keziban, Yao, Xin, Schadt, Eric, Sharma, Padmanee, Bhardwaj, Nina, Zhu, Jun, Galsky, Matthew D

“…To define dominant molecular and cellular features associated with PD-1/PD-L1 blockade resistance in metastatic urothelial cancer. We pursued an unbiased…”
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Anti-Integrin αvβ6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis by Livanos, Alexandra E., Dunn, Alexandra, Fischer, Jeremy, Ungaro, Ryan C., Turpin, Williams, Lee, Sun-Ho, Rui, Shumin, Del Valle, Diane Marie, Jougon, Julia J., Martinez-Delgado, Gustavo, Riddle, Mark S., Murray, Joseph A., Laird, Renee M., Torres, Joana, Agrawal, Manasi, Magee, Jared S., Dervieux, Thierry, Gnjatic, Sacha, Sheppard, Dean, Sands, Bruce E., Porter, Chad K., Croitoru, Kenneth, Petralia, Francesca, Abreu, Maria, Beck, Paul, Bernstein, Charles, Croitoru, Kenneth, Dieleman, Leo, Feagan, Brian, Griffiths, Anne, Guttman, David, Jacobson, Kevan, Kaplan, Gilaad, Krause, Denis O., Madsen, Karen, Marshall, John, Moayyedi, Paul, Ropeleski, Mark, Seidman, Ernest, Silverberg, Mark, Snapper, Scott, Stadnyk, Andy, Steinhart, Hillary, Surette, Michael, Turner, Dan, Walters, Thomas, Vallance, Bruce, Aumais, Guy, Bitton, Alain, Cino, Maria, Critch, Jeff, Denson, Lee, Deslandres, Colette, El-Matary, Wael, Herfarth, Hans, Higgins, Peter, Huynh, Hien, Hyams, Jeff, Mack, David, McGrath, Jerry, Otley, Anthony, Panancionne, Remo, Shapiro, Jason, Shah, Samir, Leleiko, Neal S., Colombel, Jean-Frederic, Mehandru, Saurabh

“…Better biomarkers for prediction of ulcerative colitis (UC) development and prognostication are needed. Anti-integrin αvβ6 (anti-αvβ6) autoantibodies have been…”
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Intraepithelial CD8+ Tumor-Infiltrating Lymphocytes and a High $CD8^+/regulatory$ T Cell Ratio Are Associated with Favorable Prognosis in Ovarian Cancer by Sato, Eiichi, Olson, Sara H., Jiyoung Ahn, Brian Bundy, Nishikawa, Hiroyoshi, Qian, Feng, Jungbluth, Achim A., Denise Frosina, Gnjatic, Sacha, Christine Ambrosone, Kepner, James, Tosin Odunsi, Ritter, Gerd, Shashikant Lele, Chen, Yao-Tseng, Haruo Ohtani, Old, Lloyd J., Odunsi, Kunle

“…In a recent report, [Zhang et al. (2003) N. Engl. J. Med. 348,203-213], the presence of CD3+ tumor-infiltrating lymphocytes (TILs) was found to correlate with…”
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A196 CSF2 AUTOANTIBODIES AS A SEROLOGICAL MARKER FOR CROHN'S DISEASE by Tai, S, Del Valle, D, Urango, R, Croitoru, K, Gnjatic, S, Korzenik, J, Colombel, J, Mortha, A

“…Abstract Background Crohn’s disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract that severely affects quality of life. Despite…”
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Phase I Clinical Trial of Mixed Bacterial Vaccine (Coley's Toxins) in Patients with NY-ESO-1 Expressing Cancers: Immunological Effects and Clinical Activity by KARBACH, Julia, NEUMANN, Antje, RITTER, Gerd, JÄGER, Elke, BRAND, Kathrin, WAHLE, Claudia, SIEGEL, Ekkehard, MAEURER, Markus, RITTER, Erika, TSUJI, Takamasa, GNJATIC, Sacha, OLD, Lloyd J

“…Mixed bacterial vaccine (MBV, Coley's toxins) is a historical, vaguely defined preparation of heat-inactivated Streptococcus pyogenes and Serratia marcescens…”
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Spatial analyses of immune cell infiltration in cancer: current methods and future directions. A report of the International Immuno‐Oncology Biomarker Working Group on Breast Cancer by Broeckx, Glenn, Jahangir, Chowdhury Arif, Verbandt, Sara, Thagaard, Jeppe, Khiroya, Reena, Abduljabbar, Khalid, Acosta Haab, Gabriela, Acs, Balazs, Almeida, Jonas S, Azmoudeh‐Ardalan, Farid, Badve, Sunil, Baharun, Nurkhairul Bariyah, Bheemaraju, Vydehi, Botinelly Mendonça Fujimoto, Luciana, Bouchmaa, Najat, Cheang, Maggie Chon U, Ciompi, Francesco, Cooper, Lee AD, Coosemans, An, Corredor, Germán, Dantas Portela, Flavio Luis, Demaria, Sandra, Dudgeon, Sarah N, Elghazawy, Mahmoud, Ely, Scott, Fernandez‐Martín, Claudio, Fox, Stephen B, Gallagher, William M, Giltnane, Jennifer M, Gonzalez‐Ericsson, Paula I, Grigoriadis, Anita, Halama, Niels, Harbhajanka, Aparna, Hardas, Alexandros, Hewitt, Stephen, Horlings, Hugo M, Hytopoulos, Evangelos, Irshad, Sheeba, Janssen, Emiel AM, Kahila, Mohamed, Kawaguchi, Kosuke, Kharidehal, Durga, Khramtsov, Andrey I, Kiraz, Umay, Kirtani, Pawan, Kodach, Liudmila L, Korski, Konstanty, Kovács, Anikó, Lang‐Schwarz, Corinna, Larsimont, Denis, Lennerz, Jochen K, Lerousseau, Marvin, Ly, Amy, Maley, Sai K, Manur Narasimhamurthy, Vidya, Marks, Douglas K, McDonald, Elizabeth S, Michiels, Stefan, Minhas, Fayyaz ul Amir Afsar, Mittal, Shachi, Mushtaq, Shamim, Nighat, Hussain, Papathomas, Thomas, Pinard, Christopher J, Pinto‐Cardenas, Juan Carlos, Pruneri, Giancarlo, Pusztai, Lajos, Rahman, Arman, Rajpoot, Nasir Mahmood, Rapoport, Bernardo Leon, Rau, Tilman T, Reis‐Filho, Jorge S, Ribeiro, Joana M, Rimm, David, Salto‐Tellez, Manuel, Sayed, Shahin, Siziopikou, Kalliopi P, Stenzinger, Albrecht, Sughayer, Maher A, Sur, Daniel, Symmans, Fraser, Tanaka, Sunao, Taxter, Timothy, Tejpar, Sabine, Teuwen, Jonas, Thompson, E Aubrey, Tramm, Trine, Verghese, Gregory E, Vieth, Michael, Wahab, Noorul, Walter, Thomas, Wen, Hannah Y, Yang, Wentao, Adams, Sylvia, Bartlett, John Mark Seaverns, Loibl, Sibylle, Savas, Peter, Loi, Sherene, Salgado, Roberto, Specht Stovgaard, Elisabeth

“…Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in…”
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Image‐based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno‐oncology Biomarker Working Group on Breast Cancer by Jahangir, Chowdhury Arif, Page, David B, Broeckx, Glenn, Gonzalez, Claudia A, Burke, Caoimbhe, Reis‐Filho, Jorge S, Ly, Amy, Harms, Paul W, Vieth, Michael, Kos, Zuzana, Diest, Paul J, Thagaard, Jeppe, Khiroya, Reena, Acosta Haab, Gabriela, Acs, Balazs, Adams, Sylvia, Almeida, Jonas S, Alvarado‐Cabrero, Isabel, Azmoudeh‐Ardalan, Farid, Badve, Sunil, Baharun, Nurkhairul Bariyah, Bellolio, Enrique R, Blenman, Kim RM, Cheang, Maggie Chon U, Ciompi, Francesco, Cooper, Lee AD, Coosemans, An, Corredor, Germán, Dantas Portela, Flavio Luis, Demaria, Sandra, Dudgeon, Sarah N, Elghazawy, Mahmoud, Fernandez‐Martín, Claudio, Fineberg, Susan, Fox, Stephen B, Giltnane, Jennifer M, Gnjatic, Sacha, Grigoriadis, Anita, Hanna, Matthew G, Harbhajanka, Aparna, Hart, Steven N, Hartman, Johan, Hewitt, Stephen, Irshad, Sheeba, Janssen, Emiel AM, Kataoka, Tatsuki R, Kawaguchi, Kosuke, Khramtsov, Andrey I, Kiraz, Umay, Kirtani, Pawan, Kodach, Liudmila L, Korski, Konstanty, Akturk, Guray, Scott, Ely, Lænkholm, Anne‐Vibeke, Lennerz, Jochen K, Lerousseau, Marvin, Li, Xiaoxian, Maley, Sai K, Manur Narasimhamurthy, Vidya, Marks, Douglas K, Mehrotra, Ravi, Michiels, Stefan, Minhas, Fayyaz ul Amir Afsar, Moore, David A, Mushtaq, Shamim, Nighat, Hussain, Papathomas, Thomas, Penault‐Llorca, Frederique, Pinard, Christopher J, Pinto‐Cardenas, Juan Carlos, Pruneri, Giancarlo, Rau, Tilman T, Rimm, David, Vincent‐Salomon, Anne, Saltz, Joel, Sayed, Shahin, Hytopoulos, Evangelos, Sotiriou, Christos, Sur, Daniel, Tanaka, Sunao, Taxter, Timothy, Tejpar, Sabine, Teuwen, Jonas, Thompson, E Aubrey, Tramm, Trine, Tran, William T, Laak, Jeroen, Verghese, Gregory E, Viale, Giuseppe, Wahab, Noorul, Walter, Thomas, Wen, Hannah Y, Bartlett, John, Loibl, Sibylle, Denkert, Carsten, Savas, Peter, Loi, Sherene, Specht Stovgaard, Elisabeth, Rahman, Arman

“…Recent advances in the field of immuno‐oncology have brought transformative changes in the management of cancer patients. The immune profile of tumours has…”
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Ipilimumab Increases Activated T Cells and Enhances Humoral Immunity in Patients With Advanced Melanoma by WEBER, Jeffrey S, HAMID, Omid, CHASALOW, Scott D, WU, Dianna Y, PARKER, Susan M, GALBRAITH, Susan, GNJATIC, Sacha, BARMAN, David

“…Ipilimumab, a fully human monoclonal antibody, which blocks cytotoxic T-lymphocyte antigen-4, has demonstrated an improvement in overall survival in 2 phase…”
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