Search Results - "Gniffke, Edward P"

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  1. 1

    A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2 by Tsegay, Kaleb B., Adeyemi, Christiana M., Gniffke, Edward P., Sather, D. Noah, Walker, John K., Smith, Stephen E. P.

    Published in Frontiers in pharmacology (14-06-2021)
    “…Repurposed drugs that block the interaction between the SARS-CoV-2 spike protein and its receptor ACE2 could offer a rapid route to novel COVID-19 treatments…”
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    Journal Article
  2. 2

    Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models by Brown, Emily A, Lautz, Jonathan D, Davis, Tessa R, Gniffke, Edward P, VanSchoiack, Alison A W, Neier, Steven C, Tashbook, Noah, Nicolini, Chiara, Fahnestock, Margaret, Schrum, Adam G, Smith, Stephen E P

    Published in Molecular autism (15-09-2018)
    “…Autism spectrum disorders (ASDs) are a heterogeneous group of behaviorally defined disorders and are associated with hundreds of rare genetic mutations and…”
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    Remodeling of the Homer-Shank interactome mediates homeostatic plasticity by Heavner, Whitney E, Lautz, Jonathan D, Speed, Haley E, Gniffke, Edward P, Immendorf, Karen B, Welsh, John P, Baertsch, Nathan A, Smith, Stephen E P

    Published in Science signaling (04-05-2021)
    “…Neurons maintain stable levels of excitability using homeostatic synaptic scaling, which adjusts the strength of a neuron's postsynaptic inputs to compensate…”
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  5. 5

    Synaptic protein interaction networks encode experience by assuming stimulus-specific and brain-region-specific states by Lautz, Jonathan D, Tsegay, Kaleb B, Zhu, Zhiyi, Gniffke, Edward P, Welsh, John P, Smith, Stephen E P

    Published in Cell reports (Cambridge) (30-11-2021)
    “…A core network of widely expressed proteins within the glutamatergic post-synapse mediates activity-dependent synaptic plasticity throughout the brain, but the…”
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  6. 6

    Activity-dependent changes in synaptic protein complex composition are consistent in different detergents despite differential solubility by Lautz, Jonathan D., Gniffke, Edward P., Brown, Emily A., Immendorf, Karen B., Mendel, Ryan D., Smith, Stephen E. P.

    Published in Scientific reports (26-07-2019)
    “…At the post-synaptic density (PSD), large protein complexes dynamically form and dissociate in response to synaptic activity, comprising the biophysical basis…”
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