Search Results - "Glynne, R J"
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1
Design considerations for array CGH to oligonucleotide arrays
Published in Cytometry. Part A (01-10-2005)“…Background Representational oligonucleotide microarray analysis has been developed for detection of single nucleotide polymorphisms and/or for genome copy…”
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Evolutionary Dynamics of Non-coding Sequences Within the Class II Region of the Human MHC
Published in Journal of molecular biology (12-01-1996)“…About 40% (350 kb) of the human MHC class II region has been sequenced and a coordinated effort to sequence the entire MHC is underway. In addition to the…”
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Identifying the MAGUK Protein Carma-1 as a Central Regulator of Humoral Immune Responses and Atopy by Genome-Wide Mouse Mutagenesis
Published in Immunity (Cambridge, Mass.) (01-06-2003)“…In a genome-wide ENU mouse mutagenesis screen a recessive mouse mutation, unmodulated, was isolated with profound defects in humoral immune responses,…”
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Genome-Wide Single-Nucleotide Polymorphism Analysis Defines Haplotype Patterns in Mouse
Published in Proceedings of the National Academy of Sciences - PNAS (18-03-2003)“…The nature and organization of polymorphisms, or differences, between genomes of individuals are of great interest, because these variations can be associated…”
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Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins
Published in Current biology (01-09-1994)“…Intracellular proteins are processed into small peptides that bind HLA class I molecules of the major histocompatibility complex (MHC) in order to be presented…”
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The immune system and gene expression microarrays - new answers to old questions
Published in The Journal of pathology (01-09-2001)“…The recent increase in availability of gene expression technologies has the potential to dramatically expand our understanding of cellular immunology in…”
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Genomic-scale gene expression analysis of lymphocyte growth, tolerance and malignancy
Published in Current Opinion in Immunology (01-04-2000)“…Immunologists are already comfortable with the need for monitoring many different gene products simultaneously. It is a common challenge to remember what…”
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Book Review Journal Article -
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DNA sequencing of the MHC class II region and the chromosome 6 sequencing effort at the Sanger Centre
Published in DNA sequence (1996)“…The human Major Histocompatibility Complex (MHC) is located on the short arm of chromosome 6 (6p21.3) and spans about 4 Mb. According to different gene…”
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Combining mouse congenic strains and microarray gene expression analyses to study a complex trait: the NOD model of type 1 diabetes
Published in Genome research (01-02-2002)“…Combining congenic mapping with microarray expression profiling offers an opportunity to establish functional links between genotype and phenotype for complex…”
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Combining Mouse Congenic Strains and Microarray Gene Expression Analyses to Study a Complex Trait: The NOD Model of Type 1 Diabetes
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