Search Results - "Glynn, Rebecca A."

Prenatal stress and newborn telomere length by Marchetto, Nicole M., MD, Glynn, Rebecca A., BS, Ferry, Mackenzie L., BS, Ostojic, Maja, BS, Wolff, Sandra M., MD, Yao, Ruofan, MD, Haussmann, Mark F., PhD

“…Background The developmental origin of the health and disease hypothesis is based on the premise that many chronic diseases have their roots in fetal…”
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ATM-dependent Phosphorylation of Nemo SQ Motifs Is Dispensable for Nemo-mediated Gene Expression Changes in Response to DNA Double-Strand Breaks by Glynn, Rebecca A, Hayer, Katharina E, Bassing, Craig H

“…In response to DNA double-strand breaks (DSBs), the ATM kinase activates NF-κB factors to stimulate gene expression changes that promote survival and allow…”
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Nemo-Dependent, ATM-Mediated Signals from RAG DNA Breaks at Igk Feedback Inhibit V κ Recombination to Enforce Igκ Allelic Exclusion by Glynn, Rebecca A, Bassing, Craig H

“…Monoallelic AgR gene expression underlies specific adaptive immune responses. AgR allelic exclusion is achieved by sequential initiation of V(D)J recombination…”
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The Cyclin D3 Protein Enforces Monogenic TCRβ Expression by Mediating TCRβ Protein-Signaled Feedback Inhibition of Vβ Recombination by Culberson, Erica J, Shields, Kymberle C, Glynn, Rebecca A, Allyn, Brittney M, Hayer, Katharina E, Bassing, Craig H

“…In jawed vertebrates, adaptive immunity depends on the process of V(D)J recombination creating vast numbers of T and B lymphocytes that each expresses unique…”
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From RAG2 to T Cell Riches and Future Fortunes by Glynn, Rebecca A, Bassing, Craig H

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The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination by Beilinson, Helen A, Glynn, Rebecca A, Yadavalli, Anurupa Devi, Xiao, Jianxiong, Corbett, Elizabeth, Saribasak, Huseyin, Arya, Rahul, Miot, Charline, Bhattacharyya, Anamika, Jones, Jessica M, Pongubala, Jagan M R, Bassing, Craig H, Schatz, David G

“…Immunoglobulin and T cell receptor gene assembly depends on V(D)J recombination initiated by the RAG1-RAG2 recombinase. The RAG1 N-terminal region (NTR; aa…”
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Combined Menin and EGFR Inhibitors Synergize to Suppress Colorectal Cancer via EGFR-Independent and Calcium-Mediated Repression of SKP2 Transcription by Katona, Bryson W, Glynn, Rebecca A, Paulosky, Kayla E, Feng, Zijie, Davis, Caroline I, Ma, Jian, Berry, Corbett T, Szigety, Katherine M, Matkar, Smita, Liu, Yuanyuan, Wang, Haoren, Wu, Yuan, He, Xin, Freedman, Bruce D, Brady, Donita C, Hua, Xianxin

“…Menin is a nuclear epigenetic regulator that can both promote and suppress tumor growth in a highly tissue-specific manner. The role of menin in colorectal…”
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Menin-mediated Repression of Glycolysis in Combination with Autophagy Protects Colon Cancer Against Small-molecule EGFR Inhibitors by Katona, Bryson W, Hojnacki, Taylor, Glynn, Rebecca A, Paulosky, Kayla E, Szigety, Katherine M, Cao, Yan, Zhang, Xuyao, Feng, Zijie, He, Xin, Ma, Jian, Hua, Xianxin

“…Menin serves both tumor suppressor and promoter roles in a highly tumor-specific manner. In colorectal cancer, menin is overexpressed and plays a critical role…”
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Is there a context-dependent advantage of extra-pair mating in Tree Swallows? by Belmaker, Amos, Hallinger, Kelly K, Glynn, Rebecca A, Haussmann, Mark F, Winkler, David W

“…The “good-genes” hypothesis to explain female extra-pair mating states that females benefit from this behavior by acquiring better genes for their offspring…”
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Efficacy of Peptide Receptor Radionuclide Therapy in a United States-Based Cohort of Metastatic Neuroendocrine Tumor Patients: Single-Institution Retrospective Analysis by Katona, Bryson W, Roccaro, Giorgio A, Soulen, Michael C, Yang, Yu-Xiao, Bennett, Bonita J, Riff, Brian P, Glynn, Rebecca A, Wild, Damian, Nicolas, Guillaume P, Pryma, Daniel A, Teitelbaum, Ursina R, Metz, David C

“…The aim of this study was to analyze in a retrospective cohort study the outcomes of a United States-based group of metastatic neuroendocrine tumor (NET)…”
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Menin: Expanding and dichotomous roles in cancer by Katona, Bryson W., Glynn, Rebecca A., Hojnacki, Taylor A., Hua, Xianxin

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Nemo-dependent, ATM-mediated signals from RAG DNA breaks at Igk feedback inhibit Vk recombination to enforce Igκ allelic exclusion by Glynn, Rebecca A., Bassing, Craig H.

“…Mono-allelic antigen receptor (AgR) gene expression underlies specific adaptive immune responses. AgR allelic exclusion is achieved by sequential initiation of…”
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Dna Damage Induced During Antigen Receptor Gene Assembly Signals to Regulate Mechanisms of V(D)J Recombination: Implications for Autoimmunity and Genomic Integrity by Glynn, Rebecca A

“…The adaptive immune system relies on the assembly of unique antigen receptor (AgR) genes through V(D)J recombination during B and T cell development. V(D)J…”
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