Search Results - "Gluch, Angela"

Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis by Grinkevich, Vera V., Nikulenkov, Fedor, Shi, Yao, Enge, Martin, Bao, Wenjie, Maljukova, Alena, Gluch, Angela, Kel, Alexander, Sangfelt, Olle, Selivanova, Galina

“…Targeting “oncogene addiction” is a promising strategy for anticancer therapy. We report a potent inhibition of crucial oncogenes by p53 upon reactivation by…”
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YY1-binding sites provide central switch functions in the PARP-1 gene expression network by Doetsch, Martina, Gluch, Angela, Poznanović, Goran, Bode, Juergen, Vidaković, Melita

“…Evidence is presented for the involvement of the interplay between transcription factor Yin Yang 1 (YY1) and poly(ADP-ribose) polymerase-1 (PARP-1) in the…”
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Inhibition of Glycolytic Enzymes Mediated by Pharmacologically Activated p53 by Zawacka-Pankau, Joanna, Grinkevich, Vera V., Hünten, Sabine, Nikulenkov, Fedor, Gluch, Angela, Li, Hai, Enge, Martin, Kel, Alexander, Selivanova, Galina

“…Unique sensitivity of tumor cells to the inhibition of glycolysis is a good target for anticancer therapy. Here, we demonstrate that the pharmacologically…”
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Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer by Zawacka-Pankau, Joanna, Grinkevich, Vera V, Hünten, Sabine, Nikulenkov, Fedor, Gluch, Angela, Li, Hai, Enge, Martin, Kel, Alexander, Selivanova, Galina

“…Unique sensitivity of tumor cells to the inhibition of glycolysis is a good target for anticancer therapy. Here, we demonstrate that the pharmacologically…”
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Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis by Grinkevich, Vera V., Nikulenkov, Fedor, Shi, Yao, Enge, Martin, Bao, Wenjie, Maljukova, Alena, Gluch, Angela, Kel, Alexander, Sangfelt, Olle, Selivanova, Galina

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PARP-1 Expression in the Mouse is Controlled by an Autoregulatory Loop: PARP-1 Binding to an Upstream S/MAR Element and to a Novel Recognition Motif in its Promoter Suppresses Transcription by Vidaković, Melita, Gluch, Angela, Qiao, Junhua, Oumard, Andrè, Frisch, Matthias, Poznanović, Goran, Bode, Juergen

“…This work identifies central components of a feedback mechanism for the expression of mouse poly(ADP-ribose) polymerase-1 (PARP-1). Using the stress-induced…”
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Dominant genomic structures: Detection and potential signal functions in the interferon-beta domain by Klar, Martin, Stellamanns, Eric, AK, Prashanth, Gluch, Angela, Bode, Juergen

“…Eukaryotic genomes are divided into chromatin domains, which are thought to represent independent regulatory units. Typically, these domains are flanked by…”
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The positive aspects of stress: strain initiates domain decondensation (SIDD) by Winkelmann, Silke, Klar, Martin, Benham, Craig, Prashanth, Ak, Goetze, Sandra, Gluch, Angela, Bode, Juergen

“…The conventional string-based bioinformatic methods of genomic sequence analysis are often insufficient to identify DNA regulatory elements, since many of…”
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