Search Results - "Gloria Brusotti"
-
1
Hovenia dulcis Thumberg: Phytochemistry, Pharmacology, Toxicology and Regulatory Framework for Its Use in the European Union
Published in Molecules (Basel, Switzerland) (09-02-2021)“…Thunberg is an herbal plant, belonging to the Rhamnaceae family, widespread in west Asia, USA, Australia and New Zealand, but still almost unknown in Western…”
Get full text
Journal Article -
2
Nature-derived compounds modulating Wnt/β-catenin pathway: a preventive and therapeutic opportunity in neoplastic diseases
Published in Acta pharmaceutica Sinica. B (01-10-2020)“…The Wnt/β-catenin signaling is a conserved pathway that has a crucial role in embryonic and adult life. Dysregulation of the Wnt/β-catenin pathway has been…”
Get full text
Journal Article -
3
Bio-Guided Fractionation of Stem Bark Extracts from Phyllanthus muellarianus: Identification of Phytocomponents with Anti-Cholinesterase Activity
Published in Molecules (Basel, Switzerland) (20-07-2021)“…A combination of flash chromatography, solid phase extraction, high-performance liquid chromatography, and in vitro bioassays was used to isolate…”
Get full text
Journal Article -
4
Anti-Inflammatory Properties of Bellevalia saviczii Root Extract and Its Isolated Homoisoflavonoid ( Dracol ) Are Mediated by Modification on Calcium Signaling
Published in Molecules (Basel, Switzerland) (17-09-2019)“…is a medicinal plant used as anti-rheumatic and anti-inflammatory herbal remedy in Iraqi-Kurdistan. The aim of this study was to evaluate the anti-inflammatory…”
Get full text
Journal Article -
5
Monolithic Papain-Immobilized Enzyme Reactors for Automated Structural Characterization of Monoclonal Antibodies
Published in Frontiers in molecular biosciences (09-11-2021)“…The characterization of monoclonal antibodies (mAbs) requires laborious and time-consuming sample preparation steps before the liquid chromatography–mass…”
Get full text
Journal Article -
6
Nature-derived compounds modulating Wnt/ -catenin pathway: a preventive and therapeutic opportunity in neoplastic diseases
Published in Acta pharmaceutica Sinica. B (01-10-2020)Get full text
Journal Article -
7
Bioassay-Guided Isolation of Nigracin, Responsible for the Tissue Repair Properties of Drypetes Klainei Stem Bark
Published in Frontiers in pharmacology (23-01-2020)“…Pierre ex Pax is used in Cameroon by Baka people in the wound healing process and for the treatment of burns. In a previous paper we demonstrated the ability…”
Get full text
Journal Article -
8
Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis
Published in Scientific reports (18-07-2017)“…PPAR antagonists are ligands that bind their receptor with high affinity without transactivation activity. Recently, they have been demonstrated to maintain…”
Get full text
Journal Article -
9
Analytical settings for in-flow biocatalytic reaction monitoring
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-10-2021)“…The interest towards in-flow biocatalytic processes using immobilised enzyme reactors (IMERs) has grown significantly over the past ten years. In an IMER, the…”
Get full text
Journal Article -
10
Advances on Size Exclusion Chromatography and Applications on the Analysis of Protein Biopharmaceuticals and Protein Aggregates: A Mini Review
Published in Chromatographia (2018)“…Biopharmaceutical drugs are large, complex protein molecules derived from living cells. The characterization of the protein-based products is a complicated and…”
Get full text
Journal Article -
11
Affinity-based separation methods for the study of biological interactions: The case of peroxisome proliferator-activated receptors in drug discovery
Published in Methods (San Diego, Calif.) (15-08-2018)“…•Affinity chromatographic methods based on immobilized PPARs receptors are described.•Selection of PPARs ligands from natural and synthetic sources is…”
Get full text
Journal Article -
12
Cyclodextrin- and solvent-modified micellar electrokinetic chromatography for the determination of captopril, hydrochlorothiazide and their impurities: A Quality by Design approach
Published in Talanta (Oxford) (01-11-2016)“…A fast and selective capillary electrophoresis method has been developed for the simultaneous determination of the antihypertensive drugs captopril and…”
Get full text
Journal Article -
13
Isolation and characterization of the alkaloid Nitidine responsible for the traditional use of Phyllanthus muellerianus (Kuntze) Excell stem bark against bacterial infections
Published in Journal of pharmaceutical and biomedical analysis (01-02-2015)“…This study reports the validation of Phyllanthus muellerianus stem bark traditional use through the isolation and identification of the bioactive compound, the…”
Get full text
Journal Article -
14
A chemometric assessment and profiling of the essential oils from Hibiscus sabdariffa L. from Kurdistan, Iraq
Published in Natural product research (01-05-2022)“…L. is a tropical plant belonging to the Malvaceae family. In Kurdistan, the Autonomous Region of Iraq, water infusion of calyces is recommended for the…”
Get full text
Journal Article -
15
Antimicrobial and phytochemical properties of stem bark extracts from Piptadeniastrum africanum (Hook f.) Brenan
Published in Industrial crops and products (01-05-2013)“…► Antimicrobial activity of the Piptadeniastrum africanum bark extracts. ► Antifungal activity against Pyricularia grisea found in the saponin mixture. ►…”
Get full text
Journal Article -
16
Extensive phytochemical investigation of the polar constituents of Diospyros bipindensis Gürke traditionally used by Baka pygmies
Published in Phytochemistry (Oxford) (01-12-2013)“…•The extracts of the bark of Diospyros bipindensis were active against Candida albicans.•HPLC profiles of the polar extracts revealed a complex glycoside…”
Get full text
Journal Article -
17
Chemical Composition and Antimicrobial Activity of the Volatile Fractions from Leaves and Flowers of the Wild Iraqi Kurdish Plant Prangos peucedanifolia Fenzl
Published in Chemistry & biodiversity (01-02-2013)“…The volatile fractions isolated from Prangos peucedanifolia Fenzl leaves and flowers were investigated for their phytochemical composition and biological…”
Get full text
Journal Article -
18
Optimum extraction process of polyphenols from Bridelia grandis stem bark using experimental design
Published in Journal of separation science (01-06-2010)“…Euphorbiaceae barks are known to contain an appreciable amount of polyphenolic compounds responsible for several biological activities. Preliminary extraction…”
Get full text
Journal Article -
19
Polyacrylate/polyacrylate-PEG biomaterials obtained by high internal phase emulsions (HIPEs) with tailorable drug release and effective mechanical and biological properties
Published in Materials Science & Engineering C (01-12-2019)“…The paper focuses on the preparation of polyacrylate based biomaterials designed as patches for dermal/transdermal drug delivery using materials obtained by…”
Get full text
Journal Article -
20
Enantiomeric separation of 2-aryloxyalkyl- and 2-arylalkyl-2-aryloxyacetic acids on a Penicillin G Acylase-based chiral stationary phase: Influence of the chemical structure on retention and enantioselectivity
Published in Journal of pharmaceutical and biomedical analysis (18-10-2007)“…The chiral recognition mechanism of Penicillin G Acylase (PGA) was investigated with a set of 18 new chiral acidic compounds. A series of 2-aryloxyalkyl- and…”
Get full text
Journal Article