Search Results - "Glinski, J A"

Synthesis of congeners and prodrugs. 3. Water-soluble prodrugs of taxol with potent antitumor activity by Deutsch, H. M, Glinski, J. A, Hernandez, M, Haugwitz, R. D, Narayanan, V. L, Suffness, M, Zalkow, Leon H

“…Taxol has shown good in vivo antitumor activity in a number of test systems. The formulation of taxol for antitumor testing has been difficult. Esterification…”
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Pyrrolizidine Alkaloids from Cynoglossum creticum. Synthesis of the Pyrrolizidine Alkaloids Echinatine, Rinderine, and Analogues by Asibal, Clarita F, Glinski, Jan A, Gelbaum, Leslie T, Zalkow, Leon H

“…Reinvestigation of Cynoglossum creticum led to the isolation of the previously reported echinatine [1] and heliosupine [2] as well as rinderine [3],…”
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Synthesis of pyrrolizidine alkaloids indicine, intermedine, lycopsamine, and analogs and their N-oxides. Potential antitumor agents by Zalkow, Leon H, Glinski, Jan A, Gelbaum, Leslie T, Fleischmann, Thomas J, McGowan, Laureen S, Gordon, Maureen M

“…(-)- and (+)-trachelanthic and (-)- and (+)-viridifloric acids were synthesized and their isopropylidene derivatives were regiospecifically coupled, at C-9,…”
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Anonamine, C19H27NO7, neosenkirkine, C19H27NO6, and hydroxysenkirkine, C19H27NO7.CH3OH. Macrocyclic secopyrrolizidine alkaloids from Senecio anonymus Wood by Glinski, J A, Asibal, C F, Van Derveer, D, Zalkow, L H

“…lambda(Mo K alpha) = 0.71069 A, T = 298 K. Anonamine (I) (12,21-dihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione): C19H27NO7, Mr = 381.2, monoclinic, C2, a…”
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Semisynthetic pyrrolizidine alkaloid N-oxide antitumor agents. Esters of heliotridine by Zalkow, Leon H, Glinski, Jan A, Gelbaum, Leslie T, Moore, David, Melder, Deborah, Powis, Garth

“…The C-9 and C-7 monoesters and C-7, C-9 diesters of heliotridine with (S)-(+) and (R)-(-)-2-hydroxy-2-phenylbutyric acid were prepared, converted into their…”
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Inactivation of cell surface receptors by pheophorbide a, a green pigment isolated from Psychotria acuminata by Glinski, J A, David, E, Warren, T C, Hansen, G, Leonard, S F, Pitner, P, Pav, S, Arvigo, R, Balick, M J, Panta, E

“…The inhibition of cytokine and monoclonal antibody binding cell surfaces caused by an extract of Psychotria acuminata, a medicinal plant used in the…”
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Macrocyclic Pyrrolizidine Alkaloids from Senecio anonymus. Separation of a Complex Alkaloid Extract Using Droplet Counter-Current Chromatography by Zalkow, Leon H, Asibal, Clarita F, Glinski, Jan A, Bonetti, Sandra J, Gelbaum, Leslie T, VanDerveer, Donald, Powis, Garth

“…Ten 12-membered macrocyclic pyrrolizidine alkaloids, all of them esters of the necines, retronecine or otonecine, have been isolated from Senecio anonymus. The…”
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Alkaloids from Eschscholzia californica and Their Capacity to Inhibit Binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A Receptors in Vitro by Gafner, S, Dietz, B.M, McPhail, K.L, Scott, I.M, Glinski, J.A, Russell, F.E, McCollom, M.M, Budzinski, J.W, Foster, B.C, Bergeron, C

“…A 70% ethanol extract of California poppy (Eschscholzia californica) was able to bind to 5-HT(1A) and 5-HT(7) receptors at 100 mug/mL. The subsequent isolation…”
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Synthesis of congeners and prodrugs. III: Water-soluble prodrugs of taxol with potent antitumor activity by DEUTSCH, H. M, GLINSKI, J. A, HERNANDEZ, M, HAUGWITZ, R. D, NARAYANAN, V. L, SUFFNESS, M, ZALKOW, L. H

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Hetisine derivatives. II: Novel rearrangement of 11-dehydrohetisine and 2,11-didehydrohetisine by JOSHI, B. S, GLINSKI, J. A, VARUGHESE, K. I, PELLETIER, S. W

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Hetisine derivatives. I: Acetylation and oxidation of hetisine by GLINSKI, J. A, JOSHI, B. S, QUING PING JIANG, PELLETIER, S. W

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Hetisine derivatives. III: Rearrangement of 11-acetyl-2,13-didehydrohetisine and 13-dehydro-2,11-diacetylhetisine by QINGPING JIANG, GLINSKI, J. A, JOSHI, B. S, MADDRY, J. A, NEWTON, M. G, PELLETIER, S. W

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The structures of four new C219-diterpenoid alkaloids from Aconitum forrestii Stapf by PELLETIER, S. W, JOSHI, B. S, GLINSKI, J. A, CHOKSHI, H. P, CHEN, S, KRISHNA BHANDARY, KUANTEE GO

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Deltatsine, a new C19-diterpenoid alkaloid from Delphinium tatsienense franch by JOSHI, B. S, GLINSKI, J. A, CHOKSHI, H. P, SZU-YING CHEN, SRIVASTAVA, S. K, PELLETIER, S. W

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Tatsirine, a diterpenoid alkaloid from Delphinium tatsienense franch by XIAOLIN ZHANG, SNYDER, J. K

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The Diterpenoid Alkaloids of Delphinium tatsienense Franch by William Pelletier, S., A. Glinski, Jan, S. Joshi, B., Chen, Szu-ying

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Comparative purification of recombinant HIV-1 and HIV-2 reverse transcriptase: preparation of heterodimeric enzyme devoid of unprocessed gene product by Warren, T C, Miglietta, J J, Shrutkowski, A, Rose, J M, Rogers, S L, Lubbe, K, Shih, C K, Caviness, G O, Ingraham, R, Palladino, D E

“…A procedure for producing and purifying recombinant HIV-1 and HIV-2 reverse transcriptase (RT) is described. These enzymes are produced by Escherichia…”
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The origin of oxonitine: a potassium permanganate oxidation product of aconitine by Pelletier, S. William, Glinski, Jan A, Mody, Naresh V

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Unusual Hetisine Rearrangement Products by William Pelletier, S., A. Glinski, Jan, I. Varughese, Kottayil, Maddry, Joseph, V. Mody, Naresh

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