Search Results - "Glickman, Randolph D."

Characterization of Pressure Transients Generated by Nanosecond Electrical Pulse (nsEP) Exposure by Roth, Caleb C., Barnes Jr, Ronald A., Ibey, Bennett L., Beier, Hope T., Christopher Mimun, L., Maswadi, Saher M., Shadaram, Mehdi, Glickman, Randolph D.

“…The mechanism(s) responsible for the breakdown (nanoporation) of cell plasma membranes after nanosecond pulse (nsEP) exposure remains poorly understood…”
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Evaluation of the Genetic Response of U937 and Jurkat Cells to 10-Nanosecond Electrical Pulses (nsEP) by Roth, Caleb C, Glickman, Randolph D, Tolstykh, Gleb P, Estlack, Larry E, Moen, Erick K, Echchgadda, Ibtissam, Beier, Hope T, Barnes, Jr, Ronald A, Ibey, Bennett L

“…Nanosecond electrical pulse (nsEP) exposure activates signaling pathways, produces oxidative stress, stimulates hormone secretion, causes cell swelling and…”
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Intraocular Injection of HyStem Hydrogel Is Tolerated Well in the Rabbit Eye by Glickman, Randolph D, Onorato, Michael, Campos, Maria M, O'Boyle, Michael P, Singh, Ratnesh K, Zarembinski, Thomas I, Binette, Francois, Nasonkin, Igor O

“…To determine the long-term biocompatibility of HyStem hydrogel in the rabbit eye for use as a carrier for cell or drug delivery into the ocular space. HyStem…”
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All-optical optoacoustic microscopy based on probe beam deflection technique by Maswadi, Saher M., Ibey, Bennett L., Roth, Caleb C., Tsyboulski, Dmitri A., Beier, Hope T., Glickman, Randolph D., Oraevsky, Alexander A.

“…Optoacoustic (OA) microscopy using an all-optical system based on the probe beam deflection technique (PBDT) for detection of laser-induced acoustic signals…”
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Phototoxicity to the Retina: Mechanisms of Damage by Glickman, Randolph D.

“…Light damage to the retina occurs through three general mechanisms involving thermal, mechanical, or photochemical effects. The particular mechanism activated…”
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Ultraviolet Phototoxicity to the Retina by Glickman, Randolph D

“…OBJECTIVE:This overview of ultraviolet (UV) phototoxicity considers the interaction of UVA and short-wavelength VIS light with the retina and retinal pigment…”
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An adaptable HPLC method for the analysis of frequently used antibiotics in ocular samples by Davis, Lindsay T., Kumar, Neeru, Nijm, Lisa M., Ulanski, Lawrence J., Tu, Elmer Y., Fiscella, Richard G., Peterson, Randal J., Glickman, Randolph D.

“…Four different antibiotics, delivered individually to rabbit eyes via hydrophilic intraocular lenses soaked in the drug solution prior to implantation, were…”
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Adult human dermal fibroblasts exposed to nanosecond electrical pulses exhibit genetic biomarkers of mechanical stress by Roth, Caleb C, Glickman, Randolph D, Martens, Stacey L, Echchgadda, Ibtissam, Beier, Hope T, Barnes, Jr, Ronald A, Ibey, Bennett L

“…Exposure of cells to very short (<1 µs) electric pulses in the megavolt/meter range have been shown to cause a multitude of effects, both physical and…”
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Regulation of DNA Damage Response by Estrogen Receptor β-Mediated Inhibition of Breast Cancer Associated Gene 2 by Lee, Yuan-Hao, Sun, Youping, Gerweck, Leo E, Glickman, Randolph D

“…Accumulating evidence suggests that ubiquitin E3 ligases are involved in cancer development as their mutations correlate with genomic instability and genetic…”
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Ursolic Acid-Regulated Energy Metabolism-Reliever or Propeller of Ultraviolet-Induced Oxidative Stress and DNA Damage? by Lee, Yuan-Hao, Sun, Youping, Glickman, Randolph D

“…Ultraviolet (UV) light is a leading cause of diseases, such as skin cancers and cataracts. A main process mediating UV-induced pathogenesis is the production…”
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Ursolic acid differentially modulates apoptosis in skin melanoma and retinal pigment epithelial cells exposed to UV–VIS broadband radiation by Lee, Yuan-Hao, Wang, Exing, Kumar, Neeru, Glickman, Randolph D.

“…The signaling pathways via mTOR (mammalian target of rapamycin) and AMPK (AMP-activated protein kinase) play key roles in transcription, translation and…”
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Up-regulation of Adiponectin by Resveratrol: THE ESSENTIAL ROLES OF THE Akt/FOXO1 AND AMP-ACTIVATED PROTEIN KINASE SIGNALING PATHWAYS AND DsbA-L by Wang, Anping, Liu, Meilian, Liu, Xianling, Dong, Lily Q, Glickman, Randolph D, Slaga, Thomas J, Zhou, Zhiguang, Liu, Feng

“…The natural polyphenol resveratrol (RSV) displays a wide spectrum of health beneficial activities, yet the precise mechanisms remain to be fully elucidated…”
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Photothermal killing of Staphylococcus aureus using antibody-targeted gold nanoparticles by Millenbaugh, Nancy J, Baskin, Jonathan B, DeSilva, Mauris N, Elliott, W Rowe, Glickman, Randolph D

“…The continued emergence of multidrug resistant bacterial infections and the decline in discovery of new antibiotics are major challenges for health care…”
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Eye Shielding During Head CT Scans: Dose Reduction and Image Quality Evaluation by Lee, Yuan-Hao, Yang, Shih-Hung, Lin, Yen-Kuang, Glickman, Randolph D., Chen, Chia-Yuen, Chan, Wing P.

“…In this study, we assessed the radiation dose to the lens and the impacts of various eye shields using either a fixed or modulated tube current. Patients…”
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Resveratrol inhibits obesity‐associated adipose tissue dysfunction and tumor growth in a mouse model of postmenopausal claudin‐low breast cancer by Rossi, Emily L., Khatib, Subreen A., Doerstling, Steven S., Bowers, Laura W., Pruski, Melissa, Ford, Nikki A., Glickman, Randolph D., Niu, Mengmeng, Yang, Peiying, Cui, Zhengrong, DiGiovanni, John, Hursting, Stephen D.

“…Adipose tissue dysregulation, a hallmark of obesity, contributes to a chronic state of low‐grade inflammation and is associated with increased risk and…”
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Optoacoustic Multispectral Imaging of Radiolucent Foreign Bodies in Tissue by Page, Leland, Maswadi, Saher, Glickman, Randolph D.

“…Optoacoustic imaging is an emerging medical technology that uniquely combines the absorption contrast of optical imaging and the penetration depth of…”
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Development of a protocol for maintaining viability while shipping organoid‐derived retinal tissue by Singh, Ratnesh K., Winkler, Paige, Binette, Francois, Glickman, Randolph D., Seiler, Magdalene, Petersen‐Jones, Simon M., Nasonkin, Igor O.

“…Retinal organoid technology enables generation of an inexhaustible supply of three‐dimensional retinal tissue from human pluripotent stem cells (hPSCs) for…”
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Antitumor Effects of Ursolic Acid in a Mouse Model of Postmenopausal Breast Cancer by De Angel, Rebecca E, Smith, Sarah M, Glickman, Randolph D, Perkins, Susan N, Hursting, Stephen D

“…Over the past two decades, bioactive natural compounds have been shown to be a plausible adjunct to the treatment of breast cancer, the second leading cause of…”
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Low-Level Primary Blast Causes Acute Ocular Trauma in Rabbits by Jones, Kirstin, Choi, Jae-Hyek, Sponsel, William E, Gray, Walt, Groth, Sylvia L, Glickman, Randolph D, Lund, Brian J, Reilly, Matthew A

“…The objective of this study was to determine whether clinically significant ocular trauma can be induced by a survivable isolated primary blast using a live…”
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Anatomical manifestations of primary blast ocular trauma observed in a postmortem porcine model by Sherwood, Daniel, Sponsel, William E, Lund, Brian J, Gray, Walt, Watson, Richard, Groth, Sylvia L, Thoe, Kimberly, Glickman, Randolph D, Reilly, Matthew A

“…We qualitatively describe the anatomic features of primary blast ocular injury observed using a postmortem porcine eye model. Porcine eyes were exposed to…”
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