Search Results - "Glenn McEnroe"
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Physiological Role of Silent Receptors of Atrial Natriuretic Factor
Published in Science (American Association for the Advancement of Science) (30-10-1987)“…A ring-deleted analog of atrial natriuretic factor--des[Gln$^{18}$, Ser$^{19}$, Gly$^{20}$, Leu$^{21}$, Gly$^{22}$] ANF$_{4-23}$-NH$_{2}$…”
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Peptides Derived from the Complementarity-determining Regions of Anti-Mac-1 Antibodies Block Intercellular Adhesion Molecule-1 Interaction with Mac-1
Published in The Journal of biological chemistry (06-03-1998)“…Peptides or small molecules that can block the interaction of the integrin Mac-1 with its receptor, intercellular adhesion molecule-1 (ICAM-1), have not…”
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Synthesis and Microbiological Evaluation of Novel Tetracyclic Fluoroquinolones
Published in ChemMedChem (20-10-2017)“…Conformationally constrained tetracyclic fluoroquinolones (FQs) were synthesized and profiled for their microbiological spectrum. The installation of a…”
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Identification of Mutations in the italic toggle="yes">mrdA /italic> Gene Encoding PBP2 That Reduce Carbapenem and Diazabicyclooctane Susceptibility of Escherichia coli Clinical Isolates with Mutations in italic toggle="yes">ftsI /italic> (PBP3) and Which Carry italic toggle="yes">bla /italic>NDM-1
Published in mSphere (01-08-2019)“…ABSTRACT Penicillin-binding proteins (PBPs) are essential for bacterial cell wall biosynthesis, and several are clinically validated antibacterial targets of…”
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Targeting endogenous transforming growth factor β receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype
Published in Cancer research (Chicago, Ill.) (01-08-2004)“…Abstract Transforming growth factor-β (TGF-β) suppresses tumor formation by blocking cell cycle progression and maintaining tissue homeostasis. In pancreatic…”
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Identification of Mutations in the mrdA Gene Encoding PBP2 That Reduce Carbapenem and Diazabicyclooctane Susceptibility of Escherichia coli Clinical Isolates with Mutations in ftsI (PBP3) and Which Carry blaNDM-1
Published in mSphere (2019)“…ABSTRACTPenicillin-binding proteins (PBPs) are essential for bacterial cell wall biosynthesis, and several are clinically validated antibacterial targets of…”
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Identification of Mutations in the mrdA Gene Encoding PBP2 That Reduce Carbapenem and Diazabicyclooctane Susceptibility of Escherichia coli Clinical Isolates with Mutations in ftsI (PBP3) and Which Carry bla NDM-1
Published in mSphere (03-07-2019)“…Penicillin-binding proteins (PBPs) are essential for bacterial cell wall biosynthesis, and several are clinically validated antibacterial targets of β-lactam…”
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8
Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model
Published in Neuro-oncology (Charlottesville, Va.) (01-07-2007)“…Transforming growth factor-beta (TGF-beta) is a proinvasive and immunosuppressive cytokine that plays a major role in the malignant phenotype of gliomas. One…”
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Cover Feature: Synthesis and Microbiological Evaluation of Novel Tetracyclic Fluoroquinolones (ChemMedChem 20/2017)
Published in ChemMedChem (20-10-2017)“…The Cover Feature shows the conceptual conversion of clinafloxacin to its tetracyclic analog by addition of a 7‐membered ring, thereby conformationally fixing…”
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Solid phase synthesis of combinatorial libraries using anhydrides as templates
Published in Molecular diversity (1997)“…A simple and general approach to the synthesis of chemical libraries based on a universal anhydride template allows the preparation of large number of…”
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Effects of small C-ANF receptor ligands on plasma levels of atrial natriuretic factor, blood pressure, and renal function in the rat
Published in Canadian journal of physiology and pharmacology (01-10-1991)“…In this article, after a very brief review on ANF receptors, we report our study on the effects of small C-ANF receptor ligands in the rat. Two small ligands…”
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Selective inhibitors of type I receptor kinase block cellular transforming growth factor-β signaling
Published in Biochemical pharmacology (01-07-2004)“…Transforming growth factor (TGFβ) is a 25-kDa dimeric polypeptide that plays a key role in a variety of physiological processes and disease states. Blocking…”
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13
Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1
Published in Cancer research (Chicago, Ill.) (01-08-2004)“…Transforming growth factor-beta (TGF-beta) suppresses tumor formation by blocking cell cycle progression and maintaining tissue homeostasis. In pancreatic…”
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14
Characterization of sequences within heparin-binding EGF-like growth factor that mediate interaction with heparin
Published in The Journal of biological chemistry (28-01-1994)“…Heparin-binding (HB) epidermal growth factor (EGF)-like growth factor (HB-EGF), a member of the EGF protein family, is a potent mitogen for fibroblasts, smooth…”
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TGF-β Receptor I Kinase Inhibitor Downregulates Cytokine Secretion and Multiple Myeloma Cell Growth in the Bone Marrow Microenvironment
Published in Blood (16-11-2004)“…Transforming growth factors (TGFs) have pleiotropic biologic effects on tumor cells and their environment. In multiple myeloma (MM), we have reported that bone…”
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Isolation and primary structure of two peptides with cardioacceleratory and hyperglycemic activity from the corpora cardiaca of Periplaneta americana
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1984)“…Two cardioacceleratory peptides from the corpora cardiaca of Periplaneta americana have been purified by gel filtration and reversed-phase liquid…”
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Clearance receptor and neutral endopeptidase-mediated metabolism of atrial natriuretic factor
Published in The American journal of physiology (01-09-1992)“…A novel small linear C-atrial natriuretic factor receptor ligand [C-ANF-(11-15)] and phosphoramidon (PHO) were used to determine the effects of C-ANF receptor…”
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Isolation of a cDNA Clone Encoding the Amino-Terminal Region of Human Apolipoprotein B
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1986)“…A partial cDNA clone for the B-26 region of apolipoprotein B was isolated from an adult human liver DNA library by screening with an oligonucleotide probe…”
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Structural comparison of human apolipoproteins B-48 and B-100
Published in Biochemistry (Easton) (25-08-1987)“…In this study we have investigated the structural relationship between human apolipoproteins B-48 and B-100 by comparing protein structure and by comparing…”
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