Search Results - "Glen, J. B."

Evaluation of the predictive performance of four pharmacokinetic models for propofol by Glen, J.B., Servin, F.

“…This study has compared the predictive performance of four pharmacokinetic models, two of which are currently incorporated in commercial target-controlled…”
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The development of ‘Diprifusor’: a TCI system for propofol by Glen, J. B.

“…The ‘Diprifusor’ target controlled infusion system has been developed as a standardised infusion system for the administration of propofol by target controlled…”
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Balancing Tricks and Mini-pigs: Steps along the Road to Propofol by Glen, J.B.

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A comparison of the predictive performance of three pharmacokinetic models for propofol using measured values obtained during target‐controlled infusion by Glen, J. B., White, M.

“…Summary We compared the predictive performance of the existing Diprifusor and Schnider models, used for target‐controlled infusion of propofol, with a new…”
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Evaluation of a new method of assessing depth of sedation using two‐choice visual reaction time testing on a mobile phone by Thomson, A. J., Nimmo, A. F., Tiplady, B., Glen, J. B.

“…Summary The utility of two‐choice visual reaction time testing using a specially programmed mobile telephone as a measure of sedation level was investigated in…”
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Pharmacokinetic model selection for target controlled infusions of propofol : assessment of three parameter sets by COETZEE, J. F, GLEN, J. B, WIUM, C. A, BOSHOFF, L

“…Computer-assisted target controlled infusions (TCI) result in prediction errors that are influenced by pharmacokinetic variability among and within patients…”
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Evaluation of the predictive performance of a ‘Diprifusor’ TCI system by Swinhoe, C. F., Peacock, J. E., Glen, J. B., Reilly, C. S.

“…The predictive performance of a ‘Diprifusor’ target controlled infusion system for propofol was examined in 46 patients undergoing major surgery, divided into…”
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Propofol sedation using Diprifusor target-controlled infusion in adult intensive care unit patients by MCMURRAY, T. J, JOHNSTON, J. R, MILLIGAN, K. R, GRANT, I. S, MACKENZIE, S. J, SERVIN, F, JANVIER, G, GLEN, J. B

“…This multicentre, non-comparative study investigated the range of target blood propofol concentrations required to sedate 122 adult intensive care patients…”
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The influence of target concentration, equilibration rate constant (ke0) and pharmacokinetic model on the initial propofol dose delivered in effect‐site target‐controlled infusion by Glen, J. B., Engbers, F. H. M.

“…Summary One advantage of effect‐site target‐controlled infusion is the administration of a larger initial dose of propofol to speed up the induction of…”
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Manual compared with target-controlled infusion of propofol by Russell, D, Wilkes, M P, Hunter, S C, Glen, J B, Hutton, P, Kenny, G N

“…We studied 160 ASA I-II patients, anaesthetized with propofol by infusion, using either a manually controlled or target-controlled infusion system. Patients…”
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Evaluation and optimisation of a target-controlled infusion system for administering propofol to dogs as part of a total intravenous anaesthetic technique during dental surgery by Beths, T, Glen, J B, Reid, J, Monteiro, A M, Nolan, A M

“…The performance of a modified target-controlled infusion system was investigated in 16 dogs undergoing routine dental work, by comparing the predicted…”
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Induction of general anaesthesia by effect‐site target‐controlled infusion of propofol: influence of pharmacokinetic model and ke0 value by Thomson, A. J., Morrison, G., Thomson, E., Beattie, C., Nimmo, A. F., Glen, J. B.

“…Summary We studied the use of a new ke0 value (0.6 min−1) for the Marsh pharmacokinetic model for propofol. Speed of induction and side‐effects produced were…”
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A novel technique to determine an ‘apparent ke0’ value for use with the Marsh pharmacokinetic model for propofol by Thomson, A. J., Nimmo, A. F., Engbers, F. H. M., Glen, J. B.

“…Summary Debate continues over the most appropriate blood–brain equilibration rate constant (ke0) for use with the Marsh pharmacokinetic model for propofol. We…”
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Nomenclature for computer-assisted infusion devices by Glass, P S, Glen, J B, Kenny, G N, Schüttler, J, Shafer, S L

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Administration of propofol by target-controlled infusion in patients undergoing coronary artery surgery by Barvais, L., Rausin, I., Glen, J.B., Hunter, S.C., D'Hulster, D., Cantraine, F., d'Hollander, A.

“…To study the predictive performance of a target-controlled infusion (TCI) system of propofol in patients undergoing coronary artery bypass graft (CABG)…”
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Effect of graded infusion rates of propofol on regional and global left ventricular function in the dog by Puttick, R M, Diedericks, J, Sear, J W, Glen, J B, Foëx, P, Ryder, W A

“…We have studied the effects of graded infusion rates of propofol (0.2-0.5 mg kg-1 min-1) on left ventricular global and regional function, in eight acutely…”
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Propofol administered by a manual infusion regimen by Sear, J W, Glen, J B

“…We have evaluated the clinical utility and blood propofol concentrations produced with two different infusion regimens for propofol, given to supplement 67%…”
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Pharmacodynamic stability of a mixture of propofol and alfentanil by Taylor, I N, Kenny, G N, Glen, J B

“…We studied 40 patients undergoing body surface surgery in a double-blind manner to compare the pharmacodynamic stability of either mixed or separate infusions…”
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Animal studies of the anaesthetic activity of ICI 35 868 by Glen, J B

“…The activity of a new i.v. anesthetic agent ICI 35 868, a compound unrelated to currently used barbiturate, eugenol or steroid agents, has been examined in a…”
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Determination of the optimum ke0 value for use with the Marsh PK model for propofol: 9AP5-7 by Thomson, A J, Nimmo, A F, Glen, J B

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