Search Results - "Glazer, Nicole L"

Sustained and Shorter Bouts of Physical Activity Are Related to Cardiovascular Health by GLAZER, Nicole L, LYASS, Asya, ESLIGER, Dale W, BLEASE, Susan J, FREEDSON, Patty S, MASSARO, Joseph M, MURABITO, Joanne M, VASAN, Ramachandran S

“…Whereas greater physical activity (PA) is known to prevent cardiovascular disease (CVD), the relative importance of performing PA in sustained bouts of…”
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Genetic predictors of medically refractory ulcerative colitis by Haritunians, Talin, Taylor, Kent D., Targan, Stephan R., Dubinsky, Marla, Ippoliti, Andrew, Kwon, Soonil, Guo, Xiuqing, Melmed, Gil Y., Berel, Dror, Mengesha, Emebet, Psaty, Bruce M., Glazer, Nicole L., Vasiliauskas, Eric A., Rotter, Jerome I., Fleshner, Phillip R., McGovern, Dermot P.B.

“…Background: Acute severe ulcerative colitis (UC) remains a significant clinical challenge and the ability to predict, at an early stage, those individuals at…”
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Circulating fibrosis biomarkers and risk of atrial fibrillation: The Cardiovascular Health Study (CHS) by Rosenberg, Michael A., MD, Maziarz, Marlena, MSc, Tan, Alex Y., MD, Glazer, Nicole L., PhD, Zieman, Susan J., MD, PhD, Kizer, Jorge R., MD, MSc, Ix, Joachim H., MD, MAS, Djousse, Luc, MD, ScD, Siscovick, David S., MD, MPH, Heckbert, Susan R., MD, PhD, Mukamal, Kenneth J., MD, MPH

“…Background Cardiac fibrosis is thought to play a central role in the pathogenesis of atrial fibrillation (AF). Retrospective studies have suggested that…”
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A Pilot Study Identifying Statin Nonadherence With Visit-to-Visit Variability of Low-Density Lipoprotein Cholesterol by Mann, Devin M., MD, Glazer, Nicole L., PhD, Winter, Michael, MS, Paasche-Orlow, Michael K., MD, Muntner, Paul, PhD, Shimbo, Daichi, MD, Adams, William G., MD, Kressin, Nancy R., PhD, Zhang, Yuqing, PhD, Choi, Hyon, MD, Cabral, Howard, PhD

“…Nonadherence to cardiovascular medications such as statins is a common, important problem. Clinicians currently rely on intuition to identify medication…”
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Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project by Musunuru, Kiran, Romaine, Simon P R, Lettre, Guillaume, Wilson, James G, Volcik, Kelly A, Tsai, Michael Y, Taylor, Jr, Herman A, Schreiner, Pamela J, Rotter, Jerome I, Rich, Stephen S, Redline, Susan, Psaty, Bruce M, Papanicolaou, George J, Ordovas, Jose M, Liu, Kiang, Krauss, Ronald M, Glazer, Nicole L, Gabriel, Stacey B, Fornage, Myriam, Cupples, L Adrienne, Buxbaum, Sarah G, Boerwinkle, Eric, Ballantyne, Christie M, Kathiresan, Sekar, Rader, Daniel J

“…Whereas it is well established that plasma lipid levels have substantial heritability within populations, it remains unclear how many of the genetic…”
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Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI by Peters, Bas J.M, Pett, Helmi, Klungel, Olaf H, Stricker, Bruno H. Ch, Psaty, Bruce M, Glazer, Nicole L, Wiggins, Kerri L, Bis, Josh C, de Boer, Anthonius, Maitland-van der Zee, Anke-Hilse

“…Highlights ► We study the influence of 27 candidate genes on statin effectiveness. ► We use myocardial infarction as the primary treatment outcome. ► The…”
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Cerivastatin, genetic variants, and the risk of rhabdomyolysis by MARCIANTE, Kristin D, DURDA, Jon P, KASPERA, Rudiger, BIS, Joshua C, GLAZER, Nicole L, GUO LI, AUSTIN, Thomas R, TAYLOR, Kent D, ROTTER, Jerome I, JAQUISH, Cashell E, KWOK, Pui-Yan, TRACY, Russell P, HECKBERT, Susan R, PSATY, Bruce M, LUMLEY, Thomas, RICE, Ken, MCKNIGHT, Barbara, TOTAH, Rheem A, TAMRAZ, Bani, KROETZ, Deanna L, FUKUSHIMA, Hisayo

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Diabetes Mellitus, Glycemic Control, and Risk of Atrial Fibrillation by Dublin, Sascha, Glazer, Nicole L., Smith, Nicholas L., Psaty, Bruce M., Lumley, Thomas, Wiggins, Kerri L., Page, Richard L., Heckbert, Susan R.

“…BACKGROUND Diabetes may be an independent risk factor for atrial fibrillation. However, results from prior studies are in conflict, and no study has examined…”
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Multiple loci associated with indices of renal function and chronic kidney disease by Smith, Albert V, Boerwinkle, Eric, Dehghan, Abbas, Ida Chen, Yii-Der, Levy, Daniel, Chasman, Daniel I, Sarnak, Mark, Ehret, Georg B, Harris, Tamara B, Scharpf, Robert B, Ruczinski, Ingo, Glazer, Nicole L, Haritunians, Talin, Köttgen, Anna, Hwang, Shih-Jen, Arking, Dan E, Kao, W H Linda, Gudnason, Vilmundur, de Boer, Ian H, Li, Man, Coresh, Josef, Astor, Brad C, van Duijn, Cornelia M, Paré, Guillaume, Launer, Lenore J, Rivadeneira, Fernando, Ridker, Paul M, Lumley, Thomas, Hofman, Albert, Shlipak, Michael G, Benjamin, Emelia J, Uitterlinden, André G, Katz, Ronit, Witteman, Jacqueline C, Siscovick, David, Upadhyay, Ashish, Fox, Caroline S, Aulchenko, Yurii S, Yang, Qiong

“…Chronic kidney disease (CKD) has a heritable component and is an important global public health problem because of its high prevalence and morbidity. We…”
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Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis by Ozawa, Clare R, Banfi, Andrea, Glazer, Nicole L, Thurston, Gavin, Springer, Matthew L, Kraft, Peggy E, McDonald, Donald M, Blau, Helen M

“…Use of long-term constitutive expression of VEGF for therapeutic angiogenesis may be limited by the growth of abnormal blood vessels and hemangiomas. We…”
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A Bivariate Genome-Wide Approach to Metabolic Syndrome: STAMPEED Consortium by KRAJA, Aldi T, VAIDYA, Dhananjay, ABSHER, Devin, GUO LI, QUNYUAN ZHANG, FEITOSA, Mary F, GLAZIER, Nicole L, HARITUNIANS, Talin, HARTIKAINEN, Anna-Liisa, KNOWLES, Joshua W, NORTH, Kari E, IRIBARREN, Carlos, PANKOW, James S, KRAL, Brian, YANEK, Lisa, O'REILLY, Paul F, MCCARTHY, Mark I, JAQUISH, Cashell, COUPER, David J, CHAKRAVARTI, Aravinda, PSATY, Bruce M, BECKER, Lewis C, PROVINCE, Michael A, GOODARZI, Mark O, BOERWINKLE, Eric, QUERTERMOUS, Thomas, PALOTIE, Leena, JARVELIN, Marjo-Riitta, BECKER, Diane M, KARDIA, Sharon L. R, ROTTER, Jerome I, CHEN, Yii-Der Ida, BORECKI, Ingrid B, ASSIMES, Themistocles L, KULLO, Iftikhar J, SOVIO, Ulla, MATHIAS, Rasika A, SUN, Yan V, FRANCESCHINI, Nora

“…OBJECTIVE The metabolic syndrome (MetS) is defined as concomitant disorders of lipid and glucose metabolism, central obesity, and high blood pressure, with an…”
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Reference intervals for plasma L-arginine and the L-arginine:asymmetric dimethylarginine ratio in the Framingham Offspring Cohort by Lüneburg, Nicole, Xanthakis, Vanessa, Schwedhelm, Edzard, Sullivan, Lisa M, Maas, Renke, Anderssohn, Maike, Riederer, Ulrich, Glazer, Nicole L, Vasan, Ramachandran S, Böger, Rainer H

“…L-arginine, as a precursor of NO synthesis, has attracted much scientific attention in recent years. Experimental mouse models suggest that L-arginine…”
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Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology by Levy, Daniel, Neuhausen, Susan L, Hunt, Steven C, Kimura, Masayuki, Hwang, Shih-Jen, Chen, Wei, Bis, Joshua C, Fitzpatrick, Annette L, Smith, Erin, Johnson, Andrew D, Gardner, Jeffrey P, Srinivasan, Sathanur R, Schork, Nicholas, Rotter, Jerome I, Herbig, Utz, Psaty, Bruce M, Sastrasinh, Malinee, Murray, Sarah S, Vasan, Ramachandran S, Province, Michael A, Glazer, Nicole L, Lu, Xiaobin, Cao, Xiaojian, Kronmal, Richard, Mangino, Massimo, Soranzo, Nicole, Spector, Tim D, Berenson, Gerald S, Aviv, Abraham

“…Telomeres are engaged in a host of cellular functions, and their length is regulated by multiple genes. Telomere shortening, in the course of somatic cell…”
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Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels by Barbalic, Maja, Dupuis, Josée, Dehghan, Abbas, Bis, Joshua C., Hoogeveen, Ron C., Schnabel, Renate B., Nambi, Vijay, Bretler, Monique, Smith, Nicholas L., Peters, Annette, Lu, Chen, Tracy, Russell P., Aleksic, Nena, Heeriga, Jan, Keaney, John F., Rice, Kenneth, Lip, Gregory Y.H., Vasan, Ramachandran S., Glazer, Nicole L., Larson, Martin G., Uitterlinden, Andre G., Yamamoto, Jennifer, Durda, Peter, Haritunians, Talin, Psaty, Bruce M., Boerwinkle, Eric, Hofman, Albert, Koenig, Wolfgang, Jenny, Nancy S., Witteman, Jacqueline C., Ballantyne, Christie, Benjamin, Emelia J.

“…P-selectin and intercellular adhesion molecule-1 (ICAM-1) participate in inflammatory processes by promoting adhesion of leukocytes to vascular wall…”
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Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD by KÖTTGEN, Anna, HWANG, Shih-Jen, GUDNASON, Vilmundur, SHLIPAK, Michael G, QIONG YANG, CORESH, Josef, LEVY, Daniel, FOX, Caroline S, LARSON, Martin G, VAN EYK, Jennifer E, QIN FU, BENJAMIN, Emelia J, DEHGHAN, Abbas, GLAZER, Nicole L, LINDA KAO, W. H, HARRIS, Tamara B

“…Common variants in the region of the UMOD gene, which encodes uromodulin (Tamm-Horsfall protein), associate with chronic kidney disease (CKD) and estimated GFR…”
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Cardiometabolic Correlates and Heritability of Fetuin-A, Retinol-Binding Protein 4, and Fatty-Acid Binding Protein 4 in the Framingham Heart Study by Kaess, Bernhard M, Enserro, Danielle M, McManus, David D, Xanthakis, Vanessa, Chen, Ming-Huei, Sullivan, Lisa M, Ingram, Cheryl, O'Donnell, Christoper J, Keaney, John F, Vasan, Ramachandran S, Glazer, Nicole L

“…Context: Fetuin-A, retinol-binding protein 4 (RBP4), and fatty-acid binding protein 4 (FABP4) are novel biomarkers that may link adiposity to insulin…”
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Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk Factors by Yang, Qiong, Köttgen, Anna, Dehghan, Abbas, Smith, Albert V, Glazer, Nicole L, Chen, Ming-Huei, Chasman, Daniel I, Aspelund, Thor, Eiriksdottir, Gudny, Harris, Tamara B, Launer, Lenore, Nalls, Michael, Hernandez, Dena, Arking, Dan E, Boerwinkle, Eric, Grove, Megan L, Li, Man, Linda Kao, W.H, Chonchol, Michel, Haritunians, Talin, Li, Guo, Lumley, Thomas, Psaty, Bruce M, Shlipak, Michael, Hwang, Shih-Jen, Larson, Martin G, OʼDonnell, Christopher J, Upadhyay, Ashish, van Duijn, Cornelia M, Hofman, Albert, Rivadeneira, Fernando, Stricker, Bruno, Uitterlinden, Andre G, Paré, Guillaume, Parker, Alex N, Ridker, Paul M, Siscovick, David S, Gudnason, Vilmundur, Witteman, Jacqueline C, Fox, Caroline S, Coresh, Josef

“…BACKGROUND—Elevated serum urate levels can lead to gout and are associated with cardiovascular risk factors. We performed a genome-wide association study to…”
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Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis by Smith, Nicholas L., Rice, Kenneth M., Bovill, Edwin G., Cushman, Mary, Bis, Joshua C., McKnight, Barbara, Lumley, Thomas, Glazer, Nicole L., van Hylckama Vlieg, Astrid, Tang, Weihong, Dehghan, Abbas, Strachan, David P., O'Donnell, Christopher J., Rotter, Jerome I., Heckbert, Susan R., Psaty, Bruce M., Rosendaal, Frits R.

“…In a recent genome-wide association study, variants in 8 genes were associated with VWF level, a risk factor for venous thrombosis (VT). In an independent,…”
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Common Genetic Variants Associate with Serum Phosphorus Concentration by KESTENBAUM, Bryan, GLAZER, Nicole L, GIEGER, Christian, RIED, Janina S, MEITINGER, Thomas, STROM, Tim M, WICHMANN, H. Erich, CAMPBELL, Harry, HAYWARD, Caroline, RUDAN, Igor, DE BOER, Ian H, PSATY, Bruce M, KÖTTGEN, Anna, RICE, Kenneth M, IDA CHEN, Yii-Der, MAN LI, ARKING, Dan E, BOERWINKLE, Eric, CORESH, Josef, QIONG YANG, LEVY, Daniel, VAN ROOIJ, Frank J. A, DEHGHAN, Abbas, FELIX, Janine F, RIVADENEIRA, Fernando, UITTERLINDEN, André G, HOFMAN, Albert, VAN DUIJN, Cornelia M, SHLIPAK, Michael G, LINDA KAO, W. H, WITTEMAN, Jacqueline C. M, SISCOVICK, David S, FOX, Caroline S, HWANG, Shih-Jen, YONGMEI LIU, LOHMAN, Kurt, KRITCHEVSKY, Stephen B, HAUSMAN, Dorothy B, PETERSEN, Ann-Kristin

“…Phosphorus is an essential mineral that maintains cellular energy and mineralizes the skeleton. Because complex actions of ion transporters and regulatory…”
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Cerivastatin, genetic variants, and the risk of rhabdomyolysis by Marciante, Kristin D, Durda, Jon P, Heckbert, Susan R, Lumley, Thomas, Rice, Ken, McKnight, Barbara, Totah, Rheem A, Tamraz, Bani, Kroetz, Deanna L, Fukushima, Hisayo, Kaspera, Rüdiger, Bis, Joshua C, Glazer, Nicole L, Li, Guo, Austin, Thomas R, Taylor, Kent D, Rotter, Jerome I, Jaquish, Cashell E, Kwok, Pui-Yan, Tracy, Russell P, Psaty, Bruce M

“…OBJECTIVEThe withdrawal of cerivastatin involved an uncommon but serious adverse reaction, rhabdomyolysis. The bimodal response, rhabdomyolysis in a small…”
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