Search Results - "Glaviano, Antonino"
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PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
Published in Molecular cancer (18-08-2023)“…The PI3K/AKT/mTOR (PAM) signaling pathway is a highly conserved signal transduction network in eukaryotic cells that promotes cell survival, cell growth, and…”
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CHK1 inhibitor sensitizes resistant colorectal cancer stem cells to nortopsentin
Published in iScience (25-06-2021)“…Limited therapeutic options are available for advanced colorectal cancer (CRC). Herein, we report that exposure to a neo-synthetic bis(indolyl)thiazole…”
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Targeting Phosphatases and Kinases: How to Checkmate Cancer
Published in Frontiers in cell and developmental biology (28-10-2021)“…Metastatic disease represents the major cause of death in oncologic patients worldwide. Accumulating evidence have highlighted the relevance of a small…”
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Inhibition of the Pim1 oncogene results in diminished visual function
Published in PloS one (26-12-2012)“…Our objective was to profile genetic pathways whose differential expression correlates with maturation of visual function in zebrafish. Bioinformatic analysis…”
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Integrating multiple genome annotation databases improves the interpretation of microarray gene expression data
Published in BMC genomics (20-01-2010)“…The Affymetrix GeneChip is a widely used gene expression profiling platform. Since the chips were originally designed, the genome databases and gene…”
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Mechanisms of sensitivity and resistance to CDK4/CDK6 inhibitors in hormone receptor-positive breast cancer treatment
Published in Drug resistance updates (01-09-2024)“…Cell cycle dysregulation is a hallmark of cancer that promotes eccessive cell division. Cyclin-dependent kinase 4 (CDK4) and cyclin-dependent kinase 6 (CDK6)…”
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Immune Checkpoints in B Cells: Unlocking New Potentials in Cancer Treatment
Published in Advanced science (07-11-2024)“…Abstract B cells are crucial component of humoral immunity, and their role in the tumor immune microenvironment (TME) has garnered significant attention in…”
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Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy
Published in Cancers (04-08-2021)“…Colorectal cancer (CRC) mortality is mainly caused by patient refractoriness to common anti-cancer therapies and consequent metastasis formation. Besides, the…”
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A method for isolation of cone photoreceptors from adult zebrafish retinae
Published in BMC neuroscience (07-11-2016)“…Cone photoreceptors are specialised sensory retinal neurons responsible for photopic vision, colour perception and visual acuity. Retinal degenerative diseases…”
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Acute phase plasma proteins are altered by electroconvulsive stimulation
Published in Journal of psychopharmacology (Oxford) (01-12-2014)“…Electroconvulsive therapy (ECT) is an effective antidepressant treatment, but its molecular mechanisms of action remain to be fully elucidated. To better…”
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