Search Results - "Glaus Garzon, Jesus F"
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CCL2 Is a Vascular Permeability Factor Inducing CCR2-Dependent Endothelial Retraction during Lung Metastasis
Published in Molecular cancer research (01-03-2019)“…Increased levels of the chemokine CCL2 in cancer patients are associated with poor prognosis. Experimental evidence suggests that CCL2 correlates with…”
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Tumor cell endogenous HIF-1α activity induces aberrant angiogenesis and interacts with TRAF6 pathway required for colorectal cancer development
Published in Neoplasia (New York, N.Y.) (01-12-2020)“…•Findings provide evidence that hypoxia response deficient tumors show more functionally perfused vasculature and that TRAF6, an upstream effector of NF-κB, is…”
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Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
Published in Cell host & microbe (13-10-2021)“…Despite overall success, T cell checkpoint inhibitors for cancer treatment are still only efficient in a minority of patients. Recently, intestinal microbiota…”
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Identification of TPM2 and CNN1 as Novel Prognostic Markers in Functionally Characterized Human Colon Cancer-Associated Stromal Cells
Published in Cancers (16-04-2022)“…Stromal infiltration is associated with poor prognosis in human colon cancers. However, the high heterogeneity of human tumor-associated stromal cells (TASCs)…”
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Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IκB
Published in Oncotarget (21-08-2015)“…Two main features common to all solid tumors are tissue hypoxia and inflammation, both of which cause tumor progression, metastasis, therapy resistance and…”
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Abstract 1582: Tumor-associated stromal cells increase malignancy of human colorectal cancers triggering EMT induction
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract In the last decades it has been demonstrated that the stroma surrounding tumor not only provides mechanical support, but profoundly influences the…”
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