Search Results - "Glastras, Sarah"

The Emerging Role of Biomarkers in the Diagnosis of Gestational Diabetes Mellitus by Rodrigo, Natassia, Glastras, Sarah J

“…Gestational diabetes mellitus (GDM) is a common complication of pregnancy; its rising incidence is a result of increased maternal obesity and older maternal…”
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The Role of the Gut Microbiome in Diabetes and Obesity-Related Kidney Disease by Zaky, Amgad, Glastras, Sarah J., Wong, May Y. W., Pollock, Carol A., Saad, Sonia

“…Diabetic kidney disease (DKD) is a progressive disorder, which is increasing globally in prevalence due to the increased incidence of obesity and diabetes…”
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A systematic review of the effects of maternal obesity on neonatal outcomes in women with gestational diabetes by Weir, Tessa L., Majumder, Monica, Glastras, Sarah J.

“…Summary Maternal obesity and gestational diabetes mellitus (GDM) prevalence are increasing, with both conditions associated with adverse neonatal outcomes…”
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Maternal obesity increases the risk of metabolic disease and impacts renal health in offspring by Glastras, Sarah J, Chen, Hui, Pollock, Carol A, Saad, Sonia

“…Obesity, together with insulin resistance, promotes multiple metabolic abnormalities and is strongly associated with an increased risk of chronic disease…”
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Kidney outcomes are altered by preconception weight modulation in rodent mothers with obesity by Rodrigo, Natassia, Chen, Hui, Pollock, Carol A., Glastras, Sarah J.

“…Obesity increases the risk of chronic kidney disease. We have previously demonstrated the benefits of preconception maternal weight loss on fertility and…”
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Preconception weight loss improves fertility and maternal outcomes in obese mice by Rodrigo, Natassia, Chen, Hui, Pollock, Carol A, Glastras, Sarah J

“…Women with obesity have higher incidences of infertility, with longer time to conception and increased risk of pregnancy complications compared to women with…”
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Low-dose hydralazine during gestation reduces renal fibrosis in rodent offspring exposed to maternal high fat diet by Larkin, Benjamin P, Saad, Sonia, Glastras, Sarah J, Nguyen, Long T, Hou, Miao, Chen, Hui, Wang, Rosy, Pollock, Carol A

“…Maternal high fat diet (HFD) promotes chronic kidney disease (CKD) in offspring. This is in accordance with the theory of fetal programming, which suggests…”
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Targeted identification of risk and treatment of diabetic kidney disease by Glastras, Sarah J., Pollock, Carol A.

“…Basic discovery and clinical trials in diabetic kidney disease (DKD) have continued to be reported in 2023 despite the disruption of research activity by…”
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Large-for-Gestational-Age Neonates in Type 1 Diabetes and Pregnancy: Contribution of Factors Beyond Hyperglycemia by McGrath, Rachel T, Glastras, Sarah J, Hocking, Samantha L, Fulcher, Gregory R

“…Despite significant reductions in serious adverse perinatal outcomes for women with type 1 diabetes in pregnancy, the opposite effect has been observed for…”
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Obesity Class Impacts Adverse Maternal and Neonatal Outcomes Independent of Diabetes by Neal, Kirsten, Ullah, Shahid, Glastras, Sarah J

“…Obesity in pregnancy is a known risk factor for adverse maternal and neonatal outcomes. Few studies have compared adverse pregnancy-related outcomes according…”
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DNA methylation and the potential role of demethylating agents in prevention of progressive chronic kidney disease by Larkin, Benjamin P., Glastras, Sarah J., Chen, Hui, Pollock, Carol A., Saad, Sonia

“…ABSTRACT Chronic kidney disease (CKD) is a global epidemic, and its major risk factors include obesity and type 2 diabetes. Obesity not only promotes metabolic…”
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The renal consequences of maternal obesity in offspring are overwhelmed by postnatal high fat diet by Glastras, Sarah J, Chen, Hui, Tsang, Michael, Teh, Rachel, McGrath, Rachel T, Zaky, Amgad, Chen, Jason, Wong, Muh Geot, Pollock, Carol A, Saad, Sonia

“…Developmental programming induced by maternal obesity influences the development of chronic disease in offspring. In the present study, we aimed to determine…”
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Effect of GLP-1 Receptor Activation on Offspring Kidney Health in a Rat Model of Maternal Obesity by Glastras, Sarah J., Chen, Hui, McGrath, Rachel T., Zaky, Amgad A., Gill, Anthony J., Pollock, Carol A., Saad, Sonia

“…Maternal obesity is associated with an increased risk of chronic disease in offspring, including type 2 diabetes (T2D). Exendin-4 (Exd-4) activates the…”
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Editorial: Developmental Programming of Metabolic Diseases by Glastras, Sarah J, Valvi, Damaskini, Bansal, Amita

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Diet Modification before or during Pregnancy on Maternal and Foetal Outcomes in Rodent Models of Maternal Obesity by Rodrigo, Natassia, Saad, Sonia, Pollock, Carol, Glastras, Sarah J

“…The obesity epidemic has serious implications for women of reproductive age; its rising incidence is associated not just with health implications for the…”
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Mouse Models of Diabetes, Obesity and Related Kidney Disease by Glastras, Sarah J, Chen, Hui, Teh, Rachel, McGrath, Rachel T, Chen, Jason, Pollock, Carol A, Wong, Muh Geot, Saad, Sonia

“…Multiple rodent models have been used to study diabetic kidney disease (DKD). The purpose of the present study was to compare models of diabetes and…”
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Maternal Weight Intervention in the Perinatal Period Improves Liver Health in the Offspring of Mothers with Obesity by Purcell, Amanda R, Rodrigo, Natassia, Cao, Qinghua, Joseph, Olivia, Gill, Anthony J, Saad, Sonia, Pollock, Carol A, Glastras, Sarah J

“…Early-life exposure to maternal obesity predisposes offspring to metabolic-associated fatty liver disease (MAFLD). This study aimed to determine if peripartum…”
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Low‐dose hydralazine reduces albuminuria and glomerulosclerosis in a mouse model of obesity‐related chronic kidney disease by Larkin, Benjamin P., Nguyen, Long T., Hou, Miao, Glastras, Sarah J., Chen, Hui, Faiz, Alen, Chen, Jason, Wang, Rosy, Pollock, Carol A., Saad, Sonia

“…Aim To determine, using a mouse model of obesity, whether low‐dose hydralazine prevents obesity‐related chronic kidney disease (CKD). Methods From 8 weeks of…”
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Fasting Glucose Level on the Oral Glucose Tolerance Test Is Associated with the Need for Pharmacotherapy in Gestational Diabetes Mellitus by Rodrigo, Natassia, Randall, Deborah, Al-Hial, Farah Abu, Pak, Kathleen L M, Kim, Alexander Junmo, Glastras, Sarah J

“…Gestational diabetes mellitus (GDM) has a rapidly increasing prevalence, which poses challenges to obstetric care and service provision, with known serious…”
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Comment on Ooi and Wong. Twin Pregnancy With Gestational Diabetes Mellitus: A Double Whammy? Diabetes Care 2018;41:e15-e16 by McGrath, Rachel T, Fulcher, Gregory R, Glastras, Sarah J

“…McGrath et al talk about an article by Ooi and Wong about gestational diabetes mellitus (GDM) in twin pregnancy. They found that women with GDM in twin…”
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