Search Results - "Glass, Pamela J."

Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection by DYALL, Julie, COLEMAN, Christopher M, JOHANSEN, Lisa M, LEAR-ROONEY, Calli M, GLASS, Pamela J, HENSLEY, Lisa E, FRIEMAN, Matthew B, HART, Brit J, VENKATARAMAN, Thiagarajan, HOLBROOK, Michael R, KINDRACHUK, Jason, JOHNSON, Reed F, OLINGER, Gene G, JAHRLING, Peter B, LAIDLAW, Monique

“…Outbreaks of emerging infections present health professionals with the unique challenge of trying to select appropriate pharmacologic treatments in the clinic…”
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Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs by Herring, Shawn, Oda, Jessica M, Wagoner, Jessica, Kirchmeier, Delaney, O'Connor, Aidan, Nelson, Elizabeth A, Huang, Qinfeng, Liang, Yuying, DeWald, Lisa Evans, Johansen, Lisa M, Glass, Pamela J, Olinger, Gene G, Ianevski, Aleksandr, Aittokallio, Tero, Paine, Mary F, Fink, Susan L, White, Judith M, Polyak, Stephen J

“…Neglected diseases caused by arenaviruses such as Lassa virus (LASV) and filoviruses like Ebola virus (EBOV) primarily afflict resource-limited countries,…”
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Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses by Holtsberg, Frederick W, Shulenin, Sergey, Vu, Hong, Howell, Katie A, Patel, Sonal J, Gunn, Bronwyn, Karim, Marcus, Lai, Jonathan R, Frei, Julia C, Nyakatura, Elisabeth K, Zeitlin, Larry, Douglas, Robin, Fusco, Marnie L, Froude, Jeffrey W, Saphire, Erica Ollmann, Herbert, Andrew S, Wirchnianski, Ariel S, Lear-Rooney, Calli M, Alter, Galit, Dye, John M, Glass, Pamela J, Warfield, Kelly L, Aman, M Javad

“…The unprecedented 2014-2015 Ebola virus disease (EVD) outbreak in West Africa has highlighted the need for effective therapeutics against filoviruses…”
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Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein by Keck, Zhen-Yong, Enterlein, Sven G, Howell, Katie A, Vu, Hong, Shulenin, Sergey, Warfield, Kelly L, Froude, Jeffrey W, Araghi, Nazli, Douglas, Robin, Biggins, Julia, Lear-Rooney, Calli M, Wirchnianski, Ariel S, Lau, Patrick, Wang, Yong, Herbert, Andrew S, Dye, John M, Glass, Pamela J, Holtsberg, Frederick W, Foung, Steven K H, Aman, M Javad

“…Filoviruses cause highly lethal viral hemorrhagic fever in humans and nonhuman primates. Current immunotherapeutic options for filoviruses are mostly specific…”
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Therapeutic monoclonal antibody treatment protects nonhuman primates from severe Venezuelan equine encephalitis virus disease after aerosol exposure by Burke, Crystal W, Froude, Jeffery W, Rossi, Franco, White, Charles E, Moyer, Crystal L, Ennis, Jane, Pitt, M Louise, Streatfield, Stephen, Jones, R Mark, Musiychuk, Konstantin, Kervinen, Jukka, Zeitlin, Larry, Yusibov, Vidadi, Glass, Pamela J

“…There are no FDA licensed vaccines or therapeutics for Venezuelan equine encephalitis virus (VEEV) which causes a debilitating acute febrile illness in humans…”
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Defining the Cynomolgus Macaque ( Macaca fascicularis ) Animal Model for Aerosolized Venezuelan Equine Encephalitis: Importance of Challenge Dose and Viral Subtype by Burke, Crystal W, Gardner, Christina L, Goodson, Aimee I, Piper, Ashley E, Erwin-Cohen, Rebecca A, White, Charles E, Glass, Pamela J

“…Venezuelan equine encephalitis virus (VEEV) outbreaks occur sporadically. Additionally, VEEV has a history of development as a biothreat agent. Yet, no…”
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Bivalent single domain antibody constructs for effective neutralization of Venezuelan equine encephalitis by Liu, Jinny L., Zabetakis, Dan, Gardner, Christina L., Burke, Crystal W., Glass, Pamela J., Webb, Emily M., Shriver-Lake, Lisa C., Anderson, George P., Weger-Lucarelli, James, Goldman, Ellen R.

“…Venezuelan equine encephalitis virus (VEEV) is a mosquito borne alphavirus which leads to high viremia in equines followed by lethal encephalitis and lateral…”
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In Silico Screening of Inhibitors of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease by Hu, Xin, Morazzani, Elaine, Compton, Jaimee R, Harmon, Moeshia, Soloveva, Veronica, Glass, Pamela J, Garcia, Andres Dulcey, Marugan, Juan J, Legler, Patricia M

“…The Venezuelan equine encephalitis virus (VEEV) nonstructural protein 2 (nsP2) cysteine protease (EC 3.4.22.B79) is essential for viral replication. High…”
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Efficacy of Western, Eastern, and Venezuelan Equine Encephalitis (WEVEE) Virus-Replicon Particle (VRP) Vaccine against WEEV in a Non-Human Primate Animal Model by Burke, Crystal W., Erwin-Cohen, Rebecca A., Goodson, Aimee I., Wilhelmsen, Catherine, Edmundson, Jennifer A., White, Charles E., Glass, Pamela J.

“…The purpose of this study was to evaluate the effects of the route of administration on the immunogenicity and efficacy of a combined western, eastern, and…”
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Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection by Williamson, Lauren E, Flyak, Andrew I, Kose, Nurgun, Bombardi, Robin, Branchizio, Andre, Reddy, Srikar, Davidson, Edgar, Doranz, Benjamin J, Fusco, Marnie L, Saphire, Erica O, Halfmann, Peter J, Kawaoka, Yoshihiro, Piper, Ashley E, Glass, Pamela J, Crowe, Jr, James E

“…The human B cell response to natural filovirus infections early after recovery is poorly understood. Previous serologic studies suggest that some Ebola virus…”
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Eastern and Venezuelan Equine Encephalitis Viruses Differ in Their Ability To Infect Dendritic Cells and Macrophages: Impact of Altered Cell Tropism on Pathogenesis by GARDNER, Christina L, BURKE, Crystal W, TESFAY, Mulu Z, GLASS, Pamela J, KLIMSTRA, William B, RYMAN, Kate D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Syrian Hamsters Model Does Not Reflect Human-like Disease after Aerosol Exposure to Encephalitic Alphaviruses by Gardner, Christina L, Erwin-Cohen, Rebecca A, Lewis, Bridget S, Bakken, Russell R, Honnold, Shelley P, Glass, Pamela J, Burke, Crystal W

“…Venezuelan (VEE), eastern (EEE), and western (WEE) equine encephalitis viruses are encephalitic New World alphaviruses that cause periodic epizootic and…”
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Human-Like Neutralizing Antibodies Protect Mice from Aerosol Exposure with Western Equine Encephalitis Virus by Burke, Crystal W, Froude, Jeffrey W, Miethe, Sebastian, Hülseweh, Birgit, Hust, Michael, Glass, Pamela J

“…Western equine encephalitis virus (WEEV) causes symptoms in humans ranging from mild febrile illness to life-threatening encephalitis, and no human medical…”
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Preserving Immunogenicity of Lethally Irradiated Viral and Bacterial Vaccine Epitopes Using a Radio- Protective Mn2+-Peptide Complex from Deinococcus by Gaidamakova, Elena K., Myles, Ian A., McDaniel, Dennis P., Fowler, Cedar J., Valdez, Patricia A., Naik, Shruti, Gayen, Manoshi, Gupta, Paridhi, Sharma, Anuj, Glass, Pamela J., Maheshwari, Radha K., Datta, Sandip K., Daly, Michael J.

“…Although pathogen inactivation by γ-radiation is an attractive approach for whole-organism vaccine development, radiation doses required to ensure sterility…”
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Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus by Cong, Yu, Dyall, Julie, Hart, Brit J, DeWald, Lisa Evans, Johnson, Joshua C, Postnikova, Elena, Zhou, Huanying, Gross, Robin, Rojas, Oscar, Alexander, Isis, Josleyn, Nicole, Zhang, Tengfei, Michelotti, Julia, Janosko, Krisztina, Glass, Pamela J, Flint, Mike, McMullan, Laura K, Spiropoulou, Christina F, Mierzwa, Tim, Guha, Rajarshi, Shinn, Paul, Michael, Sam, Klumpp-Thomas, Carleen, McKnight, Crystal, Thomas, Craig, Eakin, Ann E, O'Loughlin, Kathleen G, Green, Carol E, Catz, Paul, Mirsalis, Jon C, Honko, Anna N, Olinger, Jr, Gene G, Bennett, Richard S, Holbrook, Michael R, Hensley, Lisa E, Jahrling, Peter B

“…In the fall of 2014, an international news agency reported that patients suffering from Ebola virus disease (EVD) in Liberia were treated successfully with…”
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Cross-Strain Neutralizing and Protective Monoclonal Antibodies against EEEV or WEEV by Phelps, Amanda L, O'Brien, Lyn M, Ulaeto, David O, Holtsberg, Frederick W, Liao, Grant C, Douglas, Robin, Aman, M Javad, Glass, Pamela J, Moyer, Crystal L, Ennis, Jane, Zeitlin, Larry, Nagata, Les P, Hu, Wei-Gang

“…The three encephalitic alphaviruses, namely, the Venezuelan, eastern, and western equine encephalitis viruses (VEEV, EEEV, and WEEV), are classified by the…”
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The Immune Response to Eastern Equine Encephalitis Virus Acquired Through Organ Transplantation by Raabe, Vanessa, Lai, Lilin, Xu, Yong, Huerta, Chris, Wang, Dongli, Pouch, Stephanie M., Burke, Crystal W., Piper, Ashley E., Gardner, Christina L., Glass, Pamela J., Mulligan, Mark J.

“…The human immune response to eastern equine encephalitis virus (EEEV) infection is poorly characterized due to the rarity of infection. We examined the humoral…”
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Approach to Strain Selection and the Propagation of Viral Stocks for Venezuelan Equine Encephalitis Virus Vaccine Efficacy Testing under the Animal Rule by Rusnak, Janice M, Glass, Pamela J, Weaver, Scott C, Sabourin, Carol L, Glenn, Andrew M, Klimstra, William, Badorrek, Christopher S, Nasar, Farooq, Ward, Lucy A

“…Licensure of a vaccine to protect against aerosolized Venezuelan equine encephalitis virus (VEEV) requires use of the U.S. Food and Drug Administration (FDA)…”
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In Vivo Production of Monoclonal Antibodies by Gene Transfer via Electroporation Protects against Lethal Influenza and Ebola Infections by Andrews, Chasity D, Luo, Yang, Sun, Ming, Yu, Jian, Goff, Arthur J, Glass, Pamela J, Padte, Neal N, Huang, Yaoxing, Ho, David D

“…Monoclonal antibodies (mAbs) have wide clinical utility, but global access is limited by high costs and impracticalities associated with repeated passive…”
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Second generation inactivated eastern equine encephalitis virus vaccine candidates protect mice against a lethal aerosol challenge by Honnold, Shelley P, Bakken, Russell R, Fisher, Diana, Lind, Cathleen M, Cohen, Jeffrey W, Eccleston, Lori T, Spurgers, Kevin B, Maheshwari, Radha K, Glass, Pamela J

“…Currently, there are no FDA-licensed vaccines or therapeutics for eastern equine encephalitis virus (EEEV) for human use. We recently developed several methods…”
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