Search Results - "Glass, CK"

Combinatorial roles of nuclear receptors in inflammation and immunity by Glass, Christopher K, Ogawa, Sumito

“…Members of the nuclear-receptor superfamily have well-documented regulatory effects on inflammatory processes. Recent work has highlighted the roles of…”
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Atherosclerosis: The Road Ahead by Glass, Christopher K., Witztum, Joseph L.

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Topoisomerase IIβ-Mediated dsDNA Break Required for Regulated Transcription by Ju, Bong-Gun, Lunyak, Victoria V, Perissi, Valentina, Garcia-Bassets, Ivan, Rose, David W, Glass, Christopher K, Rosenfeld, Michael G

“…Multiple enzymatic activities are required for transcriptional initiation. The enzyme DNA topoisomerase II associates with gene promoter regions and can…”
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A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ by Fong, Amy L, Ogawa, Sumito, Willson, Timothy M, Rosenfeld, Michael G, Perissi, Valentina, Pascual, Gabriel, Rose, David W, Li, Andrew C, Glass, Christopher K, Gamliel, Amir

“…Peroxisome proliferator-activated receptor-γ (PPAR-γ) has essential roles in adipogenesis and glucose homeostasis, and is a molecular target of…”
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The coregulator exchange in transcriptional functions of nuclear receptors by Glass, C K, Rosenfeld, M G

“…Nuclear receptors (NR) comprise a family of transcription factors that regulate gene expression in a ligand-dependent manner. Members of the NR superfamily…”
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PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis by Li, Andrew C., Glass, Christopher K.

“…The nuclear receptor superfamily is composed of transcription factors that positively and negatively regulate gene expression in response to the binding of a…”
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SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron by Jepsen, Kristen, Solum, Derek, Zhou, Tianyuan, McEvilly, Robert J, Kim, Hyun-Jung, Glass, Christopher K, Hermanson, Ola, Rosenfeld, Michael G

“…A series of transcription factors critical for maintenance of the neural stem cell state have been identified, but the role of functionally important…”
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The macrophage foam cell as a target for therapeutic intervention by Glass, Christopher K, Li, Andrew C

“…Specialized functions of macrophages have evolved to protect the body from infection. However, the same mechanisms that enable phagocytosis of pathogens and…”
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A comprehensive classification system for lipids by Fahy, Eoin, Subramaniam, Shankar, Brown, H Alex, Glass, Christopher K, Merrill, Jr, Alfred H, Murphy, Robert C, Raetz, Christian R H, Russell, David W, Seyama, Yousuke, Shaw, Walter, Shimizu, Takao, Spener, Friedrich, van Meer, Gerrit, VanNieuwenhze, Michael S, White, Stephen H, Witztum, Joseph L, Dennis, Edward A

“…Lipids are produced, transported, and recognized by the concerted actions of numerous enzymes, binding proteins, and receptors. A comprehensive analysis of…”
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Molecular Determinants of Crosstalk between Nuclear Receptors and Toll-like Receptors by Ogawa, Sumito, Lozach, Jean, Benner, Chris, Pascual, Gabriel, Tangirala, Rajendra K., Westin, Stefan, Hoffmann, Alexander, Subramaniam, Shankar, David, Michael, Rosenfeld, Michael G., Glass, Christopher K.

“…Nuclear receptors (NRs) repress transcriptional responses to diverse signaling pathways as an essential aspect of their biological activities, but mechanisms…”
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Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate by Mansson, Robert, Welinder, Eva, Åhsberg, Josefine, Lin, Yin C., Benner, Christopher, Glass, Christopher K., Lucas, Joseph S., Sigvardsson, Mikael, Murre, Cornelis

“…Recent studies have identified a number of transcriptional regulators, including E2A, early B-cell factor 1 (EBF1), FOXO1, and paired box gene 5 (PAX5), that…”
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Coregulator Codes of Transcriptional Regulation by Nuclear Receptors by Rosenfeld, Michael G., Glass, Christopher K.

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A Corepressor/Coactivator Exchange Complex Required for Transcriptional Activation by Nuclear Receptors and Other Regulated Transcription Factors by Perissi, Valentina, Aggarwal, Aneel, Glass, Christopher K, Rose, David W, Rosenfeld, Michael G

“…The mechanisms that control the precisely regulated switch from gene repression to gene activation represent a central question in mammalian development. Here,…”
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Going nuclear in metabolic and cardiovascular disease by Glass, Christopher K

“…Estrogen receptors, PPARs, and liver X receptors are members of the nuclear receptor superfamily of ligand-dependent transcription factors that regulate…”
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PPARγ and PPARδ Negatively Regulate Specific Subsets of Lipopolysaccharide and IFN-γ Target Genes in Macrophages by Welch, John S., Ricote, Mercedes, Akiyama, Taro E., Gonzalez, Frank J., Glass, Christopher K.

“…Natural and synthetic agonists of the peroxisome proliferator-activated receptor γ (PPARγ) regulate adipocyte differentiation, glucose homeostasis, and…”
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Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein by Baek, Sung Hee, Ohgi, Kenneth A., Rose, David W., Koo, Edward H., Glass, Christopher K., Rosenfeld, Michael G.

“…Defining the molecular mechanisms that integrate diverse signaling pathways at the level of gene transcription remains a central issue in biology. Here, we…”
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Nuclear receptor coregulators: multiple modes of modification by Hermanson, Ola, Glass, Christopher K, Rosenfeld, Michael G

“…Many proteins have been characterized as coregulators that can be recruited by DNA-binding nuclear receptors to influence transcriptional regulation. Recent…”
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Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis by Li, Xue, Rosenfeld, Michael G, Ohgi, Kenneth A, Zhang, Jie, Krones, Anna, Bush, Kevin T, Glass, Christopher K, Nigam, Sanjay K, Aggarwal, Aneel K, Maas, Richard, Rose, David W

“…The precise mechanistic relationship between gene activation and repression events is a central question in mammalian organogenesis, as exemplified by the…”
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Peroxisome Proliferator-Activated Receptor γ-Dependent Repression of the Inducible Nitric Oxide Synthase Gene by Li, Mei, Pascual, Gabriel, Glass, Christopher K.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Activating the PARP-1 Sensor Component of the Groucho/ TLE1 Corepressor Complex Mediates a CaMKinase IIδ-Dependent Neurogenic Gene Activation Pathway by Ju, Bong-Gun, Solum, Derek, Song, Eun Joo, Lee, Kong-Joo, Rose, David W., Glass, Christopher K., Rosenfeld, Michael G.

“…Switching specific patterns of gene repression and activation in response to precise temporal/spatial signals is critical for normal development. Here we…”
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