Search Results - "Glasgow, Wayne C"
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CREB-Mediated IL-6 Expression Is Required for 15(S)-Hydroxyeicosatetraenoic Acid–Induced Vascular Smooth Muscle Cell Migration
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-2009)“…OBJECTIVE—Migration of vascular smooth muscle cells (VSMCs) from media to intima is a key event in the pathophysiology of atherosclerosis and restenosis. The…”
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Src-dependent STAT-3-mediated Expression of Monocyte Chemoattractant Protein-1 Is Required for 15(S)-Hydroxyeicosatetraenoic Acid-induced Vascular Smooth Muscle Cell Migration
Published in The Journal of biological chemistry (06-11-2009)“…To understand the role of human 15-lipoxygenase 1 (15-LOX1) in vascular wall remodeling, we have studied the effect of the major 15-LOX1 metabolite of…”
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15(S)-HETE Production in Human Retinal Microvascular Endothelial Cells by Hypoxia: Novel Role for MEK1 in 15(S)-HETE Induced Angiogenesis
Published in Investigative ophthalmology & visual science (01-11-2007)“…To examine for the expression of 15-lipoxygenase 1 (15-LOX1) and 15-LOX2 in human retinal microvascular endothelial cells (HRMVECs) and study the role of…”
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15(S)-Lipoxygenase-2 Mediates Arachidonic Acid-stimulated Adhesion of Human Breast Carcinoma Cells through the Activation of TAK1, MKK6, and p38 MAPK
Published in The Journal of biological chemistry (09-09-2005)“…The dietary cis-polyunsaturated fatty acid, arachidonic acid, stimulates adhesion of metastatic human breast carcinoma cells (MDA-MB-435) to the extracellular…”
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Inhibition of myoblast migration by prostacyclin is associated with enhanced cell fusion
Published in The FASEB journal (01-10-2007)“…Satellite cells are stem cells that are critical for the formation and growth of skeletal muscle during myogenesis. To differentiate and fuse, proliferating…”
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VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection)
Published in Circulation (New York, N.Y.) (28-03-2006)“…The haplotypes in the gene vitamin K epoxide reductase complex subunit 1 (VKORC1) have been found to affect warfarin dose response through effects on the…”
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Arachidonic and Linoleic Acid Metabolism in Mouse Intestinal Tissue: Evidence for Novel Lipoxygenase Activity
Published in Archives of biochemistry and biophysics (01-02-2002)“…Previous studies in our laboratory revealed a high expression of 15-lipoxygenase-1 in human colorectal carcinomas, suggesting the importance of lipoxygenase in…”
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Role of Hydroperoxyeicosatetraenoic Acids in Oxidative Stress-induced Activating Protein 1 (AP-1) Activity
Published in The Journal of biological chemistry (01-11-1996)“…We have previously reported that hydrogen peroxide, an active oxygen species and a cellular oxidant, induces c-Fos and c-Jun mRNA expression and DNA synthesis…”
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Cellular proliferation and lipid metabolism: importance of lipoxygenases in modulating epidermal growth factor-dependent mitogenesis
Published in Cancer and metastasis reviews (01-12-1994)“…In this article we have reviewed and discussed the results of our investigation of lipid metabolites as modulators of epidermal growth factor (EGF) signaling…”
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Expression of Gab1 Lacking the Pleckstrin Homology Domain Is Associated with Neoplastic Progression
Published in Molecular and Cellular Biology (01-10-2001)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of the adhesion of a human breast carcinoma cell line to type IV collagen and vitronectin : Roles for lipoxygenase and protein kinase C
Published in Cancer research (Chicago, Ill.) (01-05-1996)“…We have investigated the regulation of adhesion of metastatic human breast carcinoma cells to various protein substrates in the presence or absence of the…”
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Poxvirus-Induced Alteration of Arachidonate Metabolism
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1993)“…Recent evidence suggests that orthopoxviruses have an obligate requirement for arachidonic acid metabolites during replication in vivo and in vitro. Our report…”
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The Linoleic Acid Metabolite, (13S)-Hydroperoxyoctadecadienoic Acid, Augments the Epidermal Growth Factor Receptor Signaling Pathway by Attenuation of Receptor Dephosphorylation
Published in The Journal of biological chemistry (01-08-1997)“…In Syrian hamster embryo (SHE) fibroblasts, epidermal growth factor receptor (EGFR) tyrosine kinase activity regulates the metabolism of endogenous linoleic…”
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Curcumin suppresses interleukin 1beta-mediated microsomal prostaglandin E synthase 1 by altering early growth response gene 1 and other signaling pathways
Published in The Journal of pharmacology and experimental therapeutics (01-11-2005)“…Curcumin (diferuloylmethane) is one of the phytophenolic compounds found in the turmeric plant with anti-inflammatory and anticarcinogenic activities. One…”
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15S-Lipoxygenase-2 mediates arachidonic acid-stimulated adhesion of human breast carcinoma cells through the activation of TAK1, MKK6, and p38 MAPK
Published in The Journal of biological chemistry (09-09-2005)“…The dietary cis-polyunsaturated fatty acid, arachidonic acid, stimulates adhesion of metastatic human breast carcinoma cells (MDA-MB-435) to the extracellular…”
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Activation of mitogen-activated protein kinases by arachidonic acid and its metabolites in vascular smooth muscle cells
Published in The Journal of biological chemistry (23-12-1994)“…Previous studies from this laboratory and others suggest that arachidonic acid and its metabolites play important roles in a variety of biological processes…”
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Suspected chronic organochlorine pesticide poisoning
Published in Archives of environmental health (01-03-2002)Get more information
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The linoleic acid metabolite, (13S)-hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. Differential response in Syrian hamster embryo tumor suppressor phenotypes
Published in The Journal of biological chemistry (01-08-1997)“…In Syrian hamster embryo (SHE) fibroblasts, epidermal growth factor receptor (EGFR) tyrosine kinase activity regulates the metabolism of endogenous linoleic…”
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Modulation of the epidermal growth factor mitogenic response by metabolites of linoleic and arachidonic acid in Syrian hamster embryo fibroblasts. Differential effects in tumor suppressor gene (+) and (-) phenotypes
Published in The Journal of biological chemistry (25-05-1992)“…Specific metabolites of arachidonic and linoleic acid have been proposed as serving a regulatory function in growth factor signal transduction in fibroblasts…”
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