Search Results - "Gladson, C."

HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells by NATARAJAN, M, STEWART, J. E, GOLEMIS, E. A, PUGACHEVA, E. N, ALEXANDROPOULOS, K, COX, B. D, WANG, W, GRAMMER, J. R, GLADSON, C. L

“…The highly invasive behavior of glioblastoma cells contributes to the morbidity and mortality associated with these tumors. The integrin-mediated adhesion and…”
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Immobilization of Pseudomonas fluorescens lipase on hydrophobic supports and application in biodiesel synthesis by transesterification of vegetable oils in solvent-free systems by Lima, Lionete N, Oliveira, Gladson C, Rojas, Mayerlenis J, Castro, Heizir F, Da Rós, Patrícia C. M, Mendes, Adriano A, Giordano, Raquel L. C, Tardioli, Paulo W

“…This work describes the preparation of biocatalysts for ethanolysis of soybean and babassu oils in solvent-free systems. Polystyrene, Amberlite (XAD-7HP), and…”
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The Extracellular Matrix of Gliomas: Modulation of Cell Function by Gladson, Candece L

“…The ECM of astrocytic tumors promotes and modulates a variety of cell functions, such as cell attachment, migration, proliferation, survival, and signaling…”
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Vitronectin, a Glioma-derived Extracellular Matrix Protein, Protects Tumor Cells from Apoptotic Death by UHM, J. H, DOOLEY, N. P, KYRITSIS, A. P, RAO, J. S, GLADSON, C. L

“…Vitronectin (VN) is an extracellular matrix (ECM) protein, the synthesis of which in vivo by glioma cells correlates with tumor grade. Although the role of VN…”
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Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells by Gladson, C L, Cheresh, D A

“…Glioblastoma multiforme, the most malignant astroglial-derived tumor, grows as an adherent mass and locally invades normal brain. An examination of adult…”
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Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors by Gladson, C L

“…Angiogenesis, which promotes tumor proliferation and invasiveness, is mediated by integrin-dependent cell adhesion mechanisms and requires expression of…”
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p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo by Wang, D, Grammer, J R, Cobbs, C S, Stewart, Jr, J E, Liu, Z, Rhoden, R, Hecker, T P, Ding, Q, Gladson, C L

“…p125 focal adhesion kinase (p125FAK) is a cytoplasmic tyrosine kinase that is activated upon engagement of integrin cell adhesion receptors, and initiates…”
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Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth by MOHAN, P. M, CHINTALA, S. K, KYRITSIS, A. P, RAO, J. S, MOHANAM, S, GLADSON, C. L, EUI SO KIM, GOKASLAN, Z. L, LAKKA, S. S, ROTH, J. A, FANG, B, SAWAYA, R

“…The urokinase-type plasminogen activator (uPA) and uPA receptor (UPAR) play important roles in the proteolytic cascade involved in the invasiveness of gliomas…”
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Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse by Olman, M A, Mackman, N, Gladson, C L, Moser, K M, Loskutoff, D J

“…Bleomycin-induced lung injury is an established murine model of human pulmonary fibrosis. Although procoagulant molecules (e.g., tissue factor [TF]) and…”
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Increased Injury Following Intermittent Fetal Hypoxia-Reoxygenation Is Associated with Increased Free Radical Production in Fetal Rabbit Brain by TAN, SIDHARTHA, ZHOU, FEN, NIELSEN, VANCE G, WANG, ZIWEI, GLADSON, CANDECE L, PARKS, DALE A

“…Hypoxia associated with perinatal events can result in brain damage in the neonate. In labor and eclampsia, hypoxia can be intermittent, which may result in…”
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Up-regulation of urokinase and urokinase receptor genes in malignant astrocytoma by Gladson, CL, Pijuan-Thompson, V, Olman, MA, Gillespie, GY, Yacoub, IZ

“…To understand the role of urokinase (u-PA) and the urokinase receptor (u-PAR) in malignant astrocytoma cell invasion of normal brain, astrocytic expression of…”
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HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells by Natarajan, M, Stewart, J E, Golemis, E A, Pugacheva, E N, Alexandropoulos, K, Cox, B D, Wang, W, Grammer, J R, Gladson, C L

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Glioma migration can be blocked by nontoxic inhibitors of myosin II by GILLESPIE, G. Y, SOROCEANU, L, MANNING, T. J, GLADSON, C. L, ROSENFELD, S. S

“…Anaplastic gliomas are infiltrative tumors, and their ability to migrate through normal brain contributes to their highly malignant behavior. Invasion of brain…”
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Sustained hypoxia-ischemia results in reactive nitrogen and oxygen species production and injury in the premature fetal rabbit brain by SIDHARTHA TAN, FEN ZHOU, NIELSEN, V. G, ZIWEI WANG, GLADSON, C. L, PARKS, D. A

“…Free radical-mediated injury is implicated in hypoxic-ischemic encephalopathy observed in neonates. We investigated in utero free radical production and injury…”
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The frequency of type I heterozygous protein S and protein C deficiency in 141 unrelated young patients with venous thrombosis by Gladson, C L, Scharrer, I, Hach, V, Beck, K H, Griffin, J H

“…The frequency of heterozygous protein C and protein S deficiency, detected by measuring total plasma antigen, in a group (n = 141) of young unrelated patients…”
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Mechanism of Protein C–Dependent Clot Lysis: Role of Plasminogen Activator Inhibitor by Sakata, Yoichi, Loskutoff, David J., Gladson, Candece L., Hekman, Carla M., Griffin, John H.

“…The mechanism by which activated protein C stimulates fibrinolysis was studied in a simple radiolabeled clot lysis assay system containing purified tissue-type…”
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Transcriptional regulation of the human osteopontin promoter : functional analysis and DNA-protein interactions by DONGYAN WANG, YAMAMOTO, Shunsuke, HIJIYA, Naoki, BENVENISTE, Etty N, GLADSON, Candece L

“…Synthesis of cell attachment proteins and cytokines, such as osteopontin (OPN), can promote tumor cell remodeling of the extracellular matrix into an…”
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Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells by SCHRAPPE, M, KLIER, F. G, SPIRO, R. C, WALTZ, T. A, REISFELD, R. A, GLADSON, C. L

“…Human glioblastomas (five of five), the most malignant astroglial-derived tumors, specifically express a chondroitin sulfate proteoglycan that is recognized by…”
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Vitronectin expression in differentiating neuroblastic tumors: integrin alpha v beta 5 mediates vitronectin-dependent adhesion of retinoic-acid- differentiated neuroblastoma cells by Gladson, CL, Dennis, C, Rotolo, TC, Kelly, DR, Grammer, JR

“…The metastatic potential of undifferentiated neuroblastomas is typically lost when differentiation into ganglioneuroblastomas occurs spontaneously or is…”
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Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors by Gladson, C L, Wilcox, J N, Sanders, L, Gillespie, G Y, Cheresh, D A

“…Expression of the vitronectin gene was detected in advanced human astrocytoma by in situ hybridization, whereas vitronectin mRNA was undetectable in low grade…”
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