Search Results - "Gladkikh, Daniil V"

Cholesterol-Containing Nuclease-Resistant siRNA Accumulates in Tumors in a Carrier-free Mode and Silences MDR1 Gene by Chernikov, Ivan V., Gladkikh, Daniil V., Meschaninova, Mariya I., Ven'yaminova, Alya G., Zenkova, Marina A., Vlassov, Valentin V., Chernolovskaya, Elena L.

“…Chemical modifications are an effective way to improve the therapeutic properties of small interfering RNAs (siRNAs), making them more resistant to degradation…”
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Trimeric Small Interfering RNAs and Their Cholesterol-Containing Conjugates Exhibit Improved Accumulation in Tumors, but Dramatically Reduced Silencing Activity by Chernikov, Ivan V, Gladkikh, Daniil V, Karelina, Ulyana A, Meschaninova, Mariya I, Ven'yaminova, Alya G, Vlassov, Valentin V, Chernolovskaya, Elena L

“…Cholesterol derivatives of nuclease-resistant, anti- small-interfering RNAs were designed to contain a 2'-OMe-modified 21-bp siRNA and a 63-bp TsiRNA in order…”
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Influence of the Composition of Cationic Liposomes on the Performance of Cargo Immunostimulatory RNA by Bishani, Ali, Makarova, Darya M, Shmendel, Elena V, Maslov, Mikhail A, Sen‘kova, Aleksandra V, Savin, Innokenty A, Gladkikh, Daniil V, Zenkova, Marina A, Chernolovskaya, Elena L

“…In this study, the impact of different delivery systems on the cytokine-inducing, antiproliferative, and antitumor activities of short immunostimulatory…”
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Folate-Equipped Cationic Liposomes Deliver Anti-MDR1-siRNA to the Tumor and Increase the Efficiency of Chemotherapy by Gladkikh, Daniil V., Sen′kova, Aleksandra V., Chernikov, Ivan V., Kabilova, Tatyana O., Popova, Nelly A., Nikolin, Valery P., Shmendel, Elena V., Maslov, Mikhail A., Vlassov, Valentin V., Zenkova, Marina A., Chernolovskaya, Elena L.

“…In this study, we examined the in vivo toxicity of the liposomes F consisting of 1,26-bis(cholest-5-en-3-yloxycarbonylamino)-7,11,16,20-tetraazahexacosan…”
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The impact of FOXO on dopamine and octopamine metabolism in Drosophila under normal and heat stress conditions by Gruntenko, Nataly E, Adonyeva, Natalya V, Burdina, Elena V, Karpova, Evgenia K, Andreenkova, Olga V, Gladkikh, Daniil V, Ilinsky, Yury Y, Rauschenbach, Inga Yu

“…The forkhead boxO transcription factor (FOXO) is a component of the insulin signalling pathway and plays a role in responding to adverse conditions, such as…”
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Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency by Wood, Mattew J. A., Altman, Sidney

“…The design of modified oligonucleotides that combine in one molecule several therapeutically beneficial properties still poses a major challenge. Recently a…”
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Targeted delivery of nucleic acids into xenograft tumors mediated by novel folate-equipped liposomes by Kabilova, Tatyana O., Shmendel, Elena V., Gladkikh, Daniil V., Chernolovskaya, Elena L., Markov, Oleg V., Morozova, Nina G., Maslov, Mikhail A., Zenkova, Marina A.

“…[Display omitted] Folate receptors (FR) are cellular markers highly expressed in various cancer cells. Here, we report on the synthesis of a novel…”
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Cholesterol-Conjugated Supramolecular Multimeric siRNAs: Effect of siRNA Length on Accumulation and Silencing In Vitro and In Vivo by Chernikov, Ivan V, Ponomareva, Ul'yana A, Meschaninova, Mariya I, Bachkova, Irina K, Teterina, Anna A, Gladkikh, Daniil V, Savin, Innokenty A, Vlassov, Valentin V, Zenkova, Marina A, Chernolovskaya, Elena L

“…Conjugation of small interfering RNA (siRNA) with lipophilic molecules is one of the most promising approaches for delivering siRNA . The rate of molecular…”
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Autocrine-based selection of ligands for personalized CAR-T therapy of lymphoma by Stepanov, Alexey V, Markov, Oleg V, Chernikov, Ivan V, Gladkikh, Daniil V, Zhang, Hongkai, Jones, Teresa, Sen'kova, Alexandra V, Chernolovskaya, Elena L, Zenkova, Marina A, Kalinin, Roman S, Rubtsova, Maria P, Meleshko, Alexander N, Genkin, Dmitry D, Belogurov, Jr, Alexey A, Xie, Jia, Gabibov, Alexander G, Lerner, Richard A

“…We report the development of a novel platform to enhance the efficacy and safety of follicular lymphoma (FL) treatment. Since lymphoma is a clonal malignancy…”
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Effects of the mitochondria-targeted antioxidant SkQ1 on sexually motivated behavior in male rats by Amstislavskaya, Tamara G., Maslova, Larissa N., Gladkikh, Daniil V., Belousova, Irina I., Stefanova, Natalya A., Kolosova, Natalya G.

“…Ample research indicates that age-related neuronal–behavioral decrements are the result of oxidative stress and may be ameliorated by antioxidants. Here we…”
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Effects of the mitochondria-targeted antioxidant SkQ1 on sexually motivated behavior in male rats by AMSTISLAVSKAYA, Tamara G, MASLOVA, Larissa N, GLADKIKH, Daniil V, BELOUSOVA, Irina I, STEFANOVA, Natalya A, KOLOSOVA, Natalya G

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