Search Results - "Gladka, Monika"

From Grafts to Genes: Shaping Heart Care With Next-Generation Therapies by Gladka, Monika M

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Cellular communication in a ‘virtual lab’: going beyond the classical ligand-receptor interaction by Gladka, Monika M

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Scientists on the spot: Relaxing the heart in hypertrophic cardiomyopathy by Gladka, Monika M, van der Velden, Jolanda

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The endothelium as Achilles’ heel in COVID-19 patients by Gladka, Monika M, Maack, Christoph

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Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation by Gladka, Monika M, Molenaar, Bas, de Ruiter, Hesther, van der Elst, Stefan, Tsui, Hoyee, Versteeg, Danielle, Lacraz, Grègory P.A, Huibers, Manon M.H, van Oudenaarden, Alexander, van Rooij, Eva

“…BACKGROUND:Genome-wide transcriptome analysis has greatly advanced our understanding of the regulatory networks underlying basic cardiac biology and mechanisms…”
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Single-Cell RNA Sequencing of the Adult Mammalian Heart—State-of-the-Art and Future Perspectives by Gladka, Monika M.

“…Purpose of the Review Cardiovascular disease remains the leading cause of death worldwide, resulting in cardiac dysfunction and, subsequently, heart failure…”
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Scientists on the Spot: Re-defining atherosclerosis through biobanks by Gladka, Monika M, Pasterkamp, Gerard

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Scientists on the Spot: Re-awakening the heart’s regenerative capacity by Gladka, Monika M, Giacca, Mauro

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Correction to: Single-Cell RNA Sequencing of the Adult Mammalian Heart – State of the Art and Future Perspectives by Gladka, Monika M.

“…A Correction to this paper has been published: https://doi.org/10.1007/s11897-021-00507-0…”
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Cutting a path to effective delivery of genome engineering machinery by Gladka, Monika M., Baker, Andrew H.

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Optimizing the human perinatal progenitor cell secretome for future paracrine therapy to counteract cardiac disease with AmnioSMART: an ERA4Health-funded project by Bollini, Sveva, Parolini, Ornella, Reis, Rui L, Pires, Ricardo A, Sampaolesi, Maurilio, Gladka, Monika M

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Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner by Gladka, Monika M., Kohela, Arwa, Molenaar, Bas, Versteeg, Danielle, Kooijman, Lieneke, Monshouwer-Kloots, Jantine, Kremer, Veerle, Vos, Harmjan R., Huibers, Manon M. H., Haigh, Jody J., Huylebroeck, Danny, Boon, Reinier A., Giacca, Mauro, van Rooij, Eva

“…The disruption in blood supply due to myocardial infarction is a critical determinant for infarct size and subsequent deterioration in function. The…”
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Studying the role of chromatin organization in cardiovascular diseases: future perspectives by Gladka, Monika M, Christoffels, Vincent M

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Midnight snacks might shorten your life: lifespan and healthspan advantages of eating less and at the right time by Gladka, Monika M, Le Couteur, David G, Simpson, Stephen J

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Jumping on base editing to repair the diseased cardiovascular system in vivo by Gladka, Monika M, Baker, Andrew H

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Tomo-Seq Identifies SOX9 as a Key Regulator of Cardiac Fibrosis During Ischemic Injury by Lacraz, Grégory P.A, Junker, Jan Philipp, Gladka, Monika M, Molenaar, Bas, Scholman, Koen T, Vigil-Garcia, Marta, Versteeg, Danielle, de Ruiter, Hesther, Vermunt, Marit W, Creyghton, Menno P, Huibers, Manon M.H, de Jonge, Nicolaas, van Oudenaarden, Alexander, van Rooij, Eva

“…BACKGROUND:Cardiac ischemic injury induces a pathological remodeling response, which can ultimately lead to heart failure. Detailed mechanistic insights into…”
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Gene expression profiling of hypertrophic cardiomyocytes identifies new players in pathological remodelling by Vigil-Garcia, Marta, Demkes, Charlotte J, Eding, Joep E C, Versteeg, Danielle, de Ruiter, Hesther, Perini, Ilaria, Kooijman, Lieneke, Gladka, Monika M, Asselbergs, Folkert W, Vink, Aryan, Harakalova, Magdalena, Bossu, Alexander, van Veen, Toon A B, Boogerd, Cornelis J, van Rooij, Eva

“…Abstract Aims Pathological cardiac remodelling is characterized by cardiomyocyte (CM) hypertrophy and fibroblast activation, which can ultimately lead to…”
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Hypoxia-responsive zinc finger E-box-binding homeobox 2 (ZEB2) regulates a network of calcium-handling genes in the injured heart by Gladka, Monika M, Kohela, Arwa, de Leeuw, Anne E, Molenaar, Bas, Versteeg, Danielle, Kooijman, Lieneke, van Geldorp, Mariska, van Ham, Willem B, Caliandro, Rocco, Haigh, Jody J, van Veen, Toon A B, van Rooij, Eva

“…Intracellular calcium (Ca2+) overload is known to play a critical role in the development of cardiac dysfunction. Despite the remarkable improvement in…”
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AntimiR-34a to Enhance Cardiac Repair After Ischemic Injury by Gladka, Monika M, van Rooij, Eva

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Thymosin β4 and prothymosin α promote cardiac regeneration post-ischaemic injury in mice by Gladka, Monika M, Johansen, Anne Katrine Z, van Kampen, Sebastiaan J, Peters, Marijn M C, Molenaar, Bas, Versteeg, Danielle, Kooijman, Lieneke, Zentilin, Lorena, Giacca, Mauro, van Rooij, Eva

“…Abstract Aims The adult mammalian heart is a post-mitotic organ. Even in response to necrotic injuries, where regeneration would be essential to reinstate…”
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