Search Results - "Gladish, Nicole"

Epigenome-wide association study and epigenetic age acceleration associated with cigarette smoking among Costa Rican adults by Cardenas, Andres, Ecker, Simone, Fadadu, Raj P., Huen, Karen, Orozco, Allan, McEwen, Lisa M., Engelbrecht, Hannah-Ruth, Gladish, Nicole, Kobor, Michael S., Rosero-Bixby, Luis, Dow, William H., Rehkopf, David H.

“…Smoking-associated DNA methylation (DNAm) signatures are reproducible among studies of mostly European descent, with mixed evidence if smoking accelerates…”
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Prenatal exposure to phthalates and peripheral blood and buccal epithelial DNA methylation in infants: An epigenome-wide association study by England-Mason, Gillian, Merrill, Sarah M., Gladish, Nicole, Moore, Sarah R., Giesbrecht, Gerald F., Letourneau, Nicole, MacIsaac, Julia L., MacDonald, Amy M., Kinniburgh, David W., Ponsonby, Anne-Louise, Saffery, Richard, Martin, Jonathan W., Kobor, Michael S., Dewey, Deborah

“…[Display omitted] •Novel study of prenatal exposure to phthalates and infant genome-wide DNA methylation.•Phthalates associated with DNA methylation in 12 CpGs…”
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Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways by Schaffner, Samantha L, Wassouf, Zinah, Lazaro, Diana F, Xylaki, Mary, Gladish, Nicole, Lin, David T S, MacIsaac, Julia, Ramadori, Katia, Hentrich, Thomas, Schulze-Hentrich, Julia M, Outeiro, Tiago F, Kobor, Michael S

“…Parkinson's disease (PD) is a neurological disorder with complex interindividual etiology that is becoming increasingly prevalent worldwide. Elevated…”
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Association between maternal depression during pregnancy and newborn DNA methylation by Drzymalla, Emily, Gladish, Nicole, Koen, Nastassja, Epstein, Michael P., Kobor, Michael S., Zar, Heather J., Stein, Dan J., Hüls, Anke

“…Around 15–65% of women globally experience depression during pregnancy, prevalence being particularly high in low- and middle-income countries. Prenatal…”
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Association between maternal perinatal stress and depression and infant DNA methylation in the first year of life by Abrishamcar, Sarina, Zhuang, Beryl C., Thomas, Mara, Gladish, Nicole, MacIsaac, Julia L., Jones, Meaghan J., Simons, Elinor, Moraes, Theo J., Mandhane, Piush J., Brook, Jeffrey R., Subbarao, Padmaja, Turvey, Stuart E., Chen, Edith, Miller, Gregory E., Kobor, Michael S., Hüls, Anke

“…Maternal stress and depression during pregnancy and the first year of the infant’s life affect a large percentage of mothers. Maternal stress and depression…”
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Multi-Omic Data Integration Allows Baseline Immune Signatures to Predict Hepatitis B Vaccine Response in a Small Cohort by Shannon, Casey P, Blimkie, Travis M, Ben-Othman, Rym, Gladish, Nicole, Amenyogbe, Nelly, Drissler, Sibyl, Edgar, Rachel D, Chan, Queenie, Krajden, Mel, Foster, Leonard J, Kobor, Michael S, Mohn, William W, Brinkman, Ryan R, Le Cao, Kim-Anh, Scheuermann, Richard H, Tebbutt, Scott J, Hancock, Robert E W, Koff, Wayne C, Kollmann, Tobias R, Sadarangani, Manish, Lee, Amy Huei-Yi

“…Vaccination remains one of the most effective means of reducing the burden of infectious diseases globally. Improving our understanding of the molecular basis…”
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Machine Learning-Based Single Cell and Integrative Analysis Reveals That Baseline mDC Predisposition Correlates With Hepatitis B Vaccine Antibody Response by Aevermann, Brian D, Shannon, Casey P, Novotny, Mark, Ben-Othman, Rym, Cai, Bing, Zhang, Yun, Ye, Jamie C, Kobor, Michael S, Gladish, Nicole, Lee, Amy Huei-Yi, Blimkie, Travis M, Hancock, Robert E, Llibre, Alba, Duffy, Darragh, Koff, Wayne C, Sadarangani, Manish, Tebbutt, Scott J, Kollmann, Tobias R, Scheuermann, Richard H

“…Vaccination to prevent infectious disease is one of the most successful public health interventions ever developed. And yet, variability in individual vaccine…”
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Methylation of cysteinyl leukotriene receptor 1 genes associates with lung function in asthmatics exposed to traffic-related air pollution by Rabinovitch, Nathan, Jones, Meaghan J., Gladish, Nicole, Faino, Anna V., Strand, Matthew, Morin, Alexander M., MacIsaac, Julie, Lin, David T. S., Reynolds, Paul R., Singh, Amrit, Gelfand, Erwin W., Kobor, Michael S., Carlsten, Christopher

“…Air pollution is associated with early declines in lung function and increased levels of asthma-related cysteinyl leukotrienes (CysLT) but a biological pathway…”
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Sex-Specific Associations between Prenatal Exposure to Bisphenols and Phthalates and Infant Epigenetic Age Acceleration by England-Mason, Gillian, Merrill, Sarah M, Liu, Jiaying, Martin, Jonathan W, MacDonald, Amy M, Kinniburgh, David W, Gladish, Nicole, MacIsaac, Julia L, Giesbrecht, Gerald F, Letourneau, Nicole, Kobor, Michael S, Dewey, Deborah

“…We examined whether prenatal exposure to two classes of endocrine-disrupting chemicals (EDCs) was associated with infant epigenetic age acceleration (EAA), a…”
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Sex differences in epigenetic age in Mediterranean high longevity regions by Engelbrecht, Hannah-Ruth, Merrill, Sarah M, Gladish, Nicole, MacIsaac, Julie L, Lin, David T S, Ecker, Simone, Chrysohoou, Christina A, Pes, Giovanni M, Kobor, Michael S, Rehkopf, David H

“…Sex differences in aging manifest in disparities in disease prevalence, physical health, and lifespan, where women tend to have greater longevity relative to…”
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CuboCube: Student creation of a cancer genetics e-textbook using open-access software for social learning by Seid-Karbasi, Puya, Ye, Xin C, Zhang, Allen W, Gladish, Nicole, Cheng, Suzanne Y S, Rothe, Katharina, Pilsworth, Jessica A, Kang, Min A, Doolittle, Natalie, Jiang, Xiaoyan, Stirling, Peter C, Wasserman, Wyeth W

“…Student creation of educational materials has the capacity both to enhance learning and to decrease costs. Three successive honors-style classes of…”
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CoMeBack: DNA methylation array data analysis for co-methylated regions by Gatev, Evan, Gladish, Nicole, Mostafavi, Sara, Kobor, Michael S

“…Abstract Motivation High-dimensional DNA methylation (DNAm) array coverage, while sparse in the context of the entire DNA methylome, still constitutes a very…”
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Linking national primary care electronic health records to individual records from the U.S. Census Bureau’s American Community Survey: evaluating the likelihood of linkage based on patient health by Limburg, Aubrey, Gladish, Nicole, Rehkopf, David H, Phillips, Robert L, Udalova, Victoria

“…Abstract Objectives To evaluate the likelihood of linking electronic health records (EHRs) to restricted individual-level American Community Survey (ACS) data…”
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The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells by McEwen, Lisa M., O’Donnell, Kieran J., McGill, Megan G., Edgar, Rachel D., Jones, Meaghan J., MacIsaac, Julia L., Lin, David Tse Shen, Ramadori, Katia, Morin, Alexander, Gladish, Nicole, Garg, Elika, Unternaehrer, Eva, Pokhvisneva, Irina, Karnani, Neerja, Kee, Michelle Z. L., Klengel, Torsten, Adler, Nancy E., Barr, Ronald G., Letourneau, Nicole, Giesbrecht, Gerald F., Reynold, James N., Czamara, Darina, Armstrong, Jeffrey M., Essex, Marilyn J., de Weerth, Carolina, Beijers, Roseriet, Tollenaar, Marieke S., Bradley, Bekh, Jovanovic, Tanja, Ressler, Kerry J., Steiner, Meir, Entringer, Sonja, Wadhwa, Pathik D., Buss, Claudia, Bush, Nicole R., Binder, Elisabeth B., Boyce, Thomas, Meaney, Michael J., Horvath, Steve, Kobor, Michael S.

“…The development of biological markers of aging has primarily focused on adult samples. Epigenetic clocks are a promising tool for measuring biological age that…”
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Methylation risk scores for childhood aeroallergen sensitization: Results from the LISA birth cohort by Kilanowski, Anna, Chen, Junyu, Everson, Todd, Thiering, Elisabeth, Wilson, Rory, Gladish, Nicole, Waldenberger, Melanie, Zhang, Hongmei, Celedón, Juan C., Burchard, Esteban G., Peters, Annette, Standl, Marie, Hüls, Anke

“…Background Epigenomic (e.g., DNA methylation [DNAm]) changes have been hypothesized as intermediate step linking environmental exposures with allergic disease…”
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In-utero exposure to indoor air pollution or tobacco smoke and cognitive development in a South African birth cohort study by Christensen, Grace M., Rowcliffe, Claire, Chen, Junyu, Vanker, Aneesa, Koen, Nastassja, Jones, Meaghan J., Gladish, Nicole, Hoffman, Nadia, Donald, Kirsten A., Wedderburn, Catherine J., Kobor, Michael S., Zar, Heather J., Stein, Dan J., Hüls, Anke

“…There is increasing evidence indicating that air pollution exposure is associated with neuronal damage. Since pregnancy is a critical window of vulnerability,…”
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Paternal adverse childhood experiences: Associations with infant DNA methylation by Merrill, Sarah M., Moore, Sarah R., Gladish, Nicole, Giesbrecht, Gerald F., Dewey, Deborah, Konwar, Chaini, MacIssac, Julia L., Kobor, Michael S., Letourneau, Nicole L.

“…Adverse childhood experiences (ACEs), or cumulative childhood stress exposures, such as abuse, neglect, and household dysfunction, predict later health…”
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Associations of peripheral blood DNA methylation and estimated monocyte proportion differences during infancy with toddler attachment style by Merrill, Sarah M., Gladish, Nicole, Fu, Maggie P., Moore, Sarah R., Konwar, Chaini, Giesbrecht, Gerald F., MacIssac, Julia L., Kobor, Michael S., Letourneau, Nicole L.

“…Attachment is a motivational system promoting felt security to a caregiver resulting in a persistent internal working model of interpersonal behavior…”
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Exposure to childhood abuse is associated with human sperm DNA methylation by Roberts, Andrea L., Gladish, Nicole, Gatev, Evan, Jones, Meaghan J., Chen, Ying, MacIsaac, Julia L., Tworoger, Shelley S., Austin, S. Bryn, Tanrikut, Cigdem, Chavarro, Jorge E., Baccarelli, Andrea A., Kobor, Michael S.

“…Offspring of persons exposed to childhood abuse are at higher risk of neurodevelopmental and physical health disparities across the life course. Animal…”
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Newborn differential DNA methylation and subcortical brain volumes as early signs of severe neurodevelopmental delay in a South African Birth Cohort Study by Hüls, Anke, Wedderburn, Catherine J., Groenewold, Nynke A., Gladish, Nicole, Jones, Meaghan J., Koen, Nastassja, MacIsaac, Julia L., Lin, David T. S., Ramadori, Katia E., Epstein, Michael P., Donald, Kirsten A., Kobor, Michael S., Zar, Heather J., Stein, Dan J.

“…Early detection of neurodevelopmental delay is crucial for intervention and treatment strategies. We analysed associations between newborn DNA methylation…”
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