Search Results - "Gladine, Cecile"

Harmonized procedures lead to comparable quantification of total oxylipins across laboratories by Mainka, Malwina, Dalle, Céline, Pétéra, Mélanie, Dalloux-Chioccioli, Jessica, Kampschulte, Nadja, Ostermann, Annika I., Rothe, Michael, Bertrand-Michel, Justine, Newman, John W., Gladine, Cécile, Schebb, Nils Helge

“…Oxylipins are potent lipid mediators involved in a variety of physiological processes. Their profiling has the potential to provide a wealth of information…”
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Evaluating the role of orange juice, HESPERidin in vascular HEALTH benefits (HESPER-HEALTH study): protocol for a randomised controlled trial by Verny, Marie-Anne, Milenkovic, Dragan, Macian, Nicolas, Pereira, Bruno, Evrard, Rémy, Gilcher, Caroline, Steingass, Christof B, Mosoni, Pascale, Gladine, Cécile, Monfoulet, Laurent-Emmanuel, Schweiggert, Ralf, Pickering, Gisèle, Morand, Christine

“…IntroductionAlthough epidemiological studies associate the consumption of sugary beverages with adverse health effects, human experimental studies have…”
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The Plasma Oxylipin Signature Provides a Deep Phenotyping of Metabolic Syndrome Complementary to the Clinical Criteria by Dalle, Céline, Tournayre, Jérémy, Mainka, Malwina, Basiak-Rasała, Alicja, Pétéra, Mélanie, Lefèvre-Arbogast, Sophie, Dalloux-Chioccioli, Jessica, Deschasaux-Tanguy, Mélanie, Lécuyer, Lucie, Kesse-Guyot, Emmanuelle, Fezeu, Léopold K., Hercberg, Serge, Galan, Pilar, Samieri, Cécilia, Zatońska, Katarzyna, Calder, Philip C., Fiil Hjorth, Mads, Astrup, Arne, Mazur, André, Bertrand-Michel, Justine, Schebb, Nils Helge, Szuba, Andrzej, Touvier, Mathilde, Newman, John W., Gladine, Cécile

“…Metabolic syndrome (MetS) is a complex condition encompassing a constellation of cardiometabolic abnormalities. Oxylipins are a superfamily of lipid mediators…”
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MS-based targeted metabolomics of eicosanoids and other oxylipins: Analytical and inter-individual variabilities by Gladine, Cécile, Ostermann, Annika I., Newman, John W., Schebb, Nils Helge

“…Oxylipins, including the well-known eicosanoids, are potent lipid mediators involved in numerous physiological and pathological processes. Therefore, their…”
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The clinical translation of eicosanoids and other oxylipins, although challenging, should be actively pursued by Gladine, Cécile, Fedorova, Maria

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Oxylipin profiling for clinical research: Current status and future perspectives by Parchem, Karol, Letsiou, Sophia, Petan, Toni, Oskolkova, Olga, Medina, Isabel, Kuda, Ondrej, O'Donnell, Valerie B., Nicolaou, Anna, Fedorova, Maria, Bochkov, Valery, Gladine, Cécile

“…Oxylipins are potent lipid mediators with increasing interest in clinical research. They are usually measured in systemic circulation and can provide a wealth…”
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Eicosanoids and Oxylipin Signature in Hereditary Hemochromatosis Patients Are Similar to Dysmetabolic Iron Overload Syndrome Patients but Are Impacted by Dietary Iron Absorption by Lobbes, Hervé, Dalle, Céline, Pereira, Bruno, Ruivard, Marc, Mazur, Andrzej, Gladine, Cécile

“…Oxylipins are mediators of oxidative stress. To characterize the underlying inflammatory processes and phenotype effect of iron metabolism disorders, we…”
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DHA at nutritional doses restores insulin sensitivity in skeletal muscle by preventing lipotoxicity and inflammation by Capel, Frédéric, Acquaviva, Cécile, Pitois, Elodie, Laillet, Brigitte, Rigaudière, Jean-Paul, Jouve, Chrystèle, Pouyet, Corinne, Gladine, Cècile, Comte, Blandine, Vianey Saban, Christine, Morio, Bèatrice

“…Skeletal muscle plays a major role in the control of whole body glucose disposal in response to insulin stimulus. Excessive supply of fatty acids to this…”
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Stability of oxylipins during plasma generation and long-term storage by Koch, Elisabeth, Mainka, Malwina, Dalle, Céline, Ostermann, Annika I., Rund, Katharina M., Kutzner, Laura, Froehlich, Laura-Fabienne, Bertrand-Michel, Justine, Gladine, Cécile, Schebb, Nils Helge

“…Oxidized unsaturated fatty acids – i.e. eicosanoids and other oxylipins – are lipid mediators involved in the regulation of numerous physiological functions…”
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Obesogenic diet in aging mice disrupts gut microbe composition and alters neutrophil:lymphocyte ratio, leading to inflamed milieu in acute heart failure by Kain, Vasundhara, Van Der Pol, William, Mariappan, Nithya, Ahmad, Aftab, Eipers, Peter, Gibson, Deanna L, Gladine, Cecile, Vigor, Claire, Durand, Thierry, Morrow, Casey, Halade, Ganesh V

“…Calorie-dense obesogenic diet (OBD) is a prime risk factor for cardiovascular disease in aging. However, increasing age coupled with changes in the diet can…”
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Simultaneous quantitative profiling of 20 isoprostanoids from omega-3 and omega-6 polyunsaturated fatty acids by LC–MS/MS in various biological samples by Dupuy, Aude, Le Faouder, Pauline, Vigor, Claire, Oger, Camille, Galano, Jean-Marie, Dray, Cédric, Lee, Jetty Chung-Yung, Valet, Philippe, Gladine, Cécile, Durand, Thierry, Bertrand-Michel, Justine

“…Isoprostanoids are a group of non-enzymatic oxygenated metabolites of polyunsaturated fatty acids. It belongs to oxylipins group, which are important lipid…”
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Bioavailability and antioxidant capacity of plant extracts rich in polyphenols, given as a single acute dose, in sheep made highly susceptible to lipoperoxidation by Gladine, Cécile, Rock, E., Morand, C., Bauchart, D., Durand, D.

“…Plant extracts rich in polyphenols (PERP) could represent interesting alternative antioxidants but their use in ruminants needs further investigation since the…”
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Non-enzymatic cyclic oxygenated metabolites of adrenic, docosahexaenoic, eicosapentaenoic and α-linolenic acids; bioactivities and potential use as biomarkers by Galano, Jean-Marie, Lee, Jetty Chung-Yung, Gladine, Cecile, Comte, Blandine, Le Guennec, Jean-Yves, Oger, Camille, Durand, Thierry

“…Cyclic oxygenated metabolites are formed in vivo through non-enzymatic free radical reaction of n-6 and n-3 polyunsaturated fatty acids (PUFAs) such as…”
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Effect of procyanidin on dietary iron absorption in hereditary hemochromatosis and in dysmetabolic iron overload syndrome: A crossover double-blind randomized controlled trial by Lobbes, Hervé, Gladine, Cécile, Mazur, Andrzej, Pereira, Bruno, Dualé, Christian, Cardot, Jean-Michel, Ruivard, Marc

“…Type I hereditary hemochromatosis (HH) and dysmetabolic iron overload syndrome (DIOS) are the two most prevalent iron overload diseases. Although many food…”
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DHA-derived oxylipins, neuroprostanes and protectins, differentially and dose-dependently modulate the inflammatory response in human macrophages: Putative mechanisms through PPAR activation by Bosviel, Rémy, Joumard-Cubizolles, Laurie, Chinetti-Gbaguidi, Giulia, Bayle, Dominique, Copin, Corinne, Hennuyer, Nathalie, Duplan, Isabelle, Staels, Bart, Zanoni, Giuseppe, Porta, Alessio, Balas, Laurence, Galano, Jean-Marie, Oger, Camille, Mazur, Andrzej, Durand, Thierry, Gladine, Cécile

“…Whereas the anti-inflammatory properties and mechanisms of action of long chain ω3 PUFAs have been abundantly investigated, research gaps remain regarding the…”
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Does iron overload in metabolic syndrome affect macrophage profile? A case control study by Lahaye, Clément, Gladine, Cécile, Pereira, Bruno, Berger, Juliette, Chinetti-Gbaguidi, Giulia, Lainé, Fabrice, Mazur, Andrzej, Ruivard, Marc

“…Dysmetabolic iron overload syndrome (DIOS) is common but the clinical relevance of iron overload is not understood. Macrophages are central cells in iron…”
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Lipid profiling following intake of the omega 3 fatty acid DHA identifies the peroxidized metabolites F4-neuroprostanes as the best predictors of atherosclerosis prevention by Gladine, Cécile, Newman, John W, Durand, Thierry, Pedersen, Theresa L, Galano, Jean-Marie, Demougeot, Céline, Berdeaux, Olivier, Pujos-Guillot, Estelle, Mazur, Andrzej, Comte, Blandine

“…The anti-atherogenic effects of omega 3 fatty acids, namely eicosapentaenoic (EPA) and docosahexaenoic acids (DHA) are well recognized but the impact of…”
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Muscle Loss Associated Changes of Oxylipin Signatures During Biological Aging: An Exploratory Study From the PROOF Cohort by Dalle, Céline, Ostermann, Annika Irmgard, Konrad, Thade, Coudy-Gandilhon, Cécile, Decourt, Alice, Barthélémy, Jean-Claude, Roche, Frédéric, Féasson, Léonard, Mazur, André, Béchet, Daniel, Schebb, Nils Helge, Gladine, Cécile

“…Abstract Characterizations of the multiple mechanisms determining biological aging are required to better understand the etiology and identify early biomarkers…”
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Insight into the contribution of isoprostanoids to the health effects of omega 3 PUFAs by Joumard-Cubizolles, Laurie, Lee, Jetty Chung-Yung, Vigor, Claire, Leung, Ho Hang, Bertrand-Michel, Justine, Galano, Jean-Marie, Mazur, André, Durand, Thierry, Gladine, Cecile

“…[Display omitted] •The health benefits of omega 3 PUFAs are modulated by their oxygenated metabolites.•IsoPs are oxygenated metabolites produced through…”
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Obesogenic diet in aging mice disrupts gut microbe composition and alters neutrophi:lymphocyte ratio, leading to inflamed milieu in acute heart failure by Kain, Vasundhara, Van Der Pol, William, Mariappan, Nithya, Ahmad, Aftab, Eipers, Peter, Gibson, Deanna L., Gladine, Cecile, Vigor, Claire, Durand, Thierry, Morrow, Casey, Halade, Ganesh V.

“…ABSTRACTCalorie‐dense obesogenic diet (OBD) is a prime risk factor for cardiovascular disease in aging. However, increasing age coupled with changes in the…”
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