Search Results - "Gladden, L B"

Lactate metabolism: a new paradigm for the third millennium by Gladden, L. B.

“…For much of the 20th century, lactate was largely considered a dead-end waste product of glycolysis due to hypoxia, the primary cause of the O 2 debt following…”
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Hyperthermia increases exercise-induced oxidative stress by McAnulty, S R, McAnulty, L, Pascoe, D D, Gropper, S S, Keith, R E, Morrow, J D, Gladden, L B

“…The purpose of this investigation was to examine oxidative markers after exercise in a hyperthermic environment (35 degrees C, 70 % RH) (Hot) versus a neutral…”
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Blood volume versus deoxygenated NIRS signal: computational analysis of the effects muscle O 2 delivery and blood volume on the NIRS signals by Koirala, B, Concas, A, Sun, Yi, Gladden, L B, Lai, N

“…Near-infrared spectroscopy (NIRS) signals quantify the oxygenated (Δ ) and deoxygenated (Δ ) heme group concentrations. Δ has been preferred to Δ in evaluating…”
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Blood volume versus deoxygenated NIRS signal: computational analysis of the effects muscle O2 delivery and blood volume on the NIRS signals by Koirala, B, Concas, A, Sun, Yi, Gladden, L B, Lai, N

“…Near-infrared spectroscopy (NIRS) signals quantify the oxygenated (ΔHbMbO2) and deoxygenated (ΔHHbMb) heme group concentrations. ΔHHbMb has been preferred to…”
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Estimation of differential pathlength factor from NIRS measurement in skeletal muscle by Koirala, B., Concas, A., Cincotti, A., Sun, Yi, Hernández, A., Goodwin, M.L., Gladden, L.B., Lai, N.

“…The utilization of continuous wave (CW) near-infrared spectroscopy (NIRS) device to measure non-invasively muscle oxygenation in healthy and disease states is…”
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Effect of Blood Flow on Hemoglobin and Myoglobin Oxygenation in Contracting Muscle Using Near-Infrared Spectroscopy by Koirala, B, Saidel, G M, Hernández, A, Gladden, L B, Lai, N

“…Insufficient O delivery to, and uptake by skeletal muscle can produce mobility limitations for patients with chronic diseases. Near-infrared spectroscopy…”
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Regulation of cellular gas exchange, oxygen sensing, and metabolic control by Clanton, T L, Hogan, M C, Gladden, L B

“…Cells must continuously monitor and couple their metabolic requirements for ATP utilization with their ability to take up O2 for mitochondrial respiration…”
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Lactic Acid: New Roles in a New Millennium by Gladden, L. Bruce

“…The older view of lactic acid (HLa) and hypoxia is correct in the sense that anaerobic glycolysis, HLa production, and HLa accumulation are increased under…”
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Effect of contraction frequency on the contractile and noncontractile phases of muscle venous blood flow by Hogan, Michael C, Grassi, Bruno, Samaja, Michele, Stary, Creed M, Gladden, L. B

“…1 Department of Medicine, University of California, San Diego, La Jolla, California 92093-0623; 2 Department of Health and Human Performance, Auburn…”
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Comparison of the BOD POD with the four-compartment model in adult females by FIELDS, David A, WILSON, G. Dennis, GLADDEN, L. Bruce, HUNTER, Gary R, PASCOE, David D, GORAN, Michael I

“…This study was designed to compare the accuracy and bias in estimates of total body density (Db) by hydrostatic weighing (HW) and the BOD POD, and percent body…”
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L-(+)-lactate infusion into working dog gastrocnemius: no evidence lactate per se mediates VO2 slow component by Poole, D C, Gladden, L B, Kurdak, S, Hogan, M C

“…Constant-load exercise that engenders a sustained lactic acidosis (i.e., above the lactate threshold) is accompanied by a slow component of O2 uptake (VO2)…”
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A patient with acute liver failure and extreme hypoglycaemia with lactic acidosis who was not in a coma: causes and consequences of lactate-protected hypoglycaemia by Oldenbeuving, G, McDonald, J R, Goodwin, M L, Sayilir, R, Reijngoud, D J, Gladden, L B, Nijsten, M W N

“…Lactate can substitute for glucose as a metabolic substrate. We report a patient with acute liver failure who was awake despite a glucose level of 0.7 mmol/l…”
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Net lactate uptake during progressive steady-level contractions in canine skeletal muscle by Gladden, L B

“…The purpose of this study was to determine the changes in net lactate uptake (L) by skeletal muscle with a constant elevated blood lactate concentration during…”
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Muscle as a consumer of lactate by Gladden, L B

“…Historically, muscle has been viewed primarily as a producer of lactate but is now considered also to be a primary consumer of lactate. Among the most…”
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Increased [lactate] in working dog muscle reduces tension development independent of pH by Hogan, M C, Gladden, L B, Kurdak, S S, Poole, D C

“…The purpose of this work was to examine the effect of the lactate ion on the fatigue process in working muscle independent of muscle [H+]. L-(+)-lactate was…”
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Muscle glycogen resynthesis after short term, high intensity exercise and resistance exercise by PASCOE, D. D, GLADDEN, L. B

“…Typical rates of muscle glycogen resynthesis after short term, high intensity exercise (15.1 to 33.6 mmol/kg/h) are much higher than glycogen resynthesis rates…”
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Increased steady-state VO2 and larger O2 deficit with CO2 inhalation during exercise by ØSTERGAARD, L, KJAER, K, JENSEN, K, GLADDEN, L. B, MARTINUSSEN, T, PEDERSEN, P. K

“…To examine whether inhalation of CO(2) -enriched gas would increase steady-state VO(2) during exercise and enlarge O(2) deficit. Ten physically active men…”
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Lactate influx into red blood cells from trained and untrained human subjects by SKELTON, M. S, KREMER, D. E, SMITH, E. W, GLADDEN, L. B

“…The purpose of this study was to compare the fractional contributions of the three pathways of lactate transport (band 3 system, nonionic diffusion, and…”
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Lactate influx into red blood cells of athletic and nonathletic species by Skelton, M S, Kremer, D E, Smith, E W, Gladden, L B

“…Transport of lactate across the erythrocyte membrane proceeds by three distinct pathways: 1) nonionic diffusion of lactic acid, 2) inorganic anion exchange…”
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Bioenergetics of contracting skeletal muscle after partial reduction of blood flow by Hogan, Michael C, Gladden, L. Bruce, Grassi, Bruno, Stary, Creed M, Samaja, Michele

“…1  Department of Medicine, University of California, San Diego, La Jolla, California 92093-0623; 2  Department of Health and Human Performance, Auburn…”
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