Search Results - "Gladbach, Yvonne"
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Identification of novel diabetes impaired miRNA-transcription factor co-regulatory networks in bone marrow-derived Lin-/VEGF-R2+ endothelial progenitor cells
Published in PloS one (11-07-2018)“…Endothelial progenitor cells (EPCs) are a group of rare cells that play an important role in the repair of injured vascular endothelial cells and assist in…”
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In vivo vaccination with cell line-derived whole tumor lysates: neoantigen quality, not quantity matters
Published in Journal of translational medicine (21-10-2020)“…Cancer vaccines provide a complex source of neoantigens. Still, increasing evidence reveals that the neoantigen quality rather than the quantity is predictive…”
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Combined Casein Kinase II inhibition and epigenetic modulation in acute B-lymphoblastic leukemia
Published in BMC cancer (06-03-2019)“…The tumor suppressor protein phosphatase and tensin homolog (PTEN) is a key regulator of the PI3K/AKT pathway which is frequently altered in a variety of…”
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Cellular vaccination of MLH1−/− mice - an immunotherapeutic proof of concept study
Published in Oncoimmunology (04-03-2018)“…Mismatch-repair deficiency (MMR-D) is closely linked to hypermutation and accordingly, high immunogenicity. MMR-D-related tumors thus constitute ideal…”
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Identification of novel diabetes impaired miRNA-transcription factor co-regulatory networks in bone marrow-derived Lin.sup.-/VEGF-R2.sup.+ endothelial progenitor cells
Published in PloS one (11-07-2018)“…Endothelial progenitor cells (EPCs) are a group of rare cells that play an important role in the repair of injured vascular endothelial cells and assist in…”
Get full text
Journal Article -
6
A workflow for the integrative transcriptomic description of molecular pathology and the suggestion of normalizing compounds, exemplified by Parkinson’s disease
Published in Scientific reports (21-05-2018)“…The volume of molecular observations on human diseases in public databases is continuously increasing at accelerating rates. A bottleneck is their…”
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Unraveling the Heterogeneous Mutational Signature of Spontaneously Developing Tumors in MLH1−/− Mice
Published in Cancers (02-10-2019)“…Mismatch repair deficient (MMR-D) tumors exemplify the prototypic hypermutator phenotype. Owing to the high mutation rates, plenty of neo-antigens are present…”
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Molecular Characterization of the Response to Conventional Chemotherapeutics in Pro-B-ALL Cell Lines in Terms of Tumor Relapse
Published in Genes (14-07-2022)“…Little is known about optimally applying chemotherapeutic agents in a specific temporal sequence to rapidly reduce the tumor load and to improve therapeutic…”
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Casein Kinase II Inhibition By CX-4945 and Epigenetic Modulation By Decitabine Demonstrate Significant Antiproliferative Activity As Single Agents As Well As in Combination in Acute B-Lymphoblastic Leukemia Cells
Published in Blood (08-12-2017)“…Introduction: Aberrant PI3K/AKT signaling is frequently observed in B cell precursor acute lymphoblastic leukemia (B-ALL) resulting in increased cell…”
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Nurturing tomorrow's leaders: The ISCB Student Council Symposia in 2018 [version 1; peer review: not peer reviewed]
Published in F1000 research (2019)“…The Student Council of the International Society for Computational Biology (ISCB-SC) is a student-focused organization for researchers from all early career…”
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Global network of computational biology communities: ISCB's Regional Student Groups breaking barriers [version 1; peer review: not peer reviewed]
Published in F1000 research (2019)“…Regional Student Groups (RSGs) of the International Society for Computational Biology Student Council (ISCB-SC) have been instrumental to connect computational…”
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