Search Results - "Glad, Camilla A M"

A polymorphism in the CYP17A1 gene influences the therapeutic response to steroidogenesis inhibitors in Cushing's syndrome by Valassi, Elena, Aulinas, Anna, Glad, Camilla AM, Johannsson, Gudmundur, Ragnarsson, Oskar, Webb, Susan M

“…Summary Context Steroidogenesis inhibitors, such as ketoconazole (KTZ) and metyrapone (MTP), are used to lower hypercortisolism in patients with Cushing's…”
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Relations of Adipose Tissue CIDEA Gene Expression to Basal Metabolic Rate, Energy Restriction, and Obesity: Population-Based and Dietary Intervention Studies by Gummesson, Anders, Jernås, Margareta, Svensson, Per-Arne, Larsson, Ingrid, Glad, Camilla A. M., Schéle, Erik, Gripeteg, Lena, Sjöholm, Kajsa, Lystig, Theodore C., Sjöström, Lars, Carlsson, Björn, Fagerberg, Björn, Carlsson, Lena M. S.

“…Context: Cell death-inducing DNA fragmentation factor-α-like effector A (CIDEA) could be a potential target for the treatment of obesity via the modulation of…”
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The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations by Berryman, Darlene E., Glad, Camilla A. M., List, Edward O., Johannsson, Gudmundur

“…Administration of recombinant human growth hormone (GH) or activation of endogenous GH production exhibits great potential to influence the onset and metabolic…”
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Extracellular water and blood pressure in adults with growth hormone (GH) deficiency: a genotype-phenotype association study by Barbosa, Edna J L, Glad, Camilla A M, Nilsson, Anna G, Bosaeus, Niklas, Nyström, Helena Filipsson, Svensson, Per-Arne, Bengtsson, Bengt-Åke, Nilsson, Staffan, Bosaeus, Ingvar, Boguszewski, Cesar Luiz, Johannsson, Gudmundur

“…Growth hormone deficiency (GHD) in adults is associated with decreased extracellular water volume (ECW). In response to GH replacement therapy (GHRT), ECW…”
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Reverse Feeding Suppresses the Activity of the GH Axis in Rats and Induces a Preobesogenic State by Glad, Camilla A.-M, Kitchen, Edward E. J, Russ, Gemma C, Harris, Sophie M, Davies, Jeffrey S, Gevers, Evelien F, Gabrielsson, Britt G, Wells, Timothy

“…Daytime-only feeding in rats suppresses the GH axis, desynchronizes central and peripheral clock mechanisms, and increases the efficiency of lipid storage in…”
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Genome-wide DNA Methylation Differences in Nonfunctioning Pituitary Adenomas With and Without Postsurgical Progression by Hallen, Tobias, Johannsson, Gudmundur, Dahlen, Rahil, Glad, Camilla A. M, Skoglund, Thomas, Olsson, Daniel S

“…Abstract Context Tumor progression in surgically treated patients with nonfunctioning pituitary adenomas (NFPAs) is associated with excess mortality. Reliable…”
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Expression of GHR and Downstream Signaling Genes in Human Adipose Tissue—Relation to Obesity and Weight Change by Glad, Camilla A M, Svensson, Per-Arne, Nystrom, Fredrik H, Jacobson, Peter, Carlsson, Lena M S, Johannsson, Gudmundur, Andersson-Assarsson, Johanna C

“…Abstract Context GH is a strong regulator of metabolism. In obesity, both GH secretion and adipose tissue GHR gene expression are decreased. More detailed…”
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Identification of human glucocorticoid response markers using integrated multi-omic analysis from a randomized crossover trial by Chantzichristos, Dimitrios, Svensson, Per-Arne, Garner, Terence, Glad, Camilla Am, Walker, Brian R, Bergthorsdottir, Ragnhildur, Ragnarsson, Oskar, Trimpou, Penelope, Stimson, Roland H, Borresen, Stina W, Feldt-Rasmussen, Ulla, Jansson, Per-Anders, Skrtic, Stanko, Stevens, Adam, Johannsson, Gudmundur

“…Glucocorticoids are among the most commonly prescribed drugs, but there is no biomarker that can quantify their action. The aim of the study was to identify…”
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SNPs within the GH-signaling pathway are associated with the early IGF1 response to GH replacement therapy in GHD adults by Glad, Camilla A M, Barbosa, Edna J L, Filipsson Nyström, Helena, Carlsson, Lena M S, Nilsson, Staffan, Nilsson, Anna G, Svensson, Per-Arne, Johannsson, Gudmundur

“…ObjectiveGH-deficient (GHD) adults have reduced serum concentrations of IGF1. GH replacement therapy increases serum IGF1 concentrations, but the…”
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Genotypes associated with lipid metabolism contribute to differences in serum lipid profile of GH-deficient adults before and after GH replacement therapy by Barbosa, Edna J L, Glad, Camilla A M, Nilsson, Anna G, Filipsson Nyström, Helena, Götherström, Galina, Svensson, Per-Arne, Vinotti, Isabela, Bengtsson, Bengt-Åke, Nilsson, Staffan, Boguszewski, Cesar Luiz, Johannsson, Gudmundur

“…ObjectiveGH deficiency (GHD) in adults is associated with an altered serum lipid profile that responds to GH replacement therapy (GHRT). This study evaluated…”
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Influence of the Exon 3-Deleted/Full-Length Growth Hormone (GH) Receptor Polymorphism on the Response to GH Replacement Therapy in Adults with Severe GH Deficiency by Barbosa, Edna J. L., Palming, Jenny, Glad, Camilla A. M., Filipsson, Helena, Koranyi, Josef, Bengtsson, Bengt-Åke, Carlsson, Lena M. S., Boguszewski, Cesar L., Johannsson, Gudmundur

“…Context: There is considerable individual variation in the clinical response to GH replacement therapy in GH deficient (GHD) adults. Useful predictors of…”
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Cell death–inducing DFF45-like effector C is reduced by caloric restriction and regulates adipocyte lipid metabolism by Magnusson, Björn, Gummesson, Anders, Glad, Camilla A.M, Goedecke, Julia H, Jernås, Margareta, Lystig, Theodore C, Carlsson, Björn, Fagerberg, Björn, Carlsson, Lena M.S, Svensson, Per-Arne

“…Abstract Members of the cell death–inducing DFF45-like effector (CIDE) gene family have been shown to regulate lipid metabolism. In this article, we report…”
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Visceral Fat and Novel Biomarkers of Cardiovascular Disease in Patients With Addison’s Disease: A Case-Control Study by Bergthorsdottir, Ragnhildur, Ragnarsson, Oskar, Skrtic, Stanko, Glad, Camilla A M, Nilsson, Staffan, Ross, Ian Louis, Leonsson-Zachrisson, Maria, Johannsson, Gudmundur

“…Abstract Context Patients with Addison’s disease (AD) have increased cardiovascular mortality. Objective To study visceral fat and conventional and exploratory…”
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Reduced DNA methylation and psychopathology following endogenous hypercortisolism – a genome-wide study by Glad, Camilla A. M., Andersson-Assarsson, Johanna C., Berglund, Peter, Bergthorsdottir, Ragnhildur, Ragnarsson, Oskar, Johannsson, Gudmundur

“…Patients with Cushing’s Syndrome (CS) in remission were used as a model to test the hypothesis that long-standing excessive cortisol exposure induces changes…”
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Common Genetic Variants in the Glucocorticoid Receptor and the 11β-Hydroxysteroid Dehydrogenase Type 1 Genes Influence Long-Term Cognitive Impairments in Patients With Cushing's Syndrome in Remission by Ragnarsson, Oskar, Glad, Camilla A.M, Berglund, Peter, Bergthorsdottir, Ragnhildur, Eder, Derek N, Johannsson, Gudmundur

“…Context: Cognitive function is impaired in patients with Cushing's syndrome (CS) in remission. Objective: The objective of the investigation was to study the…”
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MECHANISMS IN ENDOCRINOLOGY: Clinical and pharmacogenetic aspects of the growth hormone receptor polymorphism by Boguszewski, Cesar L, Barbosa, Edna J L, Svensson, Per-Arne, Johannsson, Gudmundur, Glad, Camilla A M

“…Pharmacogenetics aims to maximize the beneficial effects of a medical therapy by identifying genetic finger prints from responders and non-responders and,…”
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Body composition and bone mineral density in women with Cushing's syndrome in remission and the association with common genetic variants influencing glucocorticoid sensitivity by Ragnarsson, Oskar, Glad, Camilla A M, Bergthorsdottir, Ragnhildur, Almqvist, Erik G, Ekerstad, Eva, Widell, Håkan, Wängberg, Bo, Johannsson, Gudmundur

“…ObjectiveAdverse body compositional features and low bone mineral density (BMD) are the characteristic of patients with active Cushing's syndrome (CS). The aim…”
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The GH receptor exon 3 deleted/full-length polymorphism is associated with central adiposity in the general population by Glad, Camilla A M, Carlsson, Lena M S, Melander, Olle, Almgren, Peter, Sjöström, Lars, Nilsson, Staffan, Larsson, Ingrid, Svensson, Per-Arne, Johannsson, Gudmundur

“…ObjectiveTo test the hypothesis that the GH receptor (GHR) exon 3 deleted (d3)/full-length (fl) polymorphism influences anthropometry and body composition in…”
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Pseudoacromegaly: A Differential Diagnostic Problem for Acromegaly With a Genetic Solution by Dahlqvist, Per, Spencer, Rupert, Marques, Pedro, Dang, Mary N, Glad, Camilla A M, Johannsson, Gudmundur, Korbonits, Márta

“…Acromegaly is usually not a difficult condition to diagnose once the possibility of this disease has been raised. However, a few conditions present with some…”
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Rapid and high throughput genotyping of the growth hormone receptor exon 3 deleted/full-length polymorphism using a tagSNP by Glad, Camilla A.M, Johannsson, Gudmundur, Carlsson, Lena M.S, Svensson, Per-Arne

“…Abstract Objective The growth hormone (GH) receptor (GHR) exon 3 deleted/full-length (d3/fl) polymorphism has been suggested to affect GH sensitivity. The…”
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