Search Results - "Glória, Ana Beatriz"
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Clinical networking results in continuous improvement of the outcome of patients with acute promyelocytic leukemia
Published in Blood (19-09-2024)“…•The establishment of a clinical network led to significant and lasting advancements in the treatment outcomes of APL over a span of 15 years.•The overall…”
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Mortality by COVID-19 in adults with acute myeloid leukemia: a survey with hematologists in Brazil
Published in Annals of hematology (01-04-2022)Get full text
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High ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia
Published in Blood (12-11-2015)“…The TP73 gene transcript is alternatively spliced and translated into the transcriptionally active (TAp73) or inactive (ΔNp73) isoforms, with opposite effects…”
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Early death and intracranial hemorrhage prediction in acute promyelocytic leukemia: validation of a risk score in a chemotherapy plus ATRA cohort from an international consortium
Published in Haematologica (Roma) (31-10-2024)“…Not available.Not available…”
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NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia
Published in Scientific reports (25-06-2020)“…Non-T cell activation linker (NTAL) is a lipid raft-membrane protein expressed by normal and leukemic cells and involved in cell signaling. In acute…”
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Systemic mastocytosis associated with acute myeloid leukemia
Published in Annals of hematology (2020)Get full text
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Treatment Outcome of Brazilian Patients with Acute Myeloid Leukemia According to the New European LeukemiaNet Recommendations
Published in Blood (18-11-2011)“…Abstract 3146 Although scarce, the results on the outcome of patients with acute myeloid leukemia (AML) in developing countries point to significant…”
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Treatment Outcome of Acute Myeloid Leukemia Patients From Brazil According to Karyotype, Presence or Not of FLT3-ITD and NPM1 Mutations, and BAALC Gene Expression
Published in Blood (19-11-2010)“…Abstract 3836 Current results regarding AML treatment in developed countries have shown that the estimate five-year overall survival (OS) is around 40–50%. In…”
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De novo acute myeloid leukemia in adults younger than 60 years of age: Socioeconomic aspects and treatment results in a Brazilian university center
Published in Leukemia & lymphoma (01-08-2006)“…We retrospectively studied the outcomes of adults with de novo acute myeloid leukemia treated in a reference center in Brazil and analyzed the association with…”
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Socioeconomic Factors May Select Adults Younger Than 60 Years of Age with “De Novo” Acute Myeloid Leukemia To Receive Intensive Treatment outside a Clinical Trial in Developing Countries. Experience of a Brazilian University Center
Published in Blood (16-11-2004)“…Socioeconomic status (SES) is associated with treatment outcomes of ALL childhood. Whether this factor is associated with outcomes in adults AML in a…”
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Characterization of NPM1, FLT3, and IDH1 mutations in adult patients with acute myeloid leukemia: a Brazilian cohort study
Published in Leukemia & lymphoma (01-12-2016)Get full text
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Imbalanced receptors, gene signatures, and function of NK subsets predicts poor clinical outcomes in AML
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract NK cells mediate anti-leukemic immunosurveillance in AML. We hypothesized that impaired NK cells predict poor outcomes in AML. We analyzed the…”
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Acute promyelocytic leukemia presenting as an extradural mass
Published in Revista brasileira de hematologia e hemoterapia (01-01-2011)“…Acute promyelocytic leukemia is potentially a highly curable type of leukemia that usually presents with pancytopenia, coagulopathies and bleeding. We describe…”
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Real-World Data for FLT3-Mutated Acute Myeloid Leukemia Patients Treated in Resource-Constrained Settings
Published in Blood (02-11-2023)“…Background: Fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) is a well-established prognostic marker in acute myeloid leukemia (AML), whereas…”
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Feasibility and Relevance of Incorporating Genetic Testing By Next-Generation Sequencing for Acute Myeloid Leukemia Patients Treated in Low- and Middle-Income Countries
Published in Blood (02-11-2023)“…Background: The outcome of the treatment for acute myeloid leukemia (AML) in low- and middle-income countries (LMIC) is significantly worse than in high-income…”
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Dysregulated Activating and Inhibitory Receptors on Natural Killer Cells Predicts Immune Escape and Poor Outcomes in Acute Myeloid Leukemia
Published in Blood (15-11-2022)Get full text
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Arsenic Trioxide Abrogate MN1 Mediated RA-Resistance in Acute Promyelocytic Leukemia
Published in Blood (13-11-2019)“…Introduction: Described as a well know marker of worse prognosis in acute myeloid leukemia (AML), MN1 overexpression has been associated with inv(16) or EVI1…”
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Clinical and Functional Studies Reveal That TP73 Isoforms Levels Are Associated with Prognosis and RA-Resistance in Acute Promyelocytic Leukemia
Published in Blood (13-11-2019)“…Background: TP73 isoforms gained particular relevance in acute promyelocytic leukemia (APL) since Bernasola et al (JEM. 2004) demonstrated that TAp73 was…”
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Slit-Robo Pathway Is Clinically Relevant and May Represent a Potential Target in Acute Promyelocytic Leukemia
Published in Blood (29-11-2018)“…Background: The Slit-Robo pathway has been shown to participate in the pathogenesis of several malignant diseases in addition to its physiologic role during…”
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Metformintreatment Overcomes ATRA-Resistance in Acute Promyelocytic Leukemia and Increases FOXO3A Expression
Published in Blood (29-11-2018)“…Introduction:FOXO3A is a transcription factor shown to be involved in all-trans retinoic acid (ATRA)-induced granulocytic differentiation and apoptosis in…”
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