Search Results - "Gkouskou, Kalliopi"
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Polycomb Repressor Complex 2 in Genomic Instability and Cancer
Published in International journal of molecular sciences (30-07-2017)“…Polycomb repressor complexes PRC1 and PRC2 regulate chromatin compaction and gene expression, and are widely recognized for their fundamental contributions to…”
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Epitranscriptomic challenges and promises in metabolic diseases
Published in Metabolism, clinical and experimental (01-07-2022)“…•Epitranscriptomics are involved in metabolic disease development, progression, and complications.•Epitranscriptomic modulators include environmental factors,…”
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Serum Concentrations and Dietary Intake of Vitamin B12 in Children and Adolescents on Metformin: A Case–Control Study
Published in International journal of molecular sciences (20-02-2023)“…The International Society of Pediatric and Adolescent Diabetes (ISPAD) recommends metformin (MET) use for metabolic disturbances and hyperglycemia, either in…”
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Genotype-guided dietary supplementation in precision nutrition
Published in Nutrition reviews (01-11-2021)“…Achieving adequate micronutrient status, while avoiding deficiencies, represents a challenge for people globally. Consequently, many individuals resort to oral…”
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The gut microbiota in mouse models of inflammatory bowel disease
Published in Frontiers in cellular and infection microbiology (2014)“…The intestine and the intestinal immune system have evolved through a symbiotic homeostasis under which a highly diverse microbial flora is maintained in the…”
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A genomics perspective of personalized prevention and management of obesity
Published in Human genomics (29-01-2024)“…This review discusses the landscape of personalized prevention and management of obesity from a nutrigenetics perspective. Focusing on macronutrient tailoring,…”
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To Keto or Not to Keto? A Systematic Review of Randomized Controlled Trials Assessing the Effects of Ketogenic Therapy on Alzheimer Disease
Published in Advances in nutrition (Bethesda, Md.) (01-11-2020)“…Alzheimer disease (AD) is a global health concern with the majority of pharmacotherapy choices consisting of symptomatic treatment. Recently, ketogenic…”
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CYP1A2 polymorphisms modify the association of habitual coffee consumption with appetite, macronutrient intake, and body mass index: results from an observational cohort and a cross-over randomized study
Published in International Journal of Obesity (01-01-2022)“…Background/Objectives Evidence regarding the influence of coffee on appetite and weight control is equivocal and the influence of covariates, such as genetic…”
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Obsessed with Healthy Eating: A Systematic Review of Observational Studies Assessing Orthorexia Nervosa in Patients with Diabetes Mellitus
Published in Nutrients (27-10-2021)“…Orthorexia nervosa (ON) is an unspecified feeding or eating disorder (USFED) characterized by an exaggerated, unhealthy obsession with healthy eating. Τypical…”
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Ceramides in Autoimmune Rheumatic Diseases: Existing Evidence and Therapeutic Considerations for Diet as an Anticeramide Treatment
Published in Nutrients (01-01-2023)“…Autoimmune rheumatic diseases (AIRDs) constitute a set of connective tissue disorders and dysfunctions with akin clinical manifestations and autoantibody…”
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Ageotypes revisited: The brain and central nervous system dysfunction as a major nutritional and lifestyle target for healthy aging
Published in Maturitas (01-04-2023)“…•Biological aging phenotypes related to specific organ/system dysfunction are termed “ageotypes”.•Currently, four ageotypes have been identified based on…”
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COVID-19 enters the expanding network of apolipoprotein E4-related pathologies
Published in Redox biology (01-05-2021)“…COVID-19 incidence and case fatality rates (CFR) differ among ethnicities, stimulating efforts to pinpoint genetic factors that could explain these phenomena…”
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Distinct associations of the Saccharomyces cerevisiae Rad9 protein link Mac1-regulated transcription to DNA repair
Published in Current genetics (01-06-2020)“…While it is known that Sc Rad9 DNA damage checkpoint protein is recruited to damaged DNA by recognizing specific histone modifications, here we report a…”
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Beat the Clock: Assessment of Night Eating Syndrome and Circadian Rhythm in a Sample of Greek Adults
Published in Nutrients (01-01-2024)“…The night eating syndrome (NES) is characterized by excessive food intake during the evening and night hours, with 25% of the daily intake being consumed…”
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Genetically Guided Mediterranean Diet for the Personalized Nutritional Management of Type 2 Diabetes Mellitus
Published in Nutrients (25-01-2021)“…The current consensus for the prevention and management of type 2 diabetes mellitus (T2DM) is that high-quality diets and adherence to a healthy lifestyle…”
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TPL2 kinase is a suppressor of lung carcinogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (16-04-2013)“…Lung cancer is a heterogeneous disease at both clinical and molecular levels, posing conceptual and practical bottlenecks in defining key pathways affecting…”
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SUMOylation is required for optimal TRAF3 signaling capacity
Published in PloS one (18-11-2013)“…TNF receptor-associated factors (TRAFs) are multifunctional adaptor proteins involved in temporal and spatial coordination of signals necessary for normal…”
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Genetically-Guided Medical Nutrition Therapy in Type 2 Diabetes Mellitus and Pre-diabetes: A Series of n -of-1 Superiority Trials
Published in Frontiers in nutrition (Lausanne) (21-02-2022)“…Type 2 diabetes mellitus (T2DM) is a heterogeneous metabolic disorder of multifactorial etiology that includes genetic and dietary influences. By addressing…”
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Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins
Published in The Journal of cell biology (26-12-2011)“…E-cadherin (CDH1) loss occurs frequently in carcinogenesis, contributing to invasion and metastasis. We observed that mouse and human epithelial cell lines…”
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The Niche of n-of-1 Trials in Precision Medicine for Weight Loss and Obesity Treatment: Back to the Future
Published in Current nutrition reports (01-06-2022)“…Purpose of Review The n -of-1 clinical trials are considered the epitome of individualized health care. They are employed to address differences in treatment…”
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