Search Results - "Giusto, Elena"

Brain clearance of protein aggregates: a close-up on astrocytes by Giusti, Veronica, Kaur, Gurkirat, Giusto, Elena, Civiero, Laura

“…Protein misfolding and accumulation defines a prevailing feature of many neurodegenerative disorders, finally resulting in the formation of toxic intra- and…”
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Recent advances in the developmental origin of neuroblastoma: an overview by Ponzoni, Mirco, Bachetti, Tiziana, Corrias, Maria Valeria, Brignole, Chiara, Pastorino, Fabio, Calarco, Enzo, Bensa, Veronica, Giusto, Elena, Ceccherini, Isabella, Perri, Patrizia

“…Neuroblastoma (NB) is a pediatric tumor that originates from neural crest-derived cells undergoing a defective differentiation due to genomic and epigenetic…”
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Neuro-immune interactions of neural stem cell transplants: From animal disease models to human trials by Giusto, Elena, Donegà, Matteo, Cossetti, Chiara, Pluchino, Stefano

“…Stem cell technology is a promising branch of regenerative medicine that is aimed at developing new approaches for the treatment of severely debilitating human…”
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Controlled Liposome Delivery from Chitosan-Based Thermosensitive Hydrogel for Regenerative Medicine by Furlani, Franco, Rossi, Arianna, Grimaudo, Maria Aurora, Bassi, Giada, Giusto, Elena, Molinari, Filippo, Lista, Florigio, Montesi, Monica, Panseri, Silvia

“…This work describes the development of an injectable nanocomposite system based on a chitosan thermosensitive hydrogel combined with liposomes for regenerative…”
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Customized biofilm device for antibiofilm and antibacterial screening of newly developed nanostructured silver and zinc coatings by Ghezzi, Daniele, Boi, Marco, Sassoni, Enrico, Valle, Francesco, Giusto, Elena, Boanini, Elisa, Baldini, Nicola, Cappelletti, Martina, Graziani, Gabriela

“…Bacterial colonisation on implantable device surfaces is estimated to cause more than half of healthcare-associated infections. The application of inorganic…”
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Retinoids Delivery Systems in Cancer: Liposomal Fenretinide for Neuroectodermal-Derived Tumors by Bensa, Veronica, Calarco, Enzo, Giusto, Elena, Perri, Patrizia, Corrias, Maria Valeria, Ponzoni, Mirco, Brignole, Chiara, Pastorino, Fabio

“…Retinoids are a class of natural and synthetic compounds derived from vitamin A. They are involved in several biological processes like embryogenesis,…”
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Derivation of hair-inducing cell from human pluripotent stem cells by Gnedeva, Ksenia, Vorotelyak, Ekaterina, Cimadamore, Flavio, Cattarossi, Giulio, Giusto, Elena, Terskikh, Vasiliy V, Terskikh, Alexey V

“…Dermal Papillae (DP) is a unique population of mesenchymal cells that was shown to regulate hair follicle formation and growth cycle. During development most…”
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PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner by Iannotta, Lucia, Fasiczka, Rachel, Favetta, Giulia, Zhao, Yibo, Giusto, Elena, Dall’Ara, Elena, Wei, Jianning, Ho, Franz Y., Ciriani, Claudia, Cogo, Susanna, Tessari, Isabella, Iaccarino, Ciro, Liberelle, Maxime, Bubacco, Luigi, Taymans, Jean-Marc, Manzoni, Claudia, Kortholt, Arjan, Civiero, Laura, Hilfiker, Sabine, Lu, Michael L., Greggio, Elisa

“…P21 activated kinase 6 (PAK6) is a serine-threonine kinase with physiological expression enriched in the brain and overexpressed in a number of human tumors…”
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Graphene Oxide Nanoplatforms to Enhance Cisplatin-Based Drug Delivery in Anticancer Therapy by Giusto, Elena, Žárská, Ludmila, Beirne, Darren Fergal, Rossi, Arianna, Bassi, Giada, Ruffini, Andrea, Montesi, Monica, Montagner, Diego, Ranc, Vaclav, Panseri, Silvia

“…Chemotherapeutics such as platinum-based drugs are commonly used to treat several cancer types, but unfortunately, their use is limited by several side…”
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From the identification of actionable molecular targets to the generation of faithful neuroblastoma patient-derived preclinical models by Capasso, Mario, Brignole, Chiara, Lasorsa, Vito A, Bensa, Veronica, Cantalupo, Sueva, Sebastiani, Enrico, Quattrone, Alessandro, Ciampi, Eleonora, Avitabile, Marianna, Sementa, Angela R, Mazzocco, Katia, Cafferata, Barbara, Gaggero, Gabriele, Vellone, Valerio G, Cilli, Michele, Calarco, Enzo, Giusto, Elena, Perri, Patrizia, Aveic, Sanja, Fruci, Doriana, Tondo, Annalisa, Luksch, Roberto, Mura, Rossella, Rabusin, Marco, De Leonardis, Francesco, Cellini, Monica, Coccia, Paola, Iolascon, Achille, Corrias, Maria V, Conte, Massimo, Garaventa, Alberto, Amoroso, Loredana, Ponzoni, Mirco, Pastorino, Fabio

“…Neuroblastoma (NB) represents the most frequent and aggressive form of extracranial solid tumor of infants. Although the overall survival of patients with NB…”
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Antitumor activity of the investigational B7-H3 antibody-drug conjugate, vobramitamab duocarmazine, in preclinical models of neuroblastoma by Brignole, Chiara, Calarco, Enzo, Bensa, Veronica, Giusto, Elena, Perri, Patrizia, Ciampi, Eleonora, Corrias, Maria Valeria, Astigiano, Simonetta, Cilli, Michele, Loo, Derik, Bonvini, Ezio, Pastorino, Fabio, Ponzoni, Mirco

“…Introduction B7-H3 is a potential target for pediatric cancers, including neuroblastoma (NB). Vobramitamab duocarmazine (also referred to as MGC018 and herein…”
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Nucleolin expression has prognostic value in neuroblastoma patients by Cangelosi, Davide, Brignole, Chiara, Bensa, Veronica, Tamma, Roberto, Malaguti, Fabiana, Carlini, Barbara, Giusto, Elena, Calarco, Enzo, Perri, Patrizia, Ribatti, Domenico, Fonseca, Nuno André, Moreira, Joao Nuno, Eva, Alessandra, Amoroso, Loredana, Conte, Massimo, Garaventa, Alberto, Sementa, Angela Rita, Corrias, Maria Valeria, Ponzoni, Mirco, Pastorino, Fabio

“…Neuroblastoma (NB) represents the most frequent form of extra-cranial solid tumour of infants, responsible for 15% of childhood cancer deaths. Nucleolin (NCL)…”
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Investigation on the future of work: the impact of innovative strategies in a post pandemic scenario by Marco Puliti, Elena Di Giusto, Viola Papetti, Federica Montana

“…In the following research work, an experiment of guided innovation is presented. The context is the Innovation for Change (I4C) program, in which a group of…”
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O13 JAK inhibitors to restore skin barrier function in ARCI by Giusto, Elena, Enjalbert, Florence, Rognoni, Emanuel , Caley, Matthew, O’Toole, Edel 

“…Abstract The autosomal recessive congenital ichthyoses (ARCI) are a group of chronic conditions where there is unmet therapeutic need. Harlequin ichthyosis…”
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P10 Janus kinase inhibitors to restore skin barrier function in a mouse model of Harlequin ichthyosis by Giusto, Elena, Jones, Eleri, Enjalbert, Florence, Ahmed, Abubkr, Caley, Matthew, Rognoni, Emanuel, O’Toole, Edel

“…Abstract Introduction and aims The autosomal recessive congenital ichthyoses (ARCIs) are a group of chronic conditions where there is unmet therapeutic need…”
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Recent Advances and Challenges in Gene Delivery Mediated by Polyester-Based Nanoparticles by Piperno, Anna, Sciortino, Maria Teresa, Giusto, Elena, Montesi, Monica, Panseri, Silvia, Scala, Angela

“…Gene therapy is a promising approach for the treatment of several diseases, such as chronic or viral infections, inherited disorders, and cancer. The cellular…”
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Sequence Learning Induces Selectivity to Multiple Task Parameters in Mouse Somatosensory Cortex by Bale, Michael R., Bitzidou, Malamati, Giusto, Elena, Kinghorn, Paul, Maravall, Miguel

“…Sequential temporal ordering and patterning are key features of natural signals, used by the brain to decode stimuli and perceive them as sensory objects. To…”
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Parkinson’s Disease–Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance by Streubel-Gallasch, Linn, Giusti, Veronica, Sandre, Michele, Tessari, Isabella, Plotegher, Nicoletta, Giusto, Elena, Masato, Anna, Iovino, Ludovica, Battisti, Ilaria, Arrigoni, Giorgio, Shimshek, Derya, Greggio, Elisa, Tremblay, Marie-Eve, Bubacco, Luigi, Erlandsson, Anna, Civiero, Laura

“…Parkinson’s disease (PD) is a neurodegenerative, progressive disease without a cure. To prevent PD onset or at least limit neurodegeneration, a better…”
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Three-dimensional printed polycaprolactone-microcrystalline cellulose scaffolds by Alemán-Domínguez, Maria Elena, Giusto, Elena, Ortega, Zaida, Tamaddon, Maryam, Benítez, Antonio Nizardo, Liu, Chaozong

“…Microcrystalline cellulose (MCC) is proposed in this study as an additive in polycaprolactone (PCL) matrices to obtain three-dimensional (3D) printed scaffolds…”
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Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson’s disease by Iovino, Ludovica, Giusti, Veronica, Pischedda, Francesca, Giusto, Elena, Plotegher, Nicoletta, Marte, Antonella, Battisti, Ilaria, Di Iacovo, Angela, Marku, Algerta, Piccoli, Giovanni, Bandopadhyay, Rina, Perego, Carla, Bonifacino, Tiziana, Bonanno, Giambattista, Roseti, Cristina, Bossi, Elena, Arrigoni, Giorgio, Bubacco, Luigi, Greggio, Elisa, Hilfiker, Sabine, Civiero, Laura

“…The Excitatory Amino Acid Transporter 2 (EAAT2) accounts for 80% of brain glutamate clearance and is mainly expressed in astrocytic perisynaptic processes…”
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