Search Results - "Giusti, Raffaele"
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Gut metabolomics profiling of non-small cell lung cancer (NSCLC) patients under immunotherapy treatment
Published in Journal of translational medicine (03-02-2020)“…Despite the efficacy of immune checkpoint inhibitors (ICIs) only the 20-30% of treated patients present long term benefits. The metabolic changes occurring in…”
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Cancer care during the spread of coronavirus disease 2019 (COVID-19) in Italy: young oncologists’ perspective
Published in ESMO open (01-03-2020)“…Click here to listen to the Podcast…”
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Correlations Between the Immune-related Adverse Events Spectrum and Efficacy of Anti-PD1 Immunotherapy in NSCLC Patients
Published in Clinical lung cancer (01-07-2019)“…Immune-related adverse events (irAEs) developed during immunotherapy with anti-PD-1 agents, could be a predictive surrogate marker of clinical benefit in…”
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A nomogram to predict survival in non-small cell lung cancer patients treated with nivolumab
Published in Journal of translational medicine (27-03-2019)“…The advent of immune checkpoint inhibitors (ICIs) has considerably expanded the armamentarium against non-small cell lung cancer (NSCLC) contributing to…”
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Knowledge and attitudes of Italian medical oncologists and palliative care physicians toward medical use of cannabis in cancer care: a national survey
Published in Supportive care in cancer (01-12-2021)“…Purpose Despite advances in supportive care, cancer-related symptoms tend to be persistent regardless of cancer type, stage of disease, or treatment received…”
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Management of overlapping immune-related myocarditis, myositis, and myasthenia in a young patient with advanced NSCLC: a case report
Published in Frontiers in oncology (11-10-2024)“…Immunotherapy is increasingly used in advanced non-small-cell lung cancer (NSCLC), offering a significant anti-tumor response, as well as causing rising…”
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Tryptophan Catabolism as Immune Mechanism of Primary Resistance to Anti-PD-1
Published in Frontiers in immunology (07-07-2020)“…Clinical trials showed that only a subset of patients benefits from immunotherapy, suggesting the need to identify new predictive biomarker of resistance…”
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Baseline BMI and BMI variation during first line pembrolizumab in NSCLC patients with a PD-L1 expression ≥ 50%: a multicenter study with external validation
Published in Journal for immunotherapy of cancer (01-10-2020)“…BackgroundThe association between obesity and outcomes in patients receiving programmed death-1/programmed death ligand-1 (PD-L1) checkpoint inhibitors has…”
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Clinical outcomes of NSCLC patients experiencing early immune-related adverse events to PD-1/PD-L1 checkpoint inhibitors leading to treatment discontinuation
Published in Cancer Immunology, Immunotherapy (01-04-2022)“…Background The prognostic relevance of early immune-related adverse events (irAEs) in patients affected by non-small cell lung cancer (NSCLC) upon…”
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Clinical and psychometric validation of the BreSAS questionnaire module for symptom assessment among breast cancer survivors
Published in Supportive care in cancer (01-03-2020)“…Background The large number of women surviving many years post breast cancer (BC) diagnosis has heightened interest in studying long-term effects of cancer on…”
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PD-1/PD-L1 checkpoint inhibitors during late stages of life: an ad-hoc analysis from a large multicenter cohort
Published in Journal of translational medicine (24-06-2021)“…The favourable safety profile and the increasing confidence with immune checkpoint inhibitors (ICIs) might have boosted their prescription in frail patients…”
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Statins and immunotherapy: Togetherness makes strength The potential effect of statins on immunotherapy for NSCLC
Published in Cancer reports (01-08-2021)“…Background Recent researches suggested that statins, beside their role in inhibiting endogenous cholesterol synthesis and in cardiovascular prevention, could…”
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The Agnostic Role of Site of Metastasis in Predicting Outcomes in Cancer Patients Treated with Immunotherapy
Published in Vaccines (Basel) (28-04-2020)“…Immune checkpoint inhibitors have revolutionized treatment and outcome of melanoma and many other solid malignancies including non-small cell lung cancer…”
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Multidisciplinary approach, continuous care and opioid management in cancer pain: case series and review of the literature
Published in Drugs in Context (11-04-2023)“…Underlying cancer pain has heterogenous aetiologies and mechanisms. It requires detailed and comprehensive pain assessment, combined with personalized…”
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Smoking status during first‐line immunotherapy and chemotherapy in NSCLC patients: A case–control matched analysis from a large multicenter study
Published in Thoracic cancer (01-03-2021)“…Background Improved outcome in tobacco smoking patients with non‐small cell lung cancer (NSCLC) following immunotherapy has previously been reported. However,…”
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Knowledge and Attitudes of Young Italian Medical Oncologists Toward the Approach and Treatment of Pain: No Changes, Despite the Law
Published in Pain medicine (Malden, Mass.) (01-09-2017)Get full text
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High Prevalence and Early Occurrence of Skeletal Complications in EGFR Mutated NSCLC Patients With Bone Metastases
Published in Frontiers in oncology (12-11-2020)“…The prevalence of Skeletal Related Adverse Events (SREs) in EGFR mutated non-small cell lung cancer (NSCLC) patients with bone metastases, treated with modern…”
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Comparing efficacy and safety of upfront treatment strategies for anaplastic lymphoma kinase-positive non-small cell lung cancer: a network meta-analysis
Published in Exploration of targeted anti-tumor therapy (2023)“…This article is based on our previous research, which was presented as a post at the Congress Aiom 2022 Congress and published in as Conference Abstract ( …”
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High familial burden of cancer correlates with improved outcome from immunotherapy in patients with NSCLC independent of somatic DNA damage response gene status
Published in Journal of hematology and oncology (21-01-2022)“…Family history of cancer (FHC) is a hallmark of cancer risk and an independent predictor of outcome, albeit with uncertain biologic foundations. We previously…”
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INfluenza Vaccine Indication During therapy with Immune checkpoint inhibitors: a multicenter prospective observational study (INVIDIa-2)
Published in Journal for immunotherapy of cancer (01-05-2021)“…BackgroundUntil now, no robust data supported the efficacy, safety and recommendation for influenza vaccination in patients with cancer receiving immune…”
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