Search Results - "Giusti, Humberto"
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Clinical investigation of intestinal fatty acid-binding protein (I-FABP) as a biomarker of SARS-CoV-2 infection
Published in International journal of infectious diseases (01-12-2021)“…SARS-CoV-2 exhibits tropism for the gastrointestinal tract; however, lesions in enterocytes and their correlation with disease severity and patient prognosis…”
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Behavioral, Ventilatory and Thermoregulatory Responses to Hypercapnia and Hypoxia in the Wistar Audiogenic Rat (WAR) Strain
Published in PloS one (05-05-2016)“…We investigated the behavioral, respiratory, and thermoregulatory responses elicited by acute exposure to both hypercapnic and hypoxic environments in Wistar…”
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Serotonergic neurons in the nucleus raphe obscurus contribute to interaction between central and peripheral ventilatory responses to hypercapnia
Published in Pflügers Archiv (01-09-2011)“…Serotonergic (5-HT) neurons in the nucleus raphe obscurus (ROb) are involved in the respiratory control network. However, it is not known whether ROb 5-HT…”
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Parasympathetic activation by pyridostigmine on chemoreflex sensitivity in heart-failure rats
Published in Autonomic neuroscience (01-12-2013)“…Abstract We evaluated the effects of parasympathetic activation by pyridostigmine (PYR) on chemoreflex sensitivity in a rat model of heart failure (HF rats)…”
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Hemodynamic and ventilatory response to different levels of hypoxia and hypercapnia in carotid body-denervated rats
Published in Clinics (São Paulo, Brazil) (01-01-2013)“…Chemoreceptors play an important role in the autonomic modulation of circulatory and ventilatory responses to changes in arterial O2 and/or CO2. However,…”
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Cholecystokinin Modulates the Mucosal Inflammatory Response and Prevents the Lipopolysaccharide-Induced Intestinal Epithelial Barrier Dysfunction
Published in Shock (Augusta, Ga.) (01-02-2020)“…ABSTRACTThe intestinal mucosa plays a critical role in the organism, acting as an interface between the lamina propria and the harmful antigens in the lumen…”
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Immune-mediated impairment of tonic immobility defensive behavior in an experimental model of colonic inflammation
Published in Pflügers Archiv (01-11-2024)“…Ulcerative colitis has been associated with psychological distress and an aberrant immune response. The immunomodulatory role of systemic cytokines produced…”
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Dexamethasone Prevents Lipopolysaccharide-Induced Epithelial Barrier Dysfunction in Rat Ileum
Published in Shock (Augusta, Ga.) (01-03-2018)“…Inflammatory mediators have been postulated as elementary inducing factors to the disruption of the intestinal tight junctions (TJ) and consequently, gut…”
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Buccal jet streaming and dead space determination in the South American lungfish, Lepidosiren paradoxa
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-09-2019)“…The “jet stream” model predicts an expired flow within the dorsal part of the buccal cavity with small air mixing during buccal pump ventilation, and has been…”
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Role of hydrogen sulfide (H2S) on the ventilatory responses to hypercapnia
Published in The FASEB journal (01-04-2013)“…Abstract only Hydrogen sulfide (H2S), an endogenous gasotransmitter, is predominantly produced by the enzyme cystathionine‐β‐synthase (CBS) within the central…”
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Effects of aerial hypoxia and temperature on pulmonary breathing pattern and gas exchange in the South American lungfish, Lepidosiren paradoxa
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-05-2017)“…The South American lungfish Lepidosiren paradoxa is an obligatory air-breathing fish possessing well-developed bilateral lungs, and undergoing seasonal changes…”
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Central leptin replacement enhances chemorespiratory responses in leptin-deficient mice independent of changes in body weight
Published in Pflügers Archiv (01-08-2012)“…Previous studies showed that leptin-deficient (ob/ob) mice develop obesity and impaired ventilatory responses to CO 2 . In this study, we examined if leptin…”
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Breathing pattern, pulmonary and intrabuccal gases of the South American lungfish Lepidosiren paradoxa
Published in The FASEB journal (01-04-2011)“…Genetic and physiological studies favor the lungfish as a probable sister group to the land vertebrates (Tetrapoda), and some fossil evidence is also…”
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Acute effects of temperature and hypercarbia on cutaneous and branchial gas exchange in the South American lungfish, Lepidosiren paradoxa
Published in Journal of thermal biology (01-01-2017)“…The South American lungfish, Lepidosiren paradoxa inhabits seasonal environments in the Central Amazon and Paraná-Paraguay basins that undergo significant…”
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Sepsis 2016 Paris: Paris, France. 6-8 December 2016
Published in Critical care (London, England) (06-12-2016)Get full text
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Role of serotonergic neurons in the caudal medullary raphe (ROb) on ventilatory and thermoregulatory responses to hypercapnia
Published in The FASEB journal (01-04-2011)“…Medullary raphe (MR) serotoninergic (5‐HT) neurons exert an important role on breathing and thermoregulation. However, the role of caudal MR, specifically…”
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Serotonergic neurons in the nucleus raphé obscurus are not involved in the ventilatory and thermoregulatory responses to hypoxia in adult rats
Published in Respiratory physiology & neurobiology (15-06-2013)“…Highlights • Medullary raphe (MR) is an important part of central respiratory network. • Literature describes difference between rostral and caudal MR on…”
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The breathing pattern and the ventilatory response to aquatic and aerial hypoxia and hypercarbia in the frog Pipa carvalhoi
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-07-2012)“…Anuran amphibians are known to exhibit an intermittent pattern of pulmonary ventilation and to exhibit an increased ventilatory response to hypoxia and…”
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Purinergic transmission in the rostral but not caudal medullary raphe contributes to the hypercapnia-induced ventilatory response in unanesthetized rats
Published in Respiratory physiology & neurobiology (15-10-2012)“…Highlights ► The medullary raphe (MR) is an important site for central chemoreception. ► ATP signalling has been implicated in CO2 /pH sensitivity. ► We have…”
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Blood gases and cardiovascular shunt in the South American lungfish ( Lepidosiren paradoxa ) during normoxia and hyperoxia
Published in Respiratory physiology & neurobiology (31-08-2010)“…Abstract The South American lungfish ( Lepidosiren paradoxa ) has an arterial P O 2 ( P a O 2 ) as high as 70–100 mm Hg, corresponding to Hb–O2 saturations…”
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