Search Results - "Giuliano, Chiara"
-
1
Addictive behaviour in experimental animals: prospects for translation
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19-03-2018)“…Since the introduction of intravenous drug self-administration methodology over 50 years ago, experimental investigation of addictive behaviour has delivered…”
Get full text
Journal Article -
2
The role of the opioid system in binge eating disorder
Published in CNS spectrums (01-12-2015)“…Binge eating disorder is characterized by excessive, uncontrollable consumption of palatable food within brief periods of time. Excessive intake of palatable…”
Get full text
Journal Article -
3
Withdrawal from escalated cocaine self-administration impairs reversal learning by disrupting the effects of negative feedback on reward exploitation: a behavioral and computational analysis
Published in Neuropsychopharmacology (New York, N.Y.) (01-12-2019)“…Addiction is regarded as a disorder of inflexible choice with behavior dominated by immediate positive rewards over longer-term negative outcomes. However, the…”
Get full text
Journal Article -
4
Basolateral and central amygdala differentially recruit and maintain dorsolateral striatum-dependent cocaine-seeking habits
Published in Nature communications (14-12-2015)“…In the development of addiction, drug seeking becomes habitual and controlled by drug-associated cues, and the neural locus of control over behaviour shifts…”
Get full text
Journal Article -
5
Correction: Withdrawal from escalated cocaine self-administration impairs reversal learning by disrupting the effects of negative feedback on reward exploitation: a behavioral and computational analysis
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text
Journal Article -
6
Alcohol-Preferring Rats Show Goal Oriented Behaviour to Food Incentives but Are Neither Sign-Trackers Nor Impulsive
Published in PloS one (22-06-2015)“…Drug addiction is often associated with impulsivity and altered behavioural responses to both primary and conditioned rewards. Here we investigated whether…”
Get full text
Journal Article -
7
Correction: Alcohol-Preferring Rats Show Goal Oriented Behaviour to Food Incentives but Are Neither Sign-Trackers Nor Impulsive
Published in PloS one (24-07-2015)Get full text
Journal Article -
8
Compulsive Alcohol Seeking Results from a Failure to Disengage Dorsolateral Striatal Control over Behavior
Published in The Journal of neuroscience (27-02-2019)“…The acquisition of drug, including alcohol, use is associated with activation of the mesolimbic dopamine system. However, over the course of drug exposure the…”
Get full text
Journal Article -
9
Fine-tuning Muscarinic Cholinergic Transmission in Alcohol Use Disorder
Published in Biological psychiatry (1969) (15-12-2020)Get full text
Journal Article -
10
Addictive behaviour in experimental animals: prospects for translation
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19-03-2018)“…Since the introduction of intravenous drug self-administration methodology over 50 years ago, experimental investigation of addictive behaviour has delivered…”
Get full text
Journal Article -
11
Evidence for a Long-Lasting Compulsive Alcohol Seeking Phenotype in Rats
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2018)“…Excessive drinking to intoxication is the major behavioral characteristic of those addicted to alcohol but it is not the only one. Indeed, individuals addicted…”
Get full text
Journal Article -
12
Individual differences in the engagement of habitual control over alcohol seeking predict the development of compulsive alcohol seeking and drinking
Published in Addiction biology (01-11-2021)“…Excessive drinking is an important behavioural characteristic of alcohol addiction, but not the only one. Individuals addicted to alcohol crave alcoholic…”
Get full text
Journal Article -
13
Negative Urgency Exacerbates Relapse to Cocaine Seeking After Abstinence
Published in Biological psychiatry (1969) (15-06-2022)“…The mechanisms through which drug-cue–induced negative affective states are involved in relapse have not been defined. We tested the hypothesis that in…”
Get full text
Journal Article -
14
The development of compulsive coping behavior depends on dorsolateral striatum dopamine-dependent mechanisms
Published in Molecular psychiatry (01-11-2023)“…Humans greatly differ in how they cope with stress, a natural behavior learnt through negative reinforcement. Some individuals engage in displacement…”
Get full text
Journal Article -
15
Inhibition of Opioid Transmission at the μ-Opioid Receptor Prevents Both Food Seeking and Binge-Like Eating
Published in Neuropsychopharmacology (New York, N.Y.) (01-11-2012)“…Endogenous opioids, and in particular μ-opioid receptors, have been linked to hedonic and rewarding mechanisms engaged during palatable food intake. The aim of…”
Get full text
Journal Article -
16
Environment‐dependent behavioral traits and experiential factors shape addiction vulnerability
Published in The European journal of neuroscience (01-03-2021)“…The transition from controlled drug use to drug addiction depends on an interaction between a vulnerable individual, their environment and a drug. Here we…”
Get full text
Journal Article -
17
The uncompetitive N-methyl-D-aspartate antagonist memantine reduces binge-like eating, food-seeking behavior, and compulsive eating: role of the nucleus accumbens shell
Published in Neuropsychopharmacology (New York, N.Y.) (13-03-2015)“…Binge-eating disorder is characterized by excessive, uncontrollable consumption of palatable food within brief periods of time. The role of the glutamatergic…”
Get full text
Journal Article -
18
-
19
Pituitary adenylate cyclase-activating polypeptide type 1 receptor within the nucleus accumbens core mediates excessive alcohol drinking in alcohol-preferring rats
Published in Neuropharmacology (01-07-2022)“…Alcohol use disorders (AUD) have a strong component of heritability; however, the neurobiological mechanisms mediating the propensity to consume excessive…”
Get full text
Journal Article -
20
Attenuation of cocaine and heroin seeking by μ-opioid receptor antagonism
Published in Psychopharmacology (01-05-2013)“…Rationale Evidence has implicated the endogenous opioids, in particular μ-opioid receptors, in emotional behavior and regulation of reward circuits, especially…”
Get full text
Journal Article