Search Results - "Giuliani, Nicola"
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Estimating uptake and internal transport dynamics of irrigation water in apple trees using deuterium-enriched water
Published in Agricultural water management (01-11-2023)“…With future climatic scenarios foreseeing increased crop water demands and reduced irrigation water availability, a deeper knowledge on the dynamics of water…”
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2
Automatic Age Estimation and Majority Age Classification From Multi-Factorial MRI Data
Published in IEEE journal of biomedical and health informatics (01-07-2019)“…Age estimation from radiologic data is an important topic both in clinical medicine as well as in forensic applications, where it is used to assess unknown…”
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3
CD38: A Target for Immunotherapeutic Approaches in Multiple Myeloma
Published in Frontiers in immunology (28-11-2018)“…Multiple Myeloma (MM) is a hematological cancer characterized by proliferation of malignant plasma cells in the bone marrow (BM). MM represents the second most…”
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4
Multiple myeloma-derived exosomes are enriched of amphiregulin (AREG) and activate the epidermal growth factor pathway in the bone microenvironment leading to osteoclastogenesis
Published in Journal of hematology and oncology (08-01-2019)“…Multiple myeloma (MM) is a clonal plasma cell malignancy associated with osteolytic bone disease. Recently, the role of MM-derived exosomes in the…”
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5
Editorial: Immunotherapy in Multiple Myeloma
Published in Frontiers in immunology (14-08-2019)Get full text
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The Metabolic Features of Osteoblasts: Implications for Multiple Myeloma (MM) Bone Disease
Published in International journal of molecular sciences (01-03-2023)“…The study of osteoblast (OB) metabolism has recently received increased attention due to the considerable amount of energy used during the bone remodeling…”
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7
Multiple myeloma bone disease: pathophysiology of osteoblast inhibition
Published in Blood (15-12-2006)“…Multiple myeloma (MM) is a plasma cell malignancy characterized by a high capacity to induce osteolytic bone lesions. Bone destruction in MM results from…”
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Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target
Published in Blood (04-08-2016)“…The importance of glutamine (Gln) metabolism in multiple myeloma (MM) cells and its potential role as a therapeutic target are still unknown, although it has…”
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Oncolytic Virotherapy and Microenvironment in Multiple Myeloma
Published in International journal of molecular sciences (24-02-2021)“…Multiple myeloma (MM) is a hematologic malignancy characterized by the accumulation of bone marrow (BM) clonal plasma cells, which are strictly dependent on…”
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10
Role of Galectins in Multiple Myeloma
Published in International journal of molecular sciences (17-12-2017)“…Galectins are a family of lectins that bind β-galactose-containing glycoconjugates and are characterized by carbohydrate-recognition domains (CRDs). Galectins…”
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Adenosine Generated in the Bone Marrow Niche Through a CD38-Mediated Pathway Correlates with Progression of Human Myeloma
Published in Molecular medicine (Cambridge, Mass.) (01-01-2016)“…Human myeloma cells express CD38 at high levels and grow in hypoxic niches inside the bone marrow. Myeloma cells respond to hypoxia with metabolic changes…”
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12
Oncolytic viruses: a potential breakthrough immunotherapy for multiple myeloma patients
Published in Frontiers in immunology (30-10-2024)“…Oncolytic virotherapy represents an innovative and promising approach for the treatment of cancer, including multiple myeloma (MM), a currently incurable…”
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13
ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma
Published in Cancer cell (10-07-2017)“…Amplification of 1q21 occurs in approximately 30% of de novo and 70% of relapsed multiple myeloma (MM) and is correlated with disease progression and drug…”
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14
CD14+CD16+ monocytes are involved in daratumumab‐mediated myeloma cells killing and in anti‐CD47 therapeutic strategy
Published in British journal of haematology (01-08-2020)“…Summary A deep elucidation of the mechanisms of action of anti‐CD38 monoclonal antibodies (mAbs), such as daratumumab (DARA), is required to identify patients…”
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15
Drip irrigation frequency leads to plasticity in root water uptake by apple trees
Published in Agricultural water management (01-06-2024)“…Stable isotopes of hydrogen and oxygen are used in agriculture to investigate the water sources used by crops. Yet, isotopic research on irrigated orchards is…”
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16
Mechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone Remodeling
Published in BioMed research international (01-01-2015)“…Multiple myeloma (MM) is characterized by a high capacity to induce alterations in the bone remodeling process. The increase in osteoclastogenesis and the…”
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17
The Proteasome and Myeloma-Associated Bone Disease
Published in Calcified tissue international (01-02-2018)“…Bone disease is the hallmark of multiple myeloma (MM), a hematological malignancy characterized by osteolytic lesions due to a severe uncoupled and unbalanced…”
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The Circular Life of Human CD38: From Basic Science to Clinics and Back
Published in Molecules (Basel, Switzerland) (21-10-2020)“…Monoclonal antibodies (mAbs) were initially considered as a possible "magic bullet" for in vivo elimination of tumor cells. mAbs represented the first step:…”
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A Simplified SARS-CoV-2 Pseudovirus Neutralization Assay
Published in Vaccines (Basel) (15-04-2021)“…COVID-19 is an ongoing pandemic caused by the highly infectious coronavirus SARS-CoV-2 that is engaging worldwide scientific research to find a timely and…”
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Molecular Features of the Mesenchymal and Osteoblastic Cells in Multiple Myeloma
Published in International journal of molecular sciences (07-12-2022)“…Multiple myeloma (MM) is a monoclonal gammopathy characterized by biological heterogeneity and unregulated proliferation of plasma cells (PCs) in bone marrow…”
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