Search Results - "Giulia, Fornasa"

Organ-specific protection mediated by cooperation between vascular and epithelial barriers by Spadoni, Ilaria, Fornasa, Giulia, Rescigno, Maria

“…Key Points The classical concept of immune privilege as an exclusion of immune cells has been extended to include sites of immune tolerance induction, such as…”
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Dichotomy of short and long thymic stromal lymphopoietin isoforms in inflammatory disorders of the bowel and skin by Fornasa, Giulia, PhD, Tsilingiri, Katerina, PhD, Caprioli, Flavio, MD, PhD, Botti, Fiorenzo, MD, Mapelli, Marina, PhD, Meller, Stephan, MD, Kislat, Andreas, MSc, Homey, Bernhard, MD, Di Sabatino, Antonio, MD, Sonzogni, Angelica, MD, Viale, Giuseppe, MD, PhD, Diaferia, Giuseppe, PhD, Gori, Alessandro, PhD, Longhi, Renato, PhD, Penna, Giuseppe, MSc, Rescigno, Maria, PhD

“…Background Thymic stromal lymphopoietin (TSLP) is a cytokine with pleiotropic functions in the immune system. It has been associated with allergic reactions in…”
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Macrophage plasticity in experimental atherosclerosis by Khallou-Laschet, Jamila, Varthaman, Aditi, Fornasa, Giulia, Compain, Caroline, Gaston, Anh-Thu, Clement, Marc, Dussiot, Michaël, Levillain, Olivier, Graff-Dubois, Stéphanie, Nicoletti, Antonino, Caligiuri, Giuseppina

“…As in human disease, macrophages (MØ) are central players in the development and progression of experimental atherosclerosis. In this study we have evaluated…”
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Thymic Stromal Lymphopoietin: To Cut a Long Story Short by Tsilingiri, Katerina, Fornasa, Giulia, Rescigno, Maria

“…Thymic stromal lymphopoietin (TSLP) was identified more than 20 years ago as a secreted factor of a mouse thymic stromal cell line; later, a human orthologue…”
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CD31 is a key coinhibitory receptor in the development of immunogenic dendritic cells by Clement, Marc, Fornasa, Giulia, Guedj, Kevin, Mkaddem, Sanae Ben, Gaston, Anh-Thu, Khallou-Laschet, Jamila, Morvan, Marion, Nicoletti, Antonino, Caligiuri, Giuseppina

“…CD31 is a transhomophilic tyrosine-based inhibitory motif receptor and is expressed by both dendritic cells (DCs) and T lymphocytes. Previous studies have…”
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TCR stimulation drives cleavage and shedding of the ITIM receptor CD31 by Fornasa, Giulia, Groyer, Emilie, Clement, Marc, Dimitrov, Jordan, Compain, Caroline, Gaston, Anh-Thu, Varthaman, Aditi, Khallou-Laschet, Jamila, Newman, Debra K, Graff-Dubois, Stéphanie, Nicoletti, Antonino, Caligiuri, Giuseppina

“…CD31 is a transmembrane molecule endowed with T cell regulatory functions owing to the presence of 2 immunotyrosine-based inhibitory motifs. For reasons not…”
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BNT162b2 vaccine induces antibody release in saliva: a possible role for mucosal viral protection? by Darwich, Abbass, Pozzi, Chiara, Fornasa, Giulia, Lizier, Michela, Azzolini, Elena, Spadoni, Ilaria, Carli, Francesco, Voza, Antonio, Desai, Antonio, Ferrero, Carlo, Germagnoli, Luca, Mantovani, Alberto, Rescigno, Maria, Alessio, Aghemo, Clement, Anfray, Salvatore, Badalamenti, Cristina, Belgiovine, Alice, Bertocchi, Sara, Bombace, Paola, Brescia, Francesca, Calcaterra, Michela, Calvi, Assunta, Cancellara, Arianna, Capucetti, Claudia, Carenza, Sara, Carloni, Silvia, Carnevale, Valentina, Cazzetta, Maurizio, Cecconi, Michele, Ciccarelli, Nicolò, Coianiz, Abbass, Darwich, Lleo De Nalda, Ana, Federica, De Paoli, Rachele, Di Donato, Elisabeth, Digifico, Barbara, Durante, Maria, Farina Floriana, Valentina, Ferrari, Giulia, Fornasa, Sara, Franzese, Antonio, Gil Gomez, Silvia, Giugliano, Gomes, Ana Rita, Michela, Lizier, Antonino, Lo Cascio, Alessia, Melacarne, Alessandro, Mozzarelli, Ilaria, My, Bianca, Oresta, Fabio, Pasqualini, Anna, Pastò, Erica, Pelamatti, Chiara, Perucchini, Chiara, Pozzi, Valeria, Rimoldi, Monica, Rimoldi, Alice, Scarpa, Carlo, Selmi, Alessandra, Silvestri, Marina, Sironi, Ilaria, Spadoni, Salvatore, Spano', Gianmarco, Spata, Domenico, Supino, Paolo, Tentorio, Aldo, Ummarino, Sonia, Valentino, Antonio, Voza, Elisa, Zaghi, Veronica, Zanon

“…Vaccination against an airborne pathogen is very effective if it induces also the development of mucosal antibodies that can protect against infection. The…”
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Physiological induction of regulatory Qa-1-restricted CD8+ T cells triggered by endogenous CD4+ T cell responses by Varthaman, Aditi, Clement, Marc, Khallou-Laschet, Jamila, Fornasa, Giulia, Gaston, Anh-Thu, Dussiot, Michael, Caligiuri, Giuseppina, Cantor, Harvey, Kaveri, Srinivas, Nicoletti, Antonino

“…T cell-dependent autoimmune diseases are characterized by the expansion of T cell clones that recognize immunodominant epitopes on the target antigen. As a…”
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Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth by Zagato, Elena, Pozzi, Chiara, Bertocchi, Alice, Schioppa, Tiziana, Saccheri, Fabiana, Guglietta, Silvia, Fosso, Bruno, Melocchi, Laura, Nizzoli, Giulia, Troisi, Jacopo, Marzano, Marinella, Oresta, Bianca, Spadoni, Ilaria, Atarashi, Koji, Carloni, Sara, Arioli, Stefania, Fornasa, Giulia, Asnicar, Francesco, Segata, Nicola, Guglielmetti, Simone, Honda, Kenya, Pesole, Graziano, Vermi, William, Penna, Giuseppe, Rescigno, Maria

“…The microbiota has been shown to promote intestinal tumourigenesis, but a possible anti-tumourigenic effect has also been postulated. Here, we demonstrate that…”
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Macrophage CD31 Signaling in Dissecting Aortic Aneurysm by Andreata, Francesco, Syvannarath, Varouna, Clement, Marc, Delbosc, Sandrine, Guedj, Kevin, Fornasa, Giulia, Khallou-Laschet, Jamila, Morvan, Marion, Even, Guillaume, Procopio, Emanuele, Gaston, Anh-Thu, Le Borgne, Marie, Deschamps, Lydia, Nicoletti, Antonino, Caligiuri, Giuseppina

“…The authors recently found that a CD31 agonist peptide reaches macrophages in injured aortas and exerts beneficial effects on apolipoprotein E-knockout (Apo…”
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M1 macrophages act as LTβR-independent lymphoid tissue inducer cells during atherosclerosis-related lymphoid neogenesis by Guedj, Kevin, Khallou-Laschet, Jamila, Clement, Marc, Morvan, Marion, Gaston, Anh-Thu, Fornasa, Giulia, Dai, Jianping, Gervais-Taurel, Marianne, Eberl, Gerard, Michel, Jean-Baptiste, Caligiuri, Giuseppina, Nicoletti, Antonino

“…The goal of this study was to characterize the role of inflammatory macrophages in the induction of the vascular smooth muscle cell (VSMC)-mediated formation…”
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Abnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease by Biancheri, Paolo, Di Sabatino, Antonio, Rescigno, Maria, Giuffrida, Paolo, Fornasa, Giulia, Tsilingiri, Katerina, Pender, Sylvia L F, Papadia, Cinzia, Wood, Eleanor, Pasini, Alessandra, Ubezio, Cristina, Vanoli, Alessandro, Forbes, Alastair, MacDonald, Thomas T, Corazza, Gino R

“…The short isoform of thymic stromal lymphopoietin (TSLP), a cytokine constitutively expressed by epithelial cells, is crucial in preserving immune tolerance in…”
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Thymic Stromal Lymphopoietin: To Cut a Long Story ShortSummary by Katerina Tsilingiri, Giulia Fornasa, Maria Rescigno

“…Thymic stromal lymphopoietin (TSLP) was identified more than 20 years ago as a secreted factor of a mouse thymic stromal cell line; later, a human orthologue…”
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Biomimetic superabsorbent hydrogel acts as a gut protective dynamic exoskeleton improving metabolic parameters and expanding A. muciniphila by Silvestri, Alessandra, Gil-Gomez, Antonio, Vitale, Milena, Braga, Daniele, Demitri, Christian, Brescia, Paola, Madaghiele, Marta, Spadoni, Ilaria, Jones, Bryan, Fornasa, Giulia, Mouries, Juliette, Carloni, Sara, Lizier, Michela, Romero-Gomez, Manuel, Penna, Giuseppe, Sannino, Alessandro, Rescigno, Maria

“…The rising prevalence of obesity and metabolic disorders worldwide highlights the urgent need to find new long-term and clinically meaningful weight-loss…”
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Abstract 1277: Unveiling the impact of intratumoral microbiota in the treatment efficacy of soft tissue sarcoma by Tiraboschi, Luca, Braga, Daniele, Melacarne, Alessia, Ferrari, Valentina, Vella, Gerlanda, Mozzarelli, Alessandro, Lo Cascio, Antonino, Fornasa, Giulia, Lizier, Michela, Carloni, Sara, Martano, Giuseppe, Timo, Sara, Bernardinello, Alessandro, Renne, Salvatore Lorenzo, Cananzi, Ferdinando, Bertuzzi, Alessia, Penna, Giuseppe, Rescigno, Maria

“…Abstract Tumor resident microbiota is an emerging component of the tumor microenvironment with unclear biological function. Among all microorganisms harbored…”
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Innate and adaptive immunity in self-reported nonceliac gluten sensitivity versus celiac disease by Di Sabatino, Antonio, Giuffrida, Paolo, Fornasa, Giulia, Salvatore, Chiara, Vanoli, Alessandro, Naviglio, Samuele, De Leo, Luigina, Pasini, Alessandra, De Amici, Mara, Alvisi, Costanza, Not, Tarcisio, Rescigno, Maria, Corazza, Gino Roberto

“…Abstract Background Immune mechanisms have been implicated in nonceliac gluten sensitivity (NCGS), a condition characterized by intestinal and/or…”
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Mucosal Overexpression of Thymic Stromal Lymphopoietin and Proinflammatory Cytokines in Patients With Autoimmune Atrophic Gastritis by Lenti, Marco Vincenzo, Facciotti, Federica, Miceli, Emanuela, Vanoli, Alessandro, Fornasa, Giulia, Lahner, Edith, Spadoni, Ilaria, Giuffrida, Paolo, Arpa, Giovanni, Pasini, Alessandra, Rovedatti, Laura, Caprioli, Flavio, Travelli, Cristina, Lattanzi, Georgia, Conti, Laura, Klersy, Catherine, Vecchi, Maurizio, Paulli, Marco, Annibale, Bruno, Corazza, Gino Roberto, Rescigno, Maria, Di Sabatino, Antonio

“…INTRODUCTIONThe immune mechanisms underlying human autoimmune atrophic gastritis (AAG) are poorly understood. We sought to assess immune mucosal alterations in…”
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Abstract 3059: Microbiota mediated CHI3L1 expression as a novel candidate biomarker for breast cancer progression by Mozzarelli, Alessandro Mauro, Carloni, Sara, Ferrrari, Valentina, Giugliano, Silvia, Tiraboschi, Luca, Cascio, Antonino Lo, Fornasa, Giulia, Braga, Daniele, Golzato, Davide, Segata, Nicola, Penna, Giuseppe, Rescigno, Maria

“…Abstract Over the past decade, infectious agents, including bacteria, have come under scrutiny for contributing to almost 16% of all tumors. Indeed, emerging…”
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Upholding the T cell immune-regulatory function of CD31 inhibits the formation of T/B immunological synapses in vitro and attenuates the development of experimental autoimmune arthritis in vivo by Clement, Marc, Fornasa, Giulia, Loyau, Stéphane, Morvan, Marion, Andreata, Francesco, Guedj, Kevin, Khallou-Laschet, Jamila, Larghi, Paola, Le Roux, Delphine, Bismuth, Georges, Chiocchia, Gilles, Hivroz, Claire, Newman, Debra K, Nicoletti, Antonino, Caligiuri, Giuseppina

“…Abstract CD31, a trans-homophilic inhibitory receptor expressed on both T- and B-lymphocytes, drives the mutual detachment of interacting leukocytes…”
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Sa1771 Lack of Thymic Stromal Lymphopoietin Down-Regulation on Mucosal Pro-Inflammatory Cytokines in Refractory Coeliac Disease by Biancheri, Paolo, Di Sabatino, Antonio, Fornasa, Giulia, Papadia, Cinzia, Wood, Eleanor, Forbes, Alastair, Rescigno, Maria, Corazza, Gino Roberto, MacDonald, Thomas T

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