Search Results - "Giuli, Sergio"
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Update on the challenges and recent advances in cancer immunotherapy
Published in ImmunoTargets and therapy (01-01-2013)“…This overview provides an analysis of some of the immunotherapies currently in use and under investigation, with a special focus on the tumor microenvironment,…”
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A family of Shc related proteins with conserved PTB, CH1 and SH2 regions
Published in Oncogene (01-08-1996)“…Shc proteins are targets of activated tyrosine kinases and have been implicated in the transmission of activation signals to Ras. Upon phosphorylation, Shc…”
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Shc products are substrates of erbB-2 kinase
Published in Oncogene (01-08-1993)“…The shc genes encodes three widely expressed proteins of 46, 52 and 66 kDa. Overexpression of p46shc and p52shc in NIH3T3 fibroblasts induces a tumorigenic…”
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4
Inhibition of CD4/p56lck signaling by a dominant negative mutant of the Shc adaptor protein
Published in Oncogene (16-03-1995)“…T-cell antigen receptor stimulation results in phosphorylation of the SH2 containing Shc proteins and recruitment of the Grb2/mSos complex suggesting that Shc…”
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