Search Results - "Giudice, G J"

Tight Clustering of Extracellular BP180 Epitopes Recognized by Bullous Pemphigoid Autoantibodies by Zillikens, Detlef, Rose, Pamela A., Balding, Shawn D., Liu, Zhi, Olague-Marchan, Monica, Diaz, Luis A., Giudice, George J.

“…Bullous pemphigoid is a blistering skin disease associated with autoantibodies against the BP180 antigen, a transmembrane component of the hemidesmosome…”
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The Role of Subclass Switching in the Pathogenesis of Endemic Pemphigus Foliaceus by Warren, S.J.P., Arteaga, L.A., Diaz, L.A., Rivitti, E.A., Aoki, V., Hans-Filho, G., Qaqish, B.F., Lin, M.S., Giudice, G.J.

“…Endemic pemphigus foliaceus, like the sporadic form seen in the developed world, is mediated by IgG antibodies to desmoglein-1. We studied an endemic focus in…”
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A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BP180 by ZHI LIU, DIAZ, L. A, TROY, J. L, TAYLOR, A. F, EMERY, D. J, FAIRLEY, J. A, GIUDICE, G. J

“…Subepidermal blistering associated with the human skin diseases bullous pemphigoid and herpes gestationis has been thought to be an IgG autoantibody-mediated…”
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Bullous pemphigoid and herpes gestationis autoantibodies recognize a common non-collagenous site on the BP180 ectodomain by Giudice, GJ, Emery, DJ, Zelickson, BD, Anhalt, GJ, Liu, Z, Diaz, LA

“…Bullous pemphigoid (BP) and herpes gestationis (HG) are skin diseases characterized by subepidermal blisters and autoantibodies against two hemidesmosomal Ag,…”
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BP180 gene delivery in junctional epidermolysis bullosa by SEITZ, C. S, GIUDICE, G. J, BALDING, S. D, MARINKOVICH, M. P, KHAVARI, P. A

“…Epidermolysis bullosa (EB) comprises a family of inherited blistering skin diseases for which current therapy is only palliative. Junctional EB (JEB) involves…”
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A Highly Sensitive Enzyme-Linked Immunosorbent Assay for the Detection of Circulating Anti-BP180 Autoantibodies in Patients with Bullous Pemphigoid by Zillikens, Detlef, Mascaro, Jose M., Rose, Pamela A., Liu, Zhi, Ewing, Shannon M., Caux, Frederic, Hoffmann, Raymond G., Diaz, Luis A., Giudice, George J.

“…The BP180 antigen, a component of the epidermal anchoring complex, has been identified as one of the major antigenic targets of autoantibodies associated with…”
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The Anti-Desmoglein 1 Autoantibodies in Pemphigus Vulgaris Sera are Pathogenic by Ding, Xiang, Diaz, Luis A., Fairley, Janet A., Giudice, George J., Liu, Zhi

“…Pemphigus vulgaris and pemphigus foliaceus are two closely related, but clinically and histologically distinct, autoimmune skin diseases. The autoantigens for…”
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Cloning and Primary Structural Analysis of the Bullous Pemphigoid Autoantigen BP180 by Giudice, George J, Emery, Daryl J, Diaz, Luis A

“…Bullous pemphigoid (BP) is an autoimmune skin disease that is characterized by the presence of subepidermal blisters resulting from a disruption of the…”
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Identification and Characterization of Epitopes Recognized by T Lymphocytes and Autoantibodies from Patients with Herpes Gestationis by Lin, M.-S, Gharia, M. A, Swartz, S. J, Diaz, L. A, Giudice, G. J

“…Autoantibodies associated with herpes gestationis (HG), a pregnancy-associated autoimmune skin disease, target the hemidesmosomal protein BP180. It was shown…”
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Autoantibodies in Lichen Planus Pemphigoides React with a Novel Epitope within the C-Terminal NC16A Domain of BP180 by Zillikens, Detlef, Caux, Frederic, Mascaro, Jose M., Wesselmann, Ulrich, Schmidt, Enno, Prost, Catherine, Callen, Jeffrey P., Bröcker, Eva-B, Diaz, Luis A., Giudice, George J.

“…Lichen planus pemphigoides is an autoimmune subepidermal blistering disease. The finding of immunoglobulin G antibodies directed against the basement membrane…”
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Type XVII collagen (BP180) can function as a cell−matrix adhesion molecule via binding to laminin 332 by Van den Bergh, F., Eliason, S.L., Giudice, G.J.

“…Collagen XVII (COL17) is a transmembrane glycoprotein that is expressed on the basal surface of basal epidermal keratinocytes. Previous observations have led…”
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92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen by STÅHLE-BÄCKDAHL, M, INOUE, M, GIUDICE, G. J, PARKS, W. C

“…Eosinophils are prominent in bullous pemphigoid (BP), and proteases secreted from these and other inflammatory cells may induce disruption of the basement…”
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Bullous Pemphigoid and Cicatricial Pemphigoid Autoantibodies React with Ultrastructurally Separable Epitopes on the BP180 Ectodomain: Evidence that BP180 Spans the Lamina Lucida by Bédane, Christophe, McMillan, James R., Balding, Shawn D., Bernard, Philippe, Prost, Catherine, Bonnetblanc, Jean-Marie, Diaz, Luis A., Eady, Robin A.J., Giudice, George J.

“…The BP180 antigen is a hemidesmosomal glycoprotein that is recognized by autoantibodies associated with three autoimmune disorders, bullous pemphigoid (BP),…”
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A Novel Subepidermal Blistering Disease with Autoantibodies to a 200–kDa antigen of the Basement Membrane Zone by Zillikens, Detlef, Kawahara, Yoshie, ishiko, Akira, Shimizu, Hiroshi, Mayer, Johannes, Rank, Claudia V., Liu, Zhi, Giudice, George J., Tran, Hoang H., Marinkovich, M. Peter, Bröcker, Eva-B, Hashimoto, Takashi

“…Several components of the basement membrane zone (BMZ) have been identified as antigenic targets in autoimmune bullous diseases. We report a novel disease with…”
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BP180/type XVII collagen : its role in acquired and inherited disorders or the dermal-epidermal junction by ZILLIKENS, D, GIUDICE, G. J

“…BP180 is a member of the collagen protein family and is also referred to as type XVII collagen or BP antigen 2. It is a transmembrane protein constituent of…”
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Isolation of a human epidermal cDNA corresponding to the 180-kD autoantigen recognized by bullous pemphigoid and herpes gestationis sera : immunolocalization of this protein to the hemidesmosome by DIAZ, L. A, RATRIE, H. III, SAUNDERS, W. S, FUTAMURA, S, SQUIQUERS, H. L, ANHALT, G. J, GIUDICE, G. J

“…Autoantibodies present in the sera of patients with bullous pemphigoid (BP) bind to the basement membrane zone of normal human skin and commonly recognize two…”
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Expression pattern of the bullous pemphigoid-180 antigen in normal and neoplastic epithelia by Fairley, J A, Heintz, P W, Neuburg, M, Diaz, L A, Giudice, G J

“…BP180 is a 180kDa hemidesmosomal protein recognized by bullous pemphigoid (BP) and pemphigoid gestationis (PG) autoantibodies. Recent cloning and sequence…”
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Pemphigus Foliaceus and Pemphigus Vulgaris Autoantibodies React with the Extracellular Domain of Desmoglein-1 by Emery, Daryl J., Diaz, Luis K., Fairley, Janet A., Lopez, Argelia, Taylor, Ann F., Giudice, Georg J.

“…Pemphigus foliaceus is associated with an autoimmune response against desmoglein-1; however, the fine specificity of these autoantibodies and the role that…”
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cDNA cloning of a novel human ubiquitin carrier protein. An antigenic domain specifically recognized by endemic pemphigus foliaceus autoantibodies is encoded in a secondary reading frame of this human epidermal transcript by ZHI LIU, DIAZ, L. A, HAAS, A. L, GIUDICE, G. J

“…Autoantibodies from a patient suffering from endemic pemphigus foliaceus (EPF), a blistering skin disease, were used to screen a lambda gt11 human keratinocyte…”
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A subepidermal bullous eruption associated with IgG autoantibodies to a 200 kd dermal antigen: The first case report from the United States by Mascaró, José M., Zillikens, Detlef, Giudice, George J., Caux, Fréderic, Fleming, Matthew G., Katz, Henry M., Diaz, Luis A.

“…We describe an 81-year-old white man in whom a subepidermal bullous eruption developed that clinically resembled bullous pemphigoid. The eruption promptly…”
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