Search Results - "Giuberti, Tiziana"

Characterization of Hepatitis B Virus (HBV)-Specific T-Cell Dysfunction in Chronic HBV Infection by BONI, Carolina, FISICARO, Paola, BERTOLETTI, Antonio, FERRARI, Carlo, VALDATTA, Caterina, AMADEI, Barbara, DI VINCENZO, Paola, GIUBERTI, Tiziana, LACCABUE, Diletta, ZERBINI, Alessandro, CAVALLI, Albertina, MISSALE, Gabriele

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The Characteristics of the Cell-Mediated Immune Response Identify Different Profiles of Occult Hepatitis B Virus Infection by Zerbini, Alessandro, Pilli, Massimo, Boni, Carolina, Fisicaro, Paola, Penna, Amalia, Di Vincenzo, Paola, Giuberti, Tiziana, Orlandini, Alessandra, Raffa, Giuseppina, Pollicino, Teresa, Raimondo, Giovanni, Ferrari, Carlo, Missale, Gabriele

“…Background& Aims: Hepatitis B virus (HBV) DNA detection in serum and/or in the liver of hepatitis B surface antigen (HBsAg)-negative patients with or without…”
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Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B by Fisicaro, Paola, Barili, Valeria, Montanini, Barbara, Acerbi, Greta, Ferracin, Manuela, Guerrieri, Francesca, Salerno, Debora, Boni, Carolina, Massari, Marco, Cavallo, M Cristina, Grossi, Glenda, Giuberti, Tiziana, Lampertico, Pietro, Missale, Gabriele, Levrero, Massimo, Ottonello, Simone, Ferrari, Carlo

“…Carlo Ferrari and colleagues reveal that hepatitis B virus (HBV) specific CD8 T cells from individuals with chronic HBV infections have extensive mitochondrial…”
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Restored Function of HBV-Specific T Cells After Long-term Effective Therapy With Nucleos(t)ide Analogues by Boni, Carolina, Laccabue, Diletta, Lampertico, Pietro, Giuberti, Tiziana, Viganò, Mauro, Schivazappa, Simona, Alfieri, Arianna, Pesci, Marco, Gaeta, Giovanni B, Brancaccio, Giuseppina, Colombo, Massimo, Missale, Gabriele, Ferrari, Carlo

“…Background & Aims In patients with chronic hepatitis B virus (HBV) infection, persistent exposure to high concentrations of antigen can disrupt T-cell…”
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TLR7 Agonist Increases Responses of Hepatitis B Virus–Specific T Cells and Natural Killer Cells in Patients With Chronic Hepatitis B Treated With Nucleos(T)Ide Analogues by Boni, Carolina, Vecchi, Andrea, Rossi, Marzia, Laccabue, Diletta, Giuberti, Tiziana, Alfieri, Arianna, Lampertico, Pietro, Grossi, Glenda, Facchetti, Floriana, Brunetto, Maurizia R., Coco, Barbara, Cavallone, Daniela, Mangia, Alessandra, Santoro, Rosanna, Piazzolla, Valeria, Lau, Audrey, Gaggar, Anuj, Subramanian, G. Mani, Ferrari, Carlo

“…The oral Toll-like receptor (TLR) 7 agonist GS-9620 has antiviral effects in woodchuck and chimpanzee models of chronic hepatitis B virus (HBV) infection. We…”
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Combined Blockade of Programmed Death-1 and Activation of CD137 Increase Responses of Human Liver T Cells Against HBV, But Not HCV by Fisicaro, Paola, Valdatta, Caterina, Massari, Marco, Loggi, Elisabetta, Ravanetti, Lara, Urbani, Simona, Giuberti, Tiziana, Cavalli, Albertina, Vandelli, Carmen, Andreone, Pietro, Missale, Gabriele, Ferrari, Carlo

“…Background & Aims In patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, antiviral functions of T cells are impaired; these…”
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Natural killer cell phenotype modulation and natural killer/T‐cell interplay in nucleos(t)ide analogue‐treated hepatitis e antigen‐negative patients with chronic hepatitis B by Boni, Carolina, Lampertico, Pietro, Talamona, Lavinia, Giuberti, Tiziana, Invernizzi, Federica, Barili, Valeria, Fisicaro, Paola, Rossi, Marzia, Cavallo, Maria Cristina, Vecchi, Andrea, Pedrazzi, Giuseppe, Alfieri, Arianna, Colombo, Massimo, Missale, Gabriele, Ferrari, Carlo

“…Natural killer (NK) and hepatitis B virus (HBV)‐specific T cells are functionally impaired in chronic hepatitis B (CHB). Understanding to what extent…”
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Peginterferon-α does not improve early peripheral blood HBV-specific T-cell responses in HBeAg-negative chronic hepatitis by Penna, Amalia, Laccabue, Diletta, Libri, Irene, Giuberti, Tiziana, Schivazappa, Simona, Alfieri, Arianna, Mori, Cristina, Canetti, Diana, Lampertico, Pietro, Viganò, Mauro, Colombo, Massimo, Loggi, Elisabetta, Missale, Gabriele, Ferrari, Carlo

“…Background & Aims The effect of IFN-α therapy on HBV-specific T-cell responses in HBeAg-negative, genotype D, chronic hepatitis B is largely undefined…”
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Randomised study comparing 48 and 96 weeks peginterferon α-2a therapy in genotype D HBeAg-negative chronic hepatitis B by Lampertico, Pietro, Viganò, Mauro, Di Costanzo, Giovan Giuseppe, Sagnelli, Evangelista, Fasano, Massimo, Di Marco, Vito, Boninsegna, Sara, Farci, Patrizia, Fargion, Silvia, Giuberti, Tiziana, Iannacone, Claudio, Regep, Loredana, Massetto, Benedetta, Facchetti, Floriana, Colombo, Massimo

“…Treatment with peginterferon α-2a (PegIFN) for 48 weeks is the standard of care for selected HBeAg-negative patients chronically infected with hepatitis B…”
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What to start with in first line treatment of chronic hepatitis B patients: an Italian multicentre observational cohort, HBV-RER study group by Cuomo, Gianluca, Borghi, Vanni, Giuberti, Tiziana, Andreone, Pietro, Massari, Marco, Villa, Erica, Pietrangelo, Antonello, Verucchi, Gabriella, Levantesi, Fabio, Ferrari, Carlo

“…Treatment options for chronic hepatitis B (CHB) are pegylated interferon (Peg-IFN) in minimal-mild liver fibrosis and nucleot(s)ide analogues (NUC) in more…”
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Evolving clinical landscape of chronic hepatitis B: A multicenter Italian study by Stroffolini, Tommaso, Almasio, Piero L, Sagnelli, Evangelista, Mele, Alfonso, Gaeta, Giovanni Battista

“…The aim of the study was to evaluate the characteristics of chronic hepatitis B with special reference to the geographical origin of the patients and to the…”
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Oral lichen planus pathogenesis: A role for the HCV-specific cellular immune response by Pilli, Massimo, Penna, Amalia, Zerbini, Alessandro, Vescovi, Paolo, Manfredi, Maddalena, Negro, Francesco, Carrozzo, Marco, Mori, Cristina, Giuberti, Tiziana, Ferrari, Carlo, Missale, Gabriele

“…Hepatitis C virus infection can be associated with different extrahepatic manifestations, including lichen planus; however, no clear role for HCV in their…”
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Treatment of chronic hepatitis B: Recommendations from an Italian workshop by Carosi, G, Rizzetto, M

“…Abstract The changing scenario of hepatitis B virus therapy has encouraged the organisation of a workshop, endorsed by three Italian scientific societies,…”
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Multiple changes in thyroid function in patients with chronic active HCV hepatitis treated with recombinant interferon-alpha by Roti, E, Minelli, R, Giuberti, T, Marchelli, S, Schianchi, C, Gardini, E, Salvi, M, Fiaccadori, F, Ugolotti, G, Neri, T M, Braverman, L E

“…Recombinant human interferon-alpha (r-IFN-alpha) is often successfully used in the treatment of patients with chronic viral hepatitis B and C. Thyroid…”
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Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen by Penna, A, Chisari, F V, Bertoletti, A, Missale, G, Fowler, P, Giuberti, T, Fiaccadori, F, Ferrari, C

“…The absence of readily manipulable experimental systems to study the cytotoxic T lymphocyte (CTL) response against hepatitis B virus (HBV) antigens has thus…”
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T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections by Ferrari, C, Valli, A, Galati, L, Penna, A, Scaccaglia, P, Giuberti, T, Schianchi, C, Missale, G, Marin, M G, Fiaccadori, F

“…Twenty-nine patients with chronic hepatitis C and 15 asymptomatic hepatitis C virus antibody-positive subjects who clinically recovered from hepatitis C virus…”
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Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope by BERTOLETTI, A, COSTANZO, A, CHISARI, F. V, LEVRERO, M, ARTINI, M, SETTE, A, PENNA, A, GIUBERTI, T, FIACCADORI, F, FERRARI, C

“…Mutations that abrogate recognition of a viral epitope by class I-restricted cytotoxic T lymphocyte (CTL) can lead to viral escape if the CTL response against…”
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Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection by Ferrari, C, Penna, A, Bertoletti, A, Valli, A, Antoni, AD, Giuberti, T, Cavalli, A, Petit, MA, Fiaccadori, F

“…The proliferative response of PBMC to hepatitis B virus (HBV) envelope, core, and e Ag was analyzed prospectively in 21 patients with acute self-limited HBV…”
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Oral lichen planus pathogenesis: A role for the HCV‐specific cellular immune response by Pilli, Massimo, Penna, Amalia, Zerbini, Alessandro, Vescovi, Paolo, Manfredi, Maddalena, Negro, Francesco, Carrozzo, Marco, Mori, Cristina, Giuberti, Tiziana, Ferrari, Carlo, Missale, Gabriele

“…Hepatitis C virus infection can be associated with different extrahepatic manifestations, including lichen planus; however, no clear role for HCV in their…”
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Effects of excess iodine administration on thyroid function in euthyroid patients with a previous episode of thyroid dysfunction induced by interferon-alpha treatment by Minelli, Roberta, Braverman, Lewis E., Giuberti, Tiziana, Schianchi, Claudia, Gardini, Eliana, Salvi, Mario, Fiaccadori, Franco, Ugolotti, Giorgio, Roti, Elio

“…OBJECTIVE To determine the effects of pharmacological quantities of iodide (SSKI) on thyroid function in euthyroid patients previously treated with recombinant…”
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