Search Results - "Gitter, B."

Haspin inhibition delays cell cycle progression through interphase in cancer cells by Wang, Peiling, Hua, Xiangmei, Bryner, Yuge Han, Liu, Sijing, Gitter, Christopher B., Dai, Jun

“…Haspin (Haploid Germ Cell‐Specific Nuclear Protein Kinase) is a serine/threonine kinase pertinent to normal mitosis progression and mitotic phosphorylation of…”
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Calcium phosphate nanoparticles as efficient carriers for photodynamic therapy against cells and bacteria by Schwiertz, J, Wiehe, A, Gräfe, S, Gitter, B, Epple, M

“…Abstract Calcium phosphate nanoparticles were surface-functionalized with different polymers, and photosensitizers were incorporated into this layer. The…”
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Antimicrobial photodynamic active biomaterials for periodontal regeneration by Sigusch, B.W., Dietsch, S., Berg, A., Voelpel, A., Guellmar, A., Rabe, U., Schnabelrauch, M., Steen, D., Gitter, B., Albrecht, V., Watts, D.C., Kranz, S.

“…Biomaterials for periodontal regeneration may have insufficient mechanical and antimicrobial properties or are difficult to apply under clinical conditions…”
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Positively charged calcium phosphate/polymer nanoparticles for photodynamic therapy by Klesing, J., Wiehe, A., Gitter, B., Gräfe, S., Epple, M.

“…The charge of nanoparticles influences their ability to pass through the cellular membrane, and a positive charge should be beneficial. The negative charge of…”
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Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain by Dovey, H. F., John, V., Anderson, J. P., Chen, L. Z., De Saint Andrieu, P., Fang, L. Y., Freedman, S. B., Folmer, B., Goldbach, E., Holsztynska, E. J., Hu, K. L., Johnson‐Wood, K. L., Kennedy, S. L., Kholodenko, D., Knops, J. E., Latimer, L. H., Lee, M., Liao, Z., Lieberburg, I. M., Motter, R. N., Mutter, L. C., Nietz, J., Quinn, K. P., Sacchi, K. L., Seubert, P. A., Shopp, G. M., Thorsett, E. D., Tung, J. S., Wu, J., Yang, S., Yin, C. T., Schenk, D. B., May, P. C., Altstiel, L. D., Bender, M. H., Boggs, L. N., Britton, T. C., Clemens, J. C., Czilli, D. L., Dieckman‐McGinty, D. K., Droste, J. J., Fuson, K. S., Gitter, B. D., Hyslop, P. A., Johnstone, E. M., Li, W‐Y., Little, S. P., Mabry, T. E., Miller, F. D., Ni, B., Nissen, J. S., Porter, W. J., Potts, B. D., Reel, J. K., Stephenson, D., Su, Y., Shipley, L. A., Whitesitt, C. A., Yin, T., Audia, J. E.

“…Converging lines of evidence implicate the beta‐amyloid peptide (Aβ) as causative in Alzheimer's disease. We describe a novel class of compounds that reduce Aβ…”
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Induction of apoptosis in HaCaT cells by photodynamic therapy with chlorin e6 or pheophorbide a by Radestock, A, Elsner, P, Gitter, B, Hipler, U-C

“…The two photosensitizers, chlorin e6 and pheophorbide a, were tested in an in vitro model of topical photodynamic therapy (PDT). Both dyes accumulate in HaCaT…”
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Amyloid β Peptide Potentiates Cytokine Secretion by Interleukin-1 β-Activated Human Astrocytoma Cells by Gitter, Bruce D., Cox, Laura M., Rydel, Russell E., May, Patrick C.

“…Neurodegenerative processes in Alzheimer disease (AD) are thought to be driven in part by the deposition of amyloid β (Aβ), a 39- to 43-amino acid peptide…”
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Reliability and longevity of implantable defibrillators by Hauser, Robert G., Casey, Susan A., Gitter, Christopher B., Tang, Chuen Y., Abdelhadi, Raed H., Gornick, Charles C., Stanberry, Larissa, Sengupta, Jay D.

“…Purpose We hypothesized that data in manufacturers’ product performance reports (PPRs) can provide clinically valuable ICD and cardiac resynchronization…”
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Study of the analgesic effect of lanepitant in patients with osteoarthritis pain by Goldstein, David J., Wang, Ouhong, Todd, Lora E., Gitter, Bruce D., DeBrota, David J., Iyengar, Smriti

“…Objective Lanepitant selectively blocks substance P binding to the neurokinin‐1 receptor, preventing neurogenic inflammation and pain transmission. Substance P…”
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Improved Photoinactivation of Gram-Negative and Gram-Positive Methicillin-Resistant Bacterial Strains Using a New Near-Infrared Absorbing Meso-Tetrahydroporphyrin : A Comparative Study with a Chlorine e6 Photosensitizer Photolon by SCHASTAK, S, GITTER, B, HANDZEL, R, HERMANN, R, WIEDEMANN, P

“…The antimicrobial activity of new tetracationic and water-soluble meso-substituted tetrahydroporphyrin tetratosylat (BL1065) and of dicationic water-soluble…”
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Evidence supporting a role for anti-Aβ antibodies in the treatment of Alzheimer’s disease by Morgan, Dave, Gitter, Bruce D

“…Antibodies against Aβ have been suggested as potential therapeutic strategies for the treatment of Alzheimer disease (AD) for nearly 8 years. Animal studies…”
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Pharmacological characterization of LY303870: a novel, potent and selective nonpeptide substance P (neurokinin-1) receptor antagonist by Gitter, B D, Bruns, R F, Howbert, J J, Waters, D C, Threlkeld, P G, Cox, L M, Nixon, J A, Lobb, K L, Mason, N R, Stengel, P W

“…LY303870 [(R)-1-[N-(2-methoxybenzyl)acetylamino]-3-(1H-indol-3-yl)-2-[N-(2-(4- (piperidin-1-yl)piperidin-1-yl)acetyl)amino]propane] is a new, potent and…”
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Interleukin-6 secretion from human astrocytoma cells induced by substance P by Gitter, B D, Regoli, D, Howbert, J J, Glasebrook, A L, Waters, D C

“…Functional NK-1 (substance P) receptors have been demonstrated previously on astrocytes from primary newborn rat brain cultures and human astrocytoma cells…”
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Species differences in affinities of non-peptide antagonists for substance P receptors by Gitter, B D, Waters, D C, Bruns, R F, Mason, N R, Nixon, J A, Howbert, J J

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Regulation of Cytokine Secretion and Amyloid Precursor Protein Processing by Proinflammatory Amyloid Beta (Aβ) by GITTER, BRUCE D., BOGGS, LEONARD N., MAY, PATRICK C., CZILLI, DAN L., CARLSON, CHRISTOPHER D.

“…: Neurodegenerative processes in Alzheimer's disease (AD) are thought to be driven, in part, by the deposition of amyloid beta (Aβ), a 39‐43‐aminoacid peptide…”
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Influence of stringent and relaxed response on excretion of recombinant proteins and fatty acid composition in Escherichia coli by GITTER, B, DIEFENBACH, R, KEWELOH, H, RIESENBERG, D

“…In contrast to stringent (relA+) cells of Escherichia coli, relaxed (relA) cells excreted recombinant proteins (beta-lactamase, interferon alpha 1) into the…”
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Characteristics of human synovial fibroblast activation by IL-1β and TNFα by GITTER, B. D, LABUS, J. M, LEES, S. L, SCHEETZ, M. E

“…Human synovial fibroblast cell lines (HSN), established from tissues obtained from the knee joints of arthritis patients undergoing arthoplasty, were used to…”
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[3H]LY303870, a novel nonpeptide radioligand for the NK-1 receptor by Gehlert, D R, Schober, D A, Hipskind, P A, Gitter, B D, Howbert, J J

“…We synthesized a potent and selective antagonist radioligand for the neurokinin (NK)-1 receptor and characterized its binding to guinea pig striatal membranes…”
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Dose-response study of the analgesic effect of Lanepitant in patients with painful diabetic neuropathy by GOLDSTEIN, David J, OUHONG WANG, GITTER, Bruce D, IYENGAR, Smriti

“…Lanepitant is effective in the formalin analgesic model suggesting efficacy in painful neuropathy. This study was designed to evaluate the dose-response effect…”
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Use of non-peptide tachykinin receptor antagonists to substantiate the involvement of NK1 and NK2 receptors in a spinal nociceptive reflex in the rat by Picard, P, Boucher, S, Regoli, D, Gitter, B D, Howbert, J J, Couture, R

“…Non-peptide antagonists of the NK1 and NK2 receptors were tested as inhibitors of the reaction time in the rat tail-flick and on the decrease of reaction time…”
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