Search Results - "Gittenberger‐de Groot, AC"

Maternal hyperhomocysteinaemia is a risk factor for congenital heart disease by Verkleij‐Hagoort, AC, Verlinde, M, Ursem, NTC, Lindemans, J, Helbing, WA, Ottenkamp, J, Siebel, FMH, Gittenberger‐de Groot, AC, De Jonge, R, Bartelings, MM, Steegers, EAP, Steegers‐Theunissen, RPM

“…Objective  To investigate the inter‐relation between mother and infant homocysteine, folate and vitamin B12 status and the risk of a child with congenital…”
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Basics of cardiac development for the understanding of congenital heart malformations by GITTENBERGER-DE GROOT, Adriana C, BARTELINGS, Margot M, DERUITER, Marco C, POELMANN, Robert E

“…Cardiovascular development has become a crucial element of transgene technology in that many transgenic and knockout mice unexpectedly present with a cardiac…”
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PDGF‐B signaling is important for murine cardiac development: Its role in developing atrioventricular valves, coronaries, and cardiac innervation by Van den Akker, Nynke M.S., Winkel, Leah C.J., Nisancioglu, Maya H., Maas, Saskia, Wisse, Lambertus J., Armulik, Annika, Poelmann, Robert E., Lie‐Venema, Heleen, Betsholtz, Christer, Gittenberger‐de Groot, Adriana C.

“…We hypothesized that PDGF‐B/PDGFR‐β‐signaling is important in the cardiac contribution of epicardium‐derived cells and cardiac neural crest, cell lineages…”
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Histological evaluation of decellularised porcine aortic valves: matrix changes due to different decellularisation methods by Grauss, Robert W., Hazekamp, Mark G., Oppenhuizen, Ferdinand, van Munsteren, Conny J., Gittenberger-de Groot, Adriana C., DeRuiter, Marco C.

“…Objective: Several decellularisation techniques have been developed to produce acellular matrix scaffolds for the purpose of tissue engineering, mostly…”
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Temporal and Distinct TGFβ Ligand Requirements during Mouse and Avian Endocardial Cushion Morphogenesis by Camenisch, Todd D., Molin, Daniël G.M., Person, Anthony, Runyan, Raymond B., Gittenberger-de Groot, Adriana C., McDonald, John A., Klewer, Scott E.

“…The formation of endocardial cushions in the atrioventricular (AV) canal of the rudimentary heart requires epithelial-to-mesenchymal cell transformation (EMT)…”
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Changes in Shear Stress–Related Gene Expression After Experimentally Altered Venous Return in the Chicken Embryo by Groenendijk, Bianca C.W, Hierck, Beerend P, Vrolijk, Johannes, Baiker, Martin, Pourquie, Mathieu J.B.M, Gittenberger-de Groot, Adriana C, Poelmann, Robert E

“…Hemodynamics play an important role in cardiovascular development, and changes in blood flow can cause congenital heart malformations. The endothelium and…”
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Preservation of left ventricular function and attenuation of remodeling after transplantation of human epicardium-derived cells into the infarcted mouse heart by WINTER, E. M, GRAUSS, R. W, STEENDIJK, P, DOEVENDANS, P. A, VAN DER LAARSE, A, POELMANN, R. E, SCHALIJ, M. J, ATSMA, D. E, GITTENBERGER-DE GROOT, A. C, HOGERS, B, VAN TUYN, J, VAN DER GEEST, R, LIE-VENEMA, H, VICENTE STEIJN, R, MAAS, S, DERUITER, M. C, DEVRIES, A. A. F

“…Proper development of compact myocardium, coronary vessels, and Purkinje fibers depends on the presence of epicardium-derived cells (EPDCs) in embryonic…”
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Differential and linear insertion of atrioventricular valves: a useful tool? by Adriaanse, B. M. E., Bartelings, M. M., van Vugt, J. M. G., Chaoui, R., Gittenberger‐de Groot, A. C., Haak, M. C.

“…ABSTRACT Objective The differential insertion of the atrioventricular valves is the ultrasonographic representation of the more apical attachment of the…”
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Double-outlet right ventricle and overriding tricuspid valve reflect disturbances of looping, myocardialization, endocardial cushion differentiation, and apoptosis in TGF-beta(2)-knockout mice by Bartram, U, Molin, D G, Wisse, L J, Mohamad, A, Sanford, L P, Doetschman, T, Speer, C P, Poelmann, R E, Gittenberger-de Groot, A C

“…Transforming growth factor-beta(2) (TGF-beta(2)) is a member of a family of growth factors with the potential to modify multiple processes. Mice deficient in…”
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Transforming growth factor beta in cardiovascular development and function by Azhar, Mohamad, Schultz, Jo El J., Grupp, Ingrid, Dorn, Gerald W., Meneton, Pierre, Molin, Daniel G.M., Gittenberger-de Groot, Adriana C., Doetschman, Thomas

“…Transforming growth factor betas (TGFβs) are pleiotropic cytokines involved in many biological processes. Genetic engineering and tissue explanation studies…”
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Monocilia on chicken embryonic endocardium in low shear stress areas by Van der Heiden, Kim, Groenendijk, Bianca C.W., Hierck, Beerend P., Hogers, Bianca, Koerten, Henk K., Mommaas, A. Mieke, Gittenberger‐de Groot, Adriana C., Poelmann, Robert E.

“…During cardiovascular development, fluid shear stress patterns change dramatically due to extensive remodeling. This biomechanical force has been shown to…”
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VEGF : A modifier of the del22q11 (DiGeorge) syndrome? by Conway, Simon J, Carmeliet, Peter, Stalmans, Ingeborg, Lambrechts, Diether, De smet, Frederik, Jansen, Sandra, Wang, Jian, Maity, Sunit, Kneer, Paige, von der Ohe, Maren, Swillen, Ann, Maes, Christa, Gewillig, Marc, Molin, Daniel G.M, Hellings, Peter, Boetel, Thurid, Haardt, Maartin, Compernolle, Veerle, Dewerchin, Mieke, Plaisance, Stephane, Vlietinck, Robert, Emanuel, Beverly, Gittenberger-de Groot, Adriana C, Scambler, Peter, Morrow, Bernice, Driscol, Deborah A, Moons, Lieve, Esguerra, Camila V, Carmeliet, Geert, Behn-Krappa, Annett, Devriendt, Koen, Collen, Désiré

“…Hemizygous deletion of chromosome 22q11 (del22q11) causes thymic, parathyroid, craniofacial and life-threatening cardiovascular birth defects in 1 in 4,000…”
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Development‐related changes in the expression of shear stress responsive genes KLF‐2, ET‐1, and NOS‐3 in the developing cardiovascular system of chicken embryos by Groenendijk, Bianca C.W., Hierck, Beerend P., Gittenberger‐de Groot, Adriana C., Poelmann, Robert E.

“…Blood flow patterns play an important role in cardiovascular development, as changes can cause congenital heart malformations. Shear stress is positively…”
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Histology of Vascular Myocardial Wall of Left Atrial Body After Pulmonary Venous Incorporation by Douglas, Yvonne L., Jongbloed, Monique R.M., Gittenberger-de Groot, Adriana C., Evers, Dorothea, Dion, Robert A.E., Voigt, Pieter, Bartelings, Margot M., Schalij, Martin J., Ebels, Tjark, DeRuiter, Marco C.

“…During embryonic development, the common pulmonary vein (PV) becomes incorporated into the left atrium, giving rise to separate PV ostia. We describe the…”
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Epicardium-Derived Cells Contribute a Novel Population to the Myocardial Wall and the Atrioventricular Cushions by Gittenberger-de Groot, Adriana C, Vrancken Peeters, Mark-Paul F.M, Mentink, Monica M.T, Gourdie, Robert G, Poelmann, Robert E

“…The epicardium and dorsal mesocardium are known to be the source of structures that form the wall of the coronary vessels. Because mouse knockout studies have…”
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Embryonic conduction tissue: a spatial correlation with adult arrhythmogenic areas by Jongbloed, Monique R M, Schalij, Martin J, Poelmann, Robert E, Blom, Nico A, Fekkes, Madelon L, Wang, Zhiyong, Fishman, Glenn I, Gittenberger-De Groot, Adriana C

“…The occurrence of arrhythmias in adult patients may arise preferentially in anatomic regions derived from the specialized cardiac conduction system. To examine…”
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Decellularization of rat aortic valve allografts reduces leaflet destruction and extracellular matrix remodeling by Grauss, R.W, Hazekamp, M.G, van Vliet, S, Gittenberger-de Groot, A.C, DeRuiter, M.C

“…Decellularization of aortic valve allografts in advance of transplantation is a promising approach to overcome immune-induced early graft failure. In this…”
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Coronary Artery and Orifice Development Is Associated With Proper Timing of Epicardial Outgrowth and Correlated Fas Ligand Associated Apoptosis Patterns by Eralp, Ismail, Lie-Venema, Heleen, DeRuiter, Marco C, van den Akker, Nynke M.S, Bogers, Ad J.J.C, Mentink, Monica M.T, Poelmann, Robert E, Gittenberger-de Groot, Adriana C

“…The proepicardial organ provides differentiated cell types to the myocardial wall and facilitates coronary development. Ingrowth of the coronary arteries into…”
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Smooth Muscle Cell Origin and Its Relation to Heterogeneity in Development and Disease by Gittenberger-de Groot, Adriana C, DeRuiter, Marco C, Bergwerff, Maarten, Poelmann, Robert E

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Epicardial Outgrowth Inhibition Leads to Compensatory Mesothelial Outflow Tract Collar and Abnormal Cardiac Septation and Coronary Formation by Gittenberger-de Groot, Adriana C, Vrancken Peeters, Mark-Paul F.M, Bergwerff, Maarten, Mentink, Monica M.T, Poelmann, Robert E

“…In the present study, we investigated the modulatory role of the epicardium in myocardial and coronary development. Epicardial cell tracing experiments have…”
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