Search Results - "Githanga, Jessie"

Risk factors for abandonment of Wilms tumor therapy in Kenya by Libes, Jaime, Oruko, Oliver, Abdallah, Fatmah, Githanga, Jessie, Ndung'u, James, Musimbi, Joyce, Njuguna, Festus, Patel, Kirtika, White, John, Axt, Jason R., O'Neill Jr, James A., Shrubsole, Martha, Li, Ming, Lovvorn III, Harold N.

“…Background Survival from Wilms tumor (WT) in sub‐Saharan Africa remains dismal as a result of on‐therapy mortality and treatment abandonment. Review of…”
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NRF2/ACSS2 axis mediates the metabolic effect of alcohol drinking on esophageal squamous cell carcinoma by Odera, Joab Otieno, Xiong, Zhaohui, Huang, Caizhi, Gu, Ning, Yang, Wenjun, Githang'a, Jessie, Odera, Elizabeth, Paiboonrungruang, Chorlada, Chen, Xiaoxin

“…Alcohol drinking is a leading risk factor for the development of esophageal squamous cell carcinoma (ESCC). However, the molecular mechanisms of…”
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The cost‐effectiveness of treating childhood cancer in 4 centers across sub‐Saharan Africa by Githang’a, Jessie, Brown, Biobele, Chitsike, Inam, Schroeder, Kristin, Chekwenda‐Makore, Nester, Majahasi, Flora, Ogundoyin, Olakayode, Renner, Lorna, Petricca, Kadia, Denburg, Avram E., Horton, Sue E., Gupta, Sumit

“…Background The treatment of childhood cancer often is assumed to be costly in African settings, thereby limiting advocacy and policy efforts. The authors…”
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Barriers to effective childhood cancer control in Kenya (BECK) study, 2019-2020: A mixed methods study in a national tertiary facility and 10 regional cancer treatment centers by Mwenda, Valerian, Karagu, Alfred, Githanga, Jessie Nyokabi, Nyangasi, Mary

“…10018 Background: Globally, 80,000 children die from cancer annually; 80% in low- and middle-income countries (LMICs). Childhood cancer cure is possible in…”
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Ticagrelor vs placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: the HESTIA3 study by Heeney, Matthew M., Abboud, Miguel R., Githanga, Jessie, Inusa, Baba P.D., Kanter, Julie, Michelson, Alan D., Nduba, Videlis, Musiime, Victor, Apte, Mohini, Inati, Adlette, Taksande, Amar M., Andersson, Marielle, Åstrand, Magnus, Maklad, Noha, Niazi, Mohammad, Himmelmann, Anders, Berggren, Anders R.

“…The phase 3 HESTIA3 study assessed the efficacy and safety of the reversible P2Y12 inhibitor ticagrelor vs placebo in preventing vaso-occlusive crises in…”
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Transcranial Doppler Screening of Children with Sickle Cell Disease for a Large, Multinational Interventional Study: Experience from the Phase 3 HOPE-Kids 2 Trial Investigating the Effect of Voxelotor Treatment on Transcranial Doppler Flow Velocity by Bello-Manga, Halima, Nduba, Videlis, Abdullahi, Shehu Umar, Githanga, Jessie, Ogutu, Bernhards, El-Beshlawy, Amal M., Hassab, Hoda MA, Badr, Mohamed, Tantawy, Azza, Brown, Biobele J, Paintsil, Vivian, Akinsete, Adeseye Michael, Segbefia, Catherine I., Okpala, Iheanyi, Wali, Yasser, Essa, Mohammed, Farthing, Jason, Doss, Jennifer, Dixon, Sandy, Brown, Clark, Kirkham, Fenella

“…Introduction: Transcranial Doppler (TCD) ultrasound is an effective screening tool for identifying children with sickle cell disease (SCD) who are at high risk…”
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Haematopathology diagnosis: Role of multidisciplinary training workshops by Githang’a, Jessie, Hurwitz, Nina

“…No related abstract found…”
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Task Sharing and Shifting to Provide Pathology Diagnostic Services: The Kenya Fine-Needle Aspiration Biopsy Cytology and Bone Marrow Aspiration and Trephine Biopsy Training Program by Sayed, Shahin, Field, Andrew, Rajab, Jamilla, Mutuiri, Anderson, Githanga, Jessie, Mungania, Mary, Okinda, Nancy, Moloo, Zahir, Abdillah, Abubakar, Ayara, Brian, Chesori, Erick, Muthua, Julia, Obosy, Leah, Massawa, Thaddeus, Obiero, Okoth, Kagotho, Elizabeth, Shikuku, Peter K, Gachii, Andrew K, Migide, Eunida, Muninzwa, Donstefano, Dawsey, Sanford M, Muchiri, Lucy

“…Fine-needle aspiration biopsy (FNAB) cytology is a simple, inexpensive, and accurate diagnostic test for benign, infectious, and malignant lesions of the…”
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Pharmacokinetics and safety of ticagrelor in infants and toddlers with sickle cell disease aged <24 months by Duniva Inusa, Baba Psalm, Inati, Adlette, Maes, Philip, Githanga, Jessie, Ogutu, Bernhards, Abboud, Miguel R., Miano, Maurizio, Cela, Elena, Nduba, Videlis, Niazi, Mohammad, Åstrand, Magnus, Persson, Kevin, Berggren, Anders, Carlson, Glenn

“…Inhibition of platelet activation may reduce vaso‐occlusion rates in patients with sickle cell disease (SCD). In the HESTIA4 (NCT03492931) study, 21 children…”
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Pharmacokinetics of Ticagrelor in Infants and Toddlers Aged <24 Months with Sickle Cell Disease by Inusa, Baba PD, Inati, Adlette, Maes, Philip, Githanga, Jessie, Abboud, Miguel R., Miano, Maurizio, Cela, Elena, Nduba, Videlis, Niazi, Mohammad, Åstrand, Magnus, Persson, Kevin, Berggren, Anders Rikard, Carlson, Glenn

“…Background: There is a significant unmet need for treatments to reduce vaso-occlusive crises (VOCs) in sickle cell disease (SCD). Until recently, the only…”
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Esophageal Squamous Dysplasia is Common in Asymptomatic Kenyans: A Prospective, Community-Based, Cross-Sectional Study by Mwachiro, Michael M, Burgert, Stephen L, Lando, Justus, Chepkwony, Robert, Bett, Collins, Bosire, Claire, Abnet, Christian C, Githanga, Jessie, Waweru, Wairimu, Giffen, Carol A, Murphy, Gwen, White, Russell E, Topazian, Mark D, Dawsey, Sanford M

“…Esophageal squamous cell carcinoma (ESCC) is endemic in east Africa and is a leading cause of cancer death among Kenyans. The asymptomatic precursor lesion of…”
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Prevalence of esophageal squamous dysplasia in relatives of patients with esophageal cancer in Southwestern Kenya by Lando, Justus O., Mwachiro, Michael M., Parker, Robert K., Albert, Paul S., White, Russell E., Burgert, Stephen L., Chepkwony, Robert, Abnet, Christian C., Githanga, Jessie, Topazian, Mark D., Dawsey, Sanford M.

“…Esophageal squamous cell carcinoma (ESCC) and its asymptomatic precursor lesion, esophageal squamous dysplasia (ESD), are common in East Africa. It is unknown…”
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The management of children with Kaposi sarcoma in resource limited settings by Molyneux, Elizabeth, Davidson, Alan, Orem, Jackson, Hesseling, Peter, Balagadde-Kambugu, Joyce, Githanga, Jessie, Israels, Trijn

“…Kaposi sarcoma (KS) is common where HIV infection is endemic. Antiretroviral therapy (ART) has reduced the incidence in well‐resourced settings but in some…”
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Lymphomas in sub‐Saharan Africa – what can we learn and how can we help in improving diagnosis, managing patients and fostering translational research? by Naresh, Kikkeri N., Raphael, Martine, Ayers, Leona, Hurwitz, Nina, Calbi, Valeria, Rogena, Emily, Sayed, Shahin, Sherman, Omar, Ibrahim, Hazem A.H., Lazzi, Stefano, Mourmouras, Vasileios, Rince, Patricia, Githanga, Jessie, Byakika, Bessie, Moshi, Emma, Durosinmi, Muheez, Olasode, Babatunde J., Oluwasola, Olayiwola A., Akang, Effiong E., Akenòva, Yetunde, Adde, Melissa, Magrath, Ian, Leoncini, Lorenzo

“…Summary Approximately 30 000 cases of non‐Hodgkin lymphoma (NHL) occur in the equatorial belt of Africa each year. Apart from the fact that Burkitt lymphoma…”
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Ticagrelor versus placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: Rationale and design of a randomized, double-blind, parallel-group, multicenter phase 3 study (HESTIA3) by Heeney, Matthew M., Abboud, Miguel R., Amilon, Carl, Andersson, Marielle, Githanga, Jessie, Inusa, Baba, Kanter, Julie, Leonsson-Zachrisson, Maria, Michelson, Alan D., Berggren, Anders R.

“…An unmet need for therapies exists to reduce sickle cell disease (SCD) complications in pediatric patients. Activated platelets contribute to the formation of…”
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Genetic and chromosomal alterations in Kenyan Wilms Tumor by Lovvorn III, Harold N., Pierce, Janene, Libes, Jaime, Li, Bingshan, Wei, Qiang, Correa, Hernan, Gouffon, Julia, Clark, Peter E., Axt, Jason R., Hansen, Erik, Newton, Mark, O'Neill Jr, James A.

“…Wilms tumor (WT) is the most common childhood kidney cancer worldwide and poses a cancer health disparity to black children of sub‐Saharan African ancestry…”
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Wilms tumor survival in Kenya by Axt, Jason, Abdallah, Fatmah, Axt, Meridith, Githanga, Jessie, Hansen, Erik, Lessan, Joel, Li, Ming, Musimbi, Joyce, Mwachiro, Michael, Newton, Mark, Ndung’u, James, Njuguna, Festis, Nzioka, Ancent, Oruko, Oliver, Patel, Kirtika, Tenge, Robert, Ukoli, Flora, White, Russel, O’Neill, James A, Lovvorn, Harold N

“…Abstract Purpose Survival from Wilms Tumor (WT) exceeds 90% at 5 years in developed nations, whereas at last report, 2-year event-free survival (EFS) in Kenya…”
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Digital cancer pathology in Africa by Dimaras, Helen, Dimba, Elizabeth AO, Waweru, Wairimu, Githanga, Jessie, Kimani, Kahaki

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Achieving optimal cancer outcomes in East Africa through multidisciplinary partnership: a case study of the Kenyan National Retinoblastoma Strategy group by Hill, Jessica A, Kimani, Kahaki, White, Abby, Barasa, Faith, Livingstone, Morgan, Gallie, Brenda L, Dimaras, Helen

“…Strategic, interdisciplinary partnerships are essential to addressing the complex drivers of health inequities that result in survival disparities worldwide…”
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Design and Implementation of the Retinoblastoma Collaborative Laboratory by Qaiser, Seemi, Limo, Alice, Gichana, Josiah, Kimani, Kahaki, Githanga, Jessie, Waweru, Wairimu, Dimba, Elizabeth A.O., Dimaras, Helen

“…Purpose: The purpose of this work was to describe the design and implementation of a digital pathology laboratory, the Retinoblastoma Collaborative Laboratory…”
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