Search Results - "Gisslèn, M."

Week 96 efficacy and safety results of the phase 3, randomized EMERALD trial to evaluate switching from boosted-protease inhibitors plus emtricitabine/tenofovir disoproxil fumarate regimens to the once daily, single-tablet regimen of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) in treatment-experienced, virologically-suppressed adults living with HIV-1 by Eron, Joseph J., Orkin, Chloe, Cunningham, Douglas, Pulido, Federico, Post, Frank A., De Wit, Stéphane, Lathouwers, Erkki, Jezorwski, John, Petrovic, Romana, Brown, Kimberley, Van Landuyt, Erika, Opsomer, Magda, De Wit, S., Florence, E., Van Wijngaerden, E., Vandercam, B., Brunetta, J., Klein, M., Murphy, D., Rachlis, A., Shafran, S., Walmsley, S., Ajana, F., Cotte, L., Girardy, P.-M., Katlama, C., Molina, J.-M., Poizot-Martin, I., Raffi, F., Rey, D., Reynes, J., Teicher, E., Yazdanpanah, Y., Gasiorowski, J., Piekarska, A., Witor, A., Arribas, J.R., Perez-Valero, I., Casado, J., Gatell, J.M., Gutierrez, F., Galindo, M.J., Gutierrez, M.D.M., Iribarren, J.A., Knobel, H., Negredo, E., Pineda, J.A., Podzamczer, D., Sogorb, J.Portilla, Pulido, F., Ricart, C., Rivero, A., Santos Gil, I., Blaxhult, A., Flamholc, L., Gisslèn, M., Thalme, A., Rauch, A., Stoeckle, M., Gazzard, B.G., Post, F., Ustianowski, A., Bailey, J., Benson, P., Bhatti, L., Brar, I., Bredeek, U.F., Brinson, C., Dietz, C., Dretler, R., Felizarta, F., Fichtenbaum, C., Gallant, J., Gathe, J., Hagins, D., Henn, S., Henry, W.K., Huhn, G., Lucasti, C., Martorell, C., McDonald, C., Mills, A., Morales-Ramirez, J., Mounzer, K., Nahass, R., Olivet, H., Prelutsky, D., Ramgopal, M., Rashbaum, B., Richmond, G., Ruane, P., Scarsella, A., Scribner, A., Shalit, P., Shamblaw, D., Slim, J., Tashima, K., Ward, D., Wilkin, A., de Vente, J.

“…Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg was investigated through 96 weeks in EMERALD (NCT02269917)…”
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Efficacy and safety of switching from boosted protease inhibitors plus emtricitabine and tenofovir disoproxil fumarate regimens to single-tablet darunavir, cobicistat, emtricitabine, and tenofovir alafenamide at 48 weeks in adults with virologically suppressed HIV-1 (EMERALD): a phase 3, randomised, non-inferiority trial by Orkin, Chloe, Molina, Jean-Michel, Negredo, Eugenia, Arribas, José R, Eron, Joseph J, Van Landuyt, Erika, Lathouwers, Erkki, Hufkens, Veerle, Petrovic, Romana, Vanveggel, Simon, Ajana, F, Arribas, JR, Bailey, J, Benson, P, Bhatti, L, Blaxhult, A, Brar, I, Bredeek, UF, Brinson, C, Brunetta, J, Casado, J, Clarke, A, Conway, B, Cotte, L, de Vente, J, DeJesus, E, Dietz, C, Dretler, R, Eron, J, Fehr, J, Felizarta, F, Flamholc, L, Florence, E, Gallant, J, Gasiorowski, J, Gatell, JM, Gathe, J, Gazzard, BG, Girard, P-M, Gisslèn, M, Gutierrez, F, Gutierrez, MDM, Hagins, D, Halota, W, Henn, S, Henry, WK, Horban, A, Huhn, G, Iribarren, JA, Jain, M, Johnson, MA, Katlama, C, Klein, M, Knobel, H, Lucasti, C, Martorell, C, McDonald, C, Mills, A, Molina, J-M, Morales-Ramirez, J, Mounzer, K, Moutschen, M, Murphy, D, Nahass, R, Negredo, E, Olivet, H, Orkin, C, Osiyemi, O, Perez-Valero, I, Pineda, JA, Podzamczer, D, Portilla Sogorb, J, Post, F, Prelutsky, D, Pulido, F, Rachlis, A, Raffi, F, Rashbaum, B, Rauch, A, Rey, D, Reynes, J, Ricart, C, Richmond, G, Rivero, A, Ruane, P, Gil, I Santos, Scarsella, A, Shafran, S, Shalit, P, Shamblaw, D, Slim, J, Stoeckle, M, Tashima, K, Ustianowski, A, Van Wijngaerden, E, Vandercam, B, Walmsley, S, Wilkin, A, Witor, A, Yazdanpanah, Y

“…Simplified regimens with reduced pill burden and fewer side-effects are desirable for people living with HIV. We investigated the efficacy and safety of…”
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An intersectional analysis of sociodemographic disparities in Covid-19 vaccination: A nationwide register-based study in Sweden by Spetz, M., Lundberg, L., Nwaru, C., Li, H., Santosa, A., Ng, N., Leach, S., Gisslén, M., Hammar, N., Nyberg, F., Rosvall, M.

“…Studies on sociodemographic disparities in Covid-19 vaccination uptake in the general population are still limited and mostly focused on older adults. This…”
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Sweden, the first country to achieve the Joint United Nations Programme on HIV/AIDS (UNAIDS)/World Health Organization (WHO) 90‐90‐90 continuum of HIV care targets by Gisslén, M, Svedhem, V, Lindborg, L, Flamholc, L, Norrgren, H, Wendahl, S, Axelsson, M, Sönnerborg, A

“…Objectives The Joint United Nations Programme on HIV/AIDS (UNAIDS)/World Health Organization (WHO) 90‐90‐90 goals propose that 90% of all people living with…”
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Severe multisystem inflammatory syndrome (MIS-C/A) after confirmed SARS-CoV-2 infection: a report of four adult cases by Sansone, M, Studahl, M, Berg, S, Gisslén, M, Sundell, N

“…Multisystem inflammatory syndrome (MIS) triggered by a recent SARS-Cov-2 infection has been recognised worldwide. Although predominantly affecting children…”
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Updated research nosology for HIV-associated neurocognitive disorders by ANTINORI, A, ARENDT, G, GISSLEN, M, GRANT, I, HEATON, R. K, JOSEPH, J, MARDER, K, MARRA, C. M, MCARTHUR, J. C, NUNN, M, PRICE, R. W, PULLIAM, L, BECKER, J. T, ROBERTSON, K. R, SACKTOR, N, VALCOUR, V, WOJNA, V. E, BREW, B. J, BYRD, D. A, CHERNER, M, CLIFFORD, D. B, CINQUE, P, EPSTEIN, L. G, GOODKIN, K

“…In 1991, the AIDS Task Force of the American Academy of Neurology published nomenclature and research case definitions to guide the diagnosis of neurologic…”
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Is low‐level HIV‐1 viraemia associated with elevated levels of markers of immune activation, coagulation and cardiovascular disease? by Elvstam, O, Medstrand, P, Jansson, M, Isberg, PE, Gisslén, M, Björkman, P

“…Objectives The clinical significance of low‐level viraemia (LLV) during antiretroviral therapy (ART) is debated. We retrospectively investigated longitudinal…”
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Antiretroviral treatment reduces increased CSF neurofilament protein (NFL) in HIV-1 infection by MELLGREN, A, PRICE, R. W, HAGBERG, L, ROSENGREN, L, BREW, B. J, GISSLEN, M

“…Increased levels of the light-chain neurofilament protein (NFL) in CSF provide a marker of CNS injury in several neurodegenerative disorders and have been…”
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Association between SARS-CoV-2 vaccination and healthcare contacts for menstrual disturbance and bleeding in women before and after menopause: nationwide, register based cohort study by Ljung, Rickard, Xu, YiYi, Sundström, Anders, Leach, Susannah, Hallberg, Ebba, Bygdell, Maria, Larsson, Maria, Arthurson, Veronica, Gisslén, Magnus, Gedeborg, Rolf, Nyberg, Fredrik

“…To evaluate the risks of any menstrual disturbance and bleeding following SARS-CoV-2 vaccination in women who are premenopausal or postmenopausal. A…”
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Increased brain-predicted aging in treated HIV disease by Cole, James H, Underwood, Jonathan, Caan, Matthan W.A, De Francesco, Davide, van Zoest, Rosan A, Leech, Robert, Wit, Ferdinand W.N.M, Portegies, Peter, Geurtsen, Gert J, Schmand, Ben A, Schim van der Loeff, Maarten F, Franceschi, Claudio, Sabin, Caroline A, Majoie, Charles B.L.M, Winston, Alan, Reiss, Peter, Sharp, David J

“…OBJECTIVE:To establish whether HIV disease is associated with abnormal levels of age-related brain atrophy, by estimating apparent brain age using neuroimaging…”
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A Capture-Recapture-based Ascertainment Probability Weighting Method for Effect Estimation With Under-ascertained Outcomes by Bonander, Carl, Nilsson, Anton, Li, Huiqi, Sharma, Shambhavi, Nwaru, Chioma, Gisslén, Magnus, Lindh, Magnus, Hammar, Niklas, Björk, Jonas, Nyberg, Fredrik

“…Outcome under-ascertainment, characterized by the incomplete identification or reporting of cases, poses a substantial challenge in epidemiologic research…”
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Viral co-infection, autoimmunity, and CSF HIV antibody profiles in HIV central nervous system escape by Hawes, I.A., Alvarenga, B.D., Browne, W., Wapniarski, A., Dandekar, R., Bartley, C.M., Sowa, G.M., DeRisi, J.L., Cinque, P., Dravid, A.N., Pleasure, S.J., Gisslen, M., Price, R.W., Wilson, M.R.

“…Antiretroviral therapy (ART) suppresses plasma and cerebrospinal fluid (CSF) HIV replication. Neurosymptomatic (NS) CSF escape is a rare exception in which CNS…”
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Early unrecognised SARS-CoV-2 introductions shaped the first pandemic wave, Sweden, 2020 by Dyrdak, Robert, Hodcroft, Emma B, Broddesson, Sandra, Grabbe, Malin, Franklin, Hildur, Gisslén, Magnus, Holm, Maricris E, Lindh, Magnus, Nederby-Öhd, Joanna, Ringlander, Johan, Sundqvist, Martin, Neher, Richard A, Albert, Jan

“…BackgroundDespite the unprecedented measures implemented globally in early 2020 to prevent the spread of SARS-CoV-2, Sweden, as many other countries,…”
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The impact of Covid-19 in patients with chronic myeloid leukemia—a nationwide population-based study by Dahlén, Torsten, Flygt, Hjalmar, Lübking, Anna, Olsson-Strömberg, Ulla, Wennström, Lovisa, Dreimane, Arta, Själander, Anders, Leach, Susannah, Gisslén, Magnus, Li, Huiqi, Höglund, Martin, Stenke, Leif, Nyberg, Fredrik

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Severe COVID‐19 in people 55 and older during the first year of the pandemic in Sweden by Rosengren, Annika, Lundberg, Christina E., Söderberg, Mia, Santosa, Ailiana, Edqvist, Jon, Lindgren, Martin, Åberg, Maria, Gisslén, Magnus, Robertson, Josefina, Cronie, Ottmar, Sattar, Naveed, Lagergren, Jesper, Brandén, Maria, Björk, Jonas, Adiels, Martin

“…Background Exposure to many contacts is the main risk factor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, while risk of serious…”
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Response to: ‘How helpful are the European AIDS Clinical Society cognitive screening questions in predicting cognitive impairment in an aging, well‐treated HIV‐positive population?’ by Winston, A, Cotter, A, Gisslen, M, Mallon, PWG, Cinque, P

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Swedish Covid-19 Investigation for Future Insights - A Population Epidemiology Approach Using Register Linkage (SCIFI-PEARL) by Nyberg, Fredrik, Franzén, Stefan, Lindh, Magnus, Vanfleteren, Lowie, Hammar, Niklas, Wettermark, Björn, Sundström, Johan, Santosa, Ailiana, Björck, Staffan, Gisslén, Magnus

“…In response to the Covid-19 pandemic, we designed and initiated a nationwide linked multi-register, regularly updated, observational study for timely response…”
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The social patterning of Covid-19 vaccine uptake in older adults: A register-based cross-sectional study in Sweden by Spetz, Malin, Lundberg, Lisa, Nwaru, Chioma, Li, Huiqi, Santosa, Ailiana, Leach, Susannah, Gisslén, Magnus, Hammar, Niklas, Rosvall, Maria, Nyberg, Fredrik

“…A broad vaccination coverage is crucial for preventing the spread of Covid-19 and reduce serious illness or death. The aim of this study was to examine social…”
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Risk of COVID-19 hospitalisation by HIV-status and SARS-CoV-2 vaccination status during pre- and post-Omicron era in a national register-based cohort study in Sweden by Killander Möller, Isabela, Hedberg, Pontus, Wagner, Philippe, Lindahl, Hannes, Nyström, Sofia, Blixt, Lisa, Eketorp Sylvan, Sandra, Nilsdotter-Augustinsson, Åsa, Österborg, Anders, Fredrikson, Mats, Hansson, Lotta, Kahn, Fredrik, Sparén, Pär, Gisslén, Magnus, Nauclér, Pontus, Bergman, Peter, Aleman, Soo, Carlander, Christina

“…Data on the outcomes of COVID-19 in people living with HIV (PLHIV), specifically in relation to vaccination status, are lacking during the Omicron era. This…”
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Cohort profile: InfCareHIV, a prospective registry-based cohort study of people with diagnosed HIV in Sweden by Carlander, Christina, Brännström, Johanna, Månsson, Fredrik, Elvstam, Olof, Albinsson, Pernilla, Blom, Simon, Mattsson, Lena, Hovmöller, Sanne, Norrgren, Hans, Mellgren, Åsa, Svedhem, Veronica, Gisslén, Magnus, Sönnerborg, Anders

“…PurposeThe Swedish InfCareHIV cohort was established in 2003 to ensure equal and effective care of people living with HIV (PLHIV) and enable long-term…”
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