Search Results - "Gispen, W H"

Hippocampal Synaptic Plasticity Involves Competition between Ca2+/Calmodulin-Dependent Protein Kinase II and Postsynaptic Density 95 for Binding to the NR2A Subunit of the NMDA Receptor by Gardoni, F, Schrama, L. H, Kamal, A, Gispen, W. H, Cattabeni, F, Di Luca, M

“…NMDA receptor, Ca(2+)/calmodulin-dependent protein kinase II (alphaCaMKII), and postsynaptic density 95 (PSD-95) are three major components of the PSD…”
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Injury-Induced Class 3 Semaphorin Expression in the Rat Spinal Cord by De Winter, F., Oudega, M., Lankhorst, A.J., Hamers, F.P., Blits, B., Ruitenberg, M.J., Pasterkamp, R.J., Gispen, W.H., Verhaagen, J.

“…In this study we evaluate the expression of all members of the class 3 semaphorins and their receptor components following complete transection and contusion…”
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Distribution of glutamate transporters in the hippocampus of patients with pharmaco-resistant temporal lobe epilepsy by PROPER, E. A, HOOGLAND, G, DE GRAAN, P. N. E, KAPPEN, S. M, JANSEN, G. H, RENSEN, M. G. A, SCHRAMA, L. H, VAN VEELEN, C. W. M, VAN RIJEN, P. C, VAN NIEUWENHUIZEN, O, GISPEN, W. H

“…In patients suffering from temporal lobe epilepsy (TLE), increased extracellular glutamate levels in the epileptogenic hippocampus both during and after…”
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Learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: interaction of diabetes and ageing by KAMAL, A, BIESSELS, G. J, DUIS, S. E. J, GISPEN, W. H

“…Diabetes mellitus leads to functional and structural changes in the brain which appear to be most pronounced in the elderly. Because the pathogenesis of brain…”
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Effects of streptozotocin‐diabetes on the hippocampal NMDA receptor complex in rats by Gardoni, F., Kamal, A., Bellone, C., Biessels, G. J., Ramakers, G. M. J., Cattabeni, F., Gispen, W. H., Di Luca, M.

“…In animal models of diabetes mellitus, such as the streptozotocin‐diabetic rat (STZ‐rat), spatial learning impairments develop in parallel with a reduced…”
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Cognition and synaptic plasticity in diabetes mellitus by Gispen, Willem Hendrik, Biessels, Geert-Jan

“…Diabetes mellitus is associated with cognitive deficits and an increased risk of dementia, particularly in the elderly. These deficits are paralleled by…”
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Hippocampal synaptic plasticity in streptozotocin-diabetic rats: impairment of long-term potentiation and facilitation of long-term depression by Kamal, A., Biessels, G.-J., Urban, I.J.A., Gispen, W.H.

“…Streptozotocin-diabetic rats, an animal model for diabetes mellitus, show learning deficits and impaired long-term potentiation in the CA1-field of the…”
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Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats by Biessels, G. J., Kamal, A., Ramakers, G. M., Urban, I. J., Spruijt, B. M., Erkelens, D. W., Gispen, W. H.

“…Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats. G J Biessels , A Kamal , G M Ramakers , I J Urban , B M Spruijt , D…”
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Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries by Hamers, F P, Lankhorst, A J, van Laar, T J, Veldhuis, W B, Gispen, W H

“…Analysis of locomotion is an important tool in the study of peripheral and central nervous system damage. Most locomotor scoring systems in rodents are based…”
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Ethology and neurobiology of grooming behavior by Spruijt, B M, van Hooff, J A, Gispen, W H

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Peripheral and central neurologic complications in type 2 diabetes mellitus: No association in individual patients by Manschot, S.M, Biessels, G.J, Rutten, G.E.H.M, Kessels, R.C.P, Gispen, W.H, Kappelle, L.J

“…Abstract Diabetes mellitus is associated with end-organ complications in the peripheral and central nervous system. It is unknown if these complications share…”
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Diabetes mellitus concomitantly facilitates the induction of long-term depression and inhibits that of long-term potentiation in hippocampus by Artola, A., Kamal, A., Ramakers, G. M. J., Biessels, G. J., Gispen, W. H.

“…Memory impairments, which occur regularly across species as a result of ageing, disease (such as diabetes mellitus) and psychological insults, constitute a…”
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NMDA receptor subunits are modified transcriptionally and post-translationally in the brain of streptozotocin-diabetic rats by DI LUCA, M, RUTS, L, GARDONI, F, CATTABENI, F, BIESSELS, G. J, GISPEN, W. H

“…Moderate disturbances of learning and memory were recognized as a complication of diabetes mellitus in patients. The streptozotocin-diabetic rat, an animal…”
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Collagen Containing Neurotrophin-3 (NT-3) Attracts Regrowing Injured Corticospinal Axons in the Adult Rat Spinal Cord and Promotes Partial Functional Recovery by Houweling, D.A., Lankhorst, A.J., Gispen, W.H., Bär, P.R., Joosten, E.A.J.

“…During development, neurotrophic factors play an important role in the guidance and outgrowth of axons. Our working hypothesis is that neurotrophic factors…”
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Cerebral function in diabetes mellitus by BIESSELS, G. J, KAPPELLE, A. C, BRAVENBOER, B, ERKELENS, D. W, GISPEN, W. H

“…Diabetes mellitus is a common metabolic disorder associated with chronic complications such as nephropathy, angiopathy, retinopathy and peripheral neuropathy…”
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Immunohistochemical characterization of mossy fibre sprouting in the hippocampus of patients with pharmaco-resistant temporal lobe epilepsy by Proper, E. A., Oestreicher, A. B., Jansen, G. H., Veelen, C. W. M. v., van Rijen, P. C., Gispen, W. H., de Graan, P. N. E.

“…Hippocampal sclerosis (HS) is a common derangement in many patients with temporal lobe epilepsy. As a result of neuronal cell loss in the hilar region of the…”
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Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: effects of insulin treatment by Biessels, Geert-Jan, Kamal, Amer, Urban, Ivan J.A, Spruijt, Berrie M, Erkelens, D.Willem, Gispen, Willem Hendrik

“…Streptozotocin-diabetic rats express deficits in water maze learning and hippocampal synaptic plasticity. The present study examined whether these deficits…”
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Insulin inhibits extracellular regulated kinase 1/2 phosphorylation in a phosphatidylinositol 3‐kinase (PI3) kinase‐dependent manner in Neuro2a cells by Van Der Heide, L. P., Hoekman, M. F., Biessels, G. J., Gispen, W. H.

“…Insulin signalling is well studied in peripheral tissue, but not in neuronal tissue. To gain more insight into neuronal insulin signalling we examined protein…”
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Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase by MORITZ, A, DE GRAAN, P. N. E, GISPEN, W. H, WIRTZ, K. W. A

“…The lipid dependence of phosphatidylinositol-4-phosphate (PIP) kinase purified from bovine brain membranes was investigated. In the assay used, PIP-Triton…”
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Antagonism of the Melanocortin System Reduces Cold and Mechanical Allodynia in Mononeuropathic Rats by Vrinten, Dorien H, Gispen, Willem Hendrik, Groen, Gerbrand J, Adan, Roger A. H

“…The presence of both pro-opiomelanocortin-derived peptides and melanocortin (MC) receptors in nociception-associated areas in the spinal cord suggests that, at…”
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