Search Results - "Gish, Joseph S"

Structure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor by Ronayne, Estelle K, Peters, Shaun C, Gish, Joseph S, Wilson, Celena, Spencer, H Trent, Doering, Christopher B, Lollar, Pete, Spiegel, Jr, P Clint, Childers, Kenneth C

“…Factor VIII (fVIII) is a procoagulant protein that binds to activated factor IX (fIXa) on platelet surfaces to form the intrinsic tenase complex. Due to the…”
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Structure of blood coagulation factor VIII in complex with an anti–C1 domain pathogenic antibody inhibitor by Gish, Joseph S., Jarvis, Lexi, Childers, Kenneth C., Peters, Shaun C., Garrels, Connor S., Smith, Ian W., Spencer, H. Trent, Doering, Christopher B., Lollar, Pete, Spiegel, P. Clint

“…Antibody inhibitor development in hemophilia A represents the most significant complication resulting from factor VIII (fVIII) replacement therapy. Recent…”
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