Search Results - "Girones, Daniel"

Cationic Geminoid Peptide Amphiphiles Inhibit DENV2 Protease, Furin, and Viral Replication by Damen, Mark, Izidoro, Mario A, Okamoto, Debora N, Oliveira, Lilian C G, Amatdjais-Groenen, Helene I V, van Dongen, Stijn F M, van Cleef, Koen W R, van Rij, Ronald P, Dieteren, Cindy E J, Gironés, Daniel, van Buuren, Bernd N M, Martina, Byron E E, Osterhaus, Albert D M E, Juliano, Luiz, Scholte, Bob J, Feiters, Martin C

“…Dengue is an important arboviral infectious disease for which there is currently no specific cure. We report gemini-like (geminoid) alkylated amphiphilic…”
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Orthoflaviviral Inhibitors in Clinical Trials, Preclinical In Vivo Efficacy Targeting NS2B-NS3 and Cellular Antiviral Activity via Competitive Protease Inhibition by Cavina, Lorenzo, Bouma, Mathijs J, Gironés, Daniel, Feiters, Martin C

“…Orthoflaviviruses, including zika (ZIKV), West Nile (WNV), and dengue (DENV) virus, induce severely debilitating infections and contribute significantly to the…”
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Synthesis of 2,6-Bridged Piperazine-3-ones by N-Acyliminium Ion Chemistry by Veerman, Johan J. N, Bon, Robin S, Hue, Bui T. B, Girones, Daniel, Rutjes, Floris P. J. T, van Maarseveen, Jan H, Hiemstra, Henk

“…Several 2-substituted and 2,5-disubstituted piperazine-3,6-diones were synthesized starting from readily available α-amino acids. After activation of a lactam…”
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2′-Modified Neamine Analogues from Thiomannosides through Glycosidation-Stereoinversion by Gironés, Daniel, Hanckmann, Marcel, Rutjes, Floris P. J. T., van Delft, Floris L.

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2′-Modified Neamine Analogues from Thiomannosides through Glycosidation-Stereoinversion by Gironés, Daniel, Hanckmann, Marcel, Rutjes, Floris P. J. T., van Delft, Floris L.

“…Conveniently protected neamine analogues were synthesized with a free 2′‐OH group for further functionalization. An approach was investigated involving a…”
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