Search Results - "Giraudo, G."

Endogenous Species of Mammalian Nonmuscle Myosin IIA and IIB Include Activated Monomers and Heteropolymers by Shutova, Maria S., Spessott, Waldo A., Giraudo, Claudio G., Svitkina, Tatyana

“…Class II myosins generate contractile forces in cells by polymerizing into bipolar filaments and pulling on anchored actin filaments. Nonmuscle myosin II…”
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Clamping Mechanism Involved in SNARE-Dependent Exocytosis by Giraudo, Claudio G, Eng, William S, Melia, Thomas J, Rothman, James E

“…During neurotransmitter release at the synapse, influx of calcium ions stimulates the release of neurotransmitter. However, the mechanism by which synaptic…”
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Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion by Giraudo, Claudio G, Garcia-Diaz, Alejandro, Eng, William S, Chen, Yuhang, Hendrickson, Wayne A, Melia, Thomas J, Rothman, James E

“…Membrane fusion between vesicles and target membranes involves the zippering of a four-helix bundle generated by constituent helices derived from target- and…”
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Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state by Rothman, James E, Li, Feng, Pincet, Frédéric, Perez, Eric, Giraudo, Claudio G, Tareste, David

“…The SNARE-binding protein complexin (CPX) can both facilitate and inhibit membrane fusion, which has been puzzling. Using the Surface Forces Apparatus (SFA)…”
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Particle beam microstructure reconstruction and coincidence discrimination in PET monitoring for hadron therapy by Kostara, E, Sportelli, G, Belcari, N, Camarlinghi, N, Cerello, P, Del Guerra, A, Ferrero, V, Fiorina, E, Giraudo, G, Morrocchi, M, Pennazio, F, Pullia, M, Rivetti, A, Rolo, M D, Rosso, V, Wheadon, R, Bisogni, M G

“…Positron emission tomography is one of the most mature techniques for monitoring the particles range in hadron therapy, aiming to reduce treatment…”
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A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion by Rothman, James E, Krishnakumar, Shyam S, Radoff, Daniel T, Kümmel, Daniel, Giraudo, Claudio G, Li, Feng, Khandan, Lavan, Baguley, Stephanie Wood, Coleman, Jeff, Reinisch, Karin M, Pincet, Frederic

“…Comparison of the prefusion and postfusion structures of complexin associated with SNAREs reveals a conformational switch in complexin, which is triggered by…”
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Full-beam performances of a PET detector with synchrotron therapeutic proton beams by Piliero, M A, Pennazio, F, Bisogni, M G, Camarlinghi, N, Cerello, P G, Del Guerra, A, Ferrero, V, Fiorina, E, Giraudo, G, Morrocchi, M, Peroni, C, Pirrone, G, Sportelli, G, Wheadon, R

“…Treatment quality assessment is a crucial feature for both present and next-generation ion therapy facilities. Several approaches are being explored, based on…”
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STXBP2-R190C Variant in a Patient With Neonatal Hemophagocytic Lymphohistiocytosis (HLH) and G6PD Deficiency Reveals a Critical Role of STXBP2 Domain 2 on Granule Exocytosis by Benavides, Nathalia, Spessott, Waldo A, Sanmillan, Maria L, Vargas, Marcelo, Livingston, Mylynda S, Erickson, Nissa, Pozos, Tamara C, McCormick, Margaret E, Scharrig, Emilia, Messinger, Yoav H, Giraudo, Claudio G

“…Neonatal hemophagocytic lymphohistiocytosis (HLH) is a medical emergency that can be associated with significant morbidity and mortality. Often these patients…”
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Laparoscopic versus open surgery for extraperitoneal rectal cancer : A prospective comparative study by MORINO, M, ALLAIX, M. E, GIRAUDO, G, CORNO, F, GARRONE, C

“…The role of laparoscopic resection (LR) in the management of extraperitoneal rectal cancer still is unclear. This study aimed to compare perioperative and…”
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Robot-assisted vs laparoscopic adrenalectomy: A prospective randomized controlled trial by MORINO, M, BENINCA, G, GIRAUDO, G, DEL GENIO, G. M, REBECCHI, F, GARRONE, C

“…The aim of this study was to assess the benefits and disadvantages of robot-assisted laparoscopic surgery for disorders of the adrenal gland in terms of…”
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SNAREs can promote complete fusion and hemifusion as alternative outcomes by Giraudo, Claudio G, Hu, Chuan, You, Daoqi, Slovic, Avram M, Mosharov, Eugene V, Sulzer, David, Melia, Thomas J, Rothman, James E

“…Using a cell fusion assay, we show here that in addition to complete fusion SNAREs also promote hemifusion as an alternative outcome. Approximately 65% of…”
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Ganglioside Glycosyltransferases Organize in Distinct Multienzyme Complexes in CHO-K1 Cells by Giraudo, Claudio G., Maccioni, Hugo J.F.

“…The synthesis of gangliosides is compartmentalized in the Golgi complex. In most cells, glycosylation of LacCer, GM3, and GD3 to form higher order species…”
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Monte Carlo simulation tool for online treatment monitoring in hadrontherapy with in-beam PET: A patient study by Fiorina, E., Ferrero, V., Pennazio, F., Baroni, G., Battistoni, G., Belcari, N., Cerello, P., Camarlinghi, N., Ciocca, M., Del Guerra, A., Donetti, M., Ferrari, A., Giordanengo, S., Giraudo, G., Mairani, A., Morrocchi, M., Peroni, C., Rivetti, A., Da Rocha Rolo, M.D., Rossi, S., Rosso, V., Sala, P., Sportelli, G., Tampellini, S., Valvo, F., Wheadon, R., Bisogni, M.G.

“…[Display omitted] •Range monitoring is necessary to fully exploit hadrontherapy advantages.•The Monte Carlo (MC) simulation tool for the INSIDE in-beam PET…”
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Extended-Synaptotagmin-1 and -2 control T cell signaling and function by Benavides, Nathalia, Giraudo, Claudio G

“…Upon T-cell activation, the levels of the secondary messenger diacylglycerol (DAG) at the plasma membrane need to be controlled to ensure appropriate T-cell…”
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Endoplasmic reticulum export of glycosyltransferases depends on interaction of a cytoplasmic dibasic motif with Sar1 by Giraudo, Claudio G, Maccioni, Hugo J F

“…Membrane proteins exit the endoplasmic reticulum (ER) in COPII-transport vesicles. ER export is a selective process in which transport signals present in the…”
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Distinct Domains of Complexins Bind SNARE Complexes and Clamp Fusion in Vitro by Giraudo, Claudio G., Garcia-Diaz, Alejandro, Eng, William S., Yamamoto, Ai, Melia, Thomas J., Rothman, James E.

“…In regulated exocytosis, the core membrane fusion machinery proteins, the SNARE proteins, are assisted by a group of regulatory factors in order to couple…”
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Physical and Functional Association of Glycolipid N-Acetyl-Galactosaminyl and Galactosyl Transferases in the Golgi Apparatus by Giraudo, Claudio G., Daniotti, Jose L., Hugo J. F. Maccioni

“…Glycolipid glycosyltransferases catalyze the stepwise transfer of monosaccharides from sugar nucleotides to proper glycolipid acceptors. They are Golgi…”
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Elemental fragmentation cross sections for a 16O beam of 400 MeV/u kinetic energy interacting with a graphite target using the FOOT ΔE-TOF detectors by Toppi, M., Sarti, A., Alexandrov, A., Alpat, B., Ambrosi, G., Argirò, S., Diaz, R. A, Barbanera, M., Bartosik, N., Battistoni, G., Belcari, N., Biondi, S., Bisogni, M. G., Bon, M., Bruni, G., Carra, P., Cavanna, F., Cerello, P., Ciarrocchi, E., Clozza, A., Colombi, S., De Lellis, G., De Gregorio, A., Del Guerra, A., De Simoni, M., Di Crescenzo, A., Di Ruzza, B., Donetti, M., Dong, Y., Durante, M., Ferrero, V., Fiandrini, E., Finck, C., Fiorina, E., Fischetti, M., Francesconi, M., Franchini, M., Franciosini, G., Galati, G., Galli, L., Giraudo, G., Hetzel, R., Iarocci, E., Ionica, M., Iuliano, A., Kanxheri, K., Kraan, A.C., La Tessa, C., Laurenza, M., Lauria, A., Torres, E. L, Marafini, M., Massa, M., Massimi, C., Mattei, I., Meneghetti, A., Mengarelli, A., Mirabelli, R., Moggi, A., Montesi, M.C., Morone, M.C., Morrocchi, M., Muraro, S., Murtas, F., Muscato, A., Pastore, A., Pastrone, N., Patera, V., Pennazio, F., Peverini, F., Placidi, P., Pullia, M., Ramello, L., Reidel, C., Ridolfi, R., Rosso, V., Sanelli, C., Sartorelli, G., Sato, O., Savazzi, S., Scavarda, L., Schiavi, A., Schuy, C., Scifoni, E., Sciubba, A., Sécher, A., Selvi, M., Servoli, L., Silvestre, G., Sitta, M., Spighi, R., Spiriti, E., Sportelli, G., Stahl, A., Tomassini, S., Tommasino, F., Tioukov, V., Traini, G., Trigilio, A., Valle, S.M.

“…The study of nuclear fragmentation plays a central role in many important applications: from the study of Particle Therapy (PT) up to radiation protection for…”
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P.13.6 TRANSANAL ENDOSCOPIC MICROSURGERY VERSUS LAPAROSCOPIC TOTAL MESORECTAL EXCISION FOR SELECTED T2N0 RECTAL CANCER by Allaix, M.E, Arezzo, A, Giraudo, G, Morino, M

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RHOG: Rac1-ing up another HLH gene by Nichols, Kim E., Giraudo, Claudio G.

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