Search Results - "Giraudi, Pablo"
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Natural Compounds for Counteracting Nonalcoholic Fatty Liver Disease (NAFLD): Advantages and Limitations of the Suggested Candidates
Published in International journal of molecular sciences (02-03-2022)“…The booming prevalence of nonalcoholic fatty liver disease (NAFLD) in adults and children will threaten the health system in the upcoming years. The "multiple…”
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Silybin Modulates Collagen Turnover in an In Vitro Model of NASH
Published in Molecules (Basel, Switzerland) (02-04-2019)“…Silybin has been proposed as a treatment for nonalcoholic steatohepatitis (NASH). In this study, we assessed the effect of Silybin in a well-established in…”
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Effects of Oral Administration of Silymarin in a Juvenile Murine Model of Non-alcoholic Steatohepatitis
Published in Nutrients (12-09-2017)“…The increasing prevalence of non-alcoholic fatty liver disease (NAFLD) in adolescents is challenging the global care system. No therapeutic strategies have…”
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Differentiation between stages of non-alcoholic fatty liver diseases using surface-enhanced Raman spectroscopy
Published in Analytica chimica acta (08-05-2020)“…Non-alcoholic fatty liver disease (NAFLD) is a chronic disorder progressing from an initial benign accumulation of fat (NAFL) towards steatohepatitis (NASH), a…”
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Taste perception and expression in stomach of bitter taste receptor tas2r38 in obese and lean subjects
Published in Appetite (01-11-2021)“…Differences in taste perception have been related to eating behavior, nutritional status, and diseases. Recently, taste receptors have been identified in…”
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The interplay between hepatic stellate cells and hepatocytes in an in vitro model of NASH
Published in Toxicology in vitro (01-10-2015)“…•Global obesity epidemic dramatically increased the fatty liver disease prevalence.•In vitro models mimic liver microenvironment reproducing cellular responses…”
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Genome-wide DNA methylation and transcriptomic analysis of liver tissues subjected to early ischemia/reperfusion injury upon human liver transplantation
Published in Annals of hepatology (01-07-2024)“…Epigenetic changes represent a mechanism connecting external stresses with long-term modifications of gene expression programs. In solid organ transplantation,…”
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Ficolin-2 Plasma Level Assesses Liver Fibrosis in Non-Alcoholic Fatty Liver Disease
Published in International journal of molecular sciences (04-03-2022)“…Fibrosis is the strongest predictor for disease-specific mortality in non-alcoholic fatty liver diseases (NAFLD), but the need for liver biopsy limits its…”
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Occult hepatitis B virus infection predicts non‐alcoholic steatohepatitis in severely obese individuals from Italy
Published in Liver international (01-07-2020)“…Background & Aims Obesity is associated with non‐alcoholic fatty liver (NAFL), which may progress towards non‐alcoholic steatohepatitis (NASH), cirrhosis and…”
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Proteome profiling identifies circulating biomarkers associated with hepatic steatosis in subjects with Prader-Willi syndrome
Published in Frontiers in endocrinology (Lausanne) (15-11-2023)“…Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by loss of expression of paternal chromosome 15q11.2-q13 genes. Individuals with PWS…”
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Gender Differences in the Impact of a High-Fat, High-Sugar Diet in Skeletal Muscles of Young Female and Male Mice
Published in Nutrients (13-05-2024)“…In the context of the increasing number of obese individuals, a major problem is represented by obesity and malnutrition in children. This condition is mainly…”
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The potential role of omentin-1 in obesity-related metabolic dysfunction-associated steatotic liver disease: evidence from translational studies
Published in Journal of translational medicine (11-12-2023)“…Obesity, characterized by visceral adipose tissue (VAT) expansion, is closely associated with metabolic dysfunction-associated steatotic liver disease (MASLD)…”
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Modifications of IGF2 and EGFR plasma protein concentrations in NAFLD patients after bariatric surgery
Published in International Journal of Obesity (01-02-2021)“…Background Nonalcoholic fatty liver disease (NAFLD) is strictly associated with the epidemic of obesity and is becoming the most prevalent liver disease…”
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Network Analysis for the Discovery of Common Oncogenic Biomarkers in Liver Cancer Experimental Models
Published in Biomedicines (25-01-2023)“…Hepatocellular carcinoma (HCC) is a malignancy marked by heterogeneity. This study aimed to discover target molecules for potential therapeutic efficacy that…”
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Characterization of Circulating Protein Profiles in Individuals with Prader-Willi Syndrome and Individuals with Non-Syndromic Obesity
Published in Journal of clinical medicine (25-09-2024)“…Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by distinctive physical, cognitive, and behavioral manifestations, coupled with profound…”
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Diagnostic management of nonalcoholic fatty liver disease: a transformational period in the development of diagnostic and predictive tools-a narrative review
Published in Annals of translational medicine (01-04-2021)“…NAFLD is an emerging healthcare epidemic that is causing predictable adverse consequences for healthcare systems, societies and individuals. Whilst NAFLD is…”
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The importance of the interaction between hepatocyte and hepatic stellate cells in fibrogenesis induced by fatty accumulation
Published in Experimental and molecular pathology (01-02-2015)“…Non-alcoholic fatty liver disease is characterized by an initial accumulation of triglycerides that can progress to non-alcoholic steatohepatitis, which can…”
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Rescue of bilirubin‐induced neonatal lethality in a mouse model of Crigler‐Najjar syndrome type I by AAV9‐mediated gene transfer
Published in The FASEB journal (01-03-2012)“…Crigler‐Najjar type I (CNI) syndrome is a recessively inherited disorder characterized by severe unconjugated hyperbilirubinemia caused by uridine…”
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Kinetics and Specificity of Feline Leukemia Virus Subgroup C Receptor (FLVCR) Export Function and Its Dependence on Hemopexin
Published in The Journal of biological chemistry (10-09-2010)“…The feline leukemia virus subgroup C receptor (FLVCR) is a heme export protein that is required for proerythroblast survival and facilitates macrophage heme…”
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Optimization of Point-Shear Wave Elastography by Skin-to-Liver Distance to Assess Liver Fibrosis in Patients Undergoing Bariatric Surgery
Published in Diagnostics (Basel) (07-10-2020)“…Obesity is a primary limiting factor in liver stiffness measurement (LSM). The impact of obesity has always been evaluated in terms of body mass index (BMI),…”
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