Search Results - "Giraud, Sebastien"

Estradiol inhibits ongoing autoimmune neuroinflammation and NFκB-dependent CCL2 expression in reactive astrocytes by Giraud, Sébastien N, Caron, Cécile M, Pham-Dinh, Danielle, Kitabgi, Patrick, Nicot, Arnaud B

“…Astroglial reactivity associated with increased production of NFκB-dependent proinflammatory molecules is an important component of the pathophysiology of…”
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In Vitro/Ex Vivo Models for the Study of Ischemia Reperfusion Injury during Kidney Perfusion by Giraud, Sebastien, Thuillier, Raphaël, Cau, Jérome, Hauet, Thierry

“…Oxidative stress is a key element of ischemia-reperfusion injury, occurring during kidney preservation and transplantation. Current options for kidney graft…”
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Individual and Combined Impact of Oxygen and Oxygen Transporter Supplementation during Kidney Machine Preservation in a Porcine Preclinical Kidney Transplantation Model by Kasil, Abdelsalam, Giraud, Sebastien, Couturier, Pierre, Amiri, Akbar, Danion, Jerome, Donatini, Gianluca, Matillon, Xavier, Hauet, Thierry, Badet, Lionel

“…Marginal kidney graft preservation in machine perfusion (MP) is well-established. However, this method requires improvement in order to mitigate oxidative…”
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A Sodium Oxalate-Rich Diet Induces Chronic Kidney Disease and Cardiac Dysfunction in Rats by Crestani, Thayane, Crajoinas, Renato O., Jensen, Leonardo, Dima, Leno L., Burdeyron, Perrine, Hauet, Thierry, Giraud, Sebastien, Steichen, Clara

“…Chronic kidney disease (CKD) is a worldwide public health issue affecting 14% of the general population. However, research focusing on CKD mechanisms/treatment…”
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Study of the Role of the Tyrosine Kinase Receptor MerTK in the Development of Kidney Ischemia-Reperfusion Injury in RCS Rats by Pelé, Thomas, Giraud, Sebastien, Joffrion, Sandrine, Ameteau, Virginie, Delwail, Adriana, Goujon, Jean-Michel, Macchi, Laurent, Hauet, Thierry, Dkhissi, Fatima, Benzakour, Omar

“…Renal ischaemia reperfusion (I/R) triggers a cascade of events including oxidative stress, apoptotic body and microparticle (MP) formation as well as an acute…”
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High Throughput Proteomic Exploration of Hypothermic Preservation Reveals Active Processes within the Cell Associated with Cold Ischemia Kinetic by Pasini-Chabot, Ophélie, Vincent, Julia, Le Pape, Sylvain, Lepoittevin, Maryne, Kaaki, Wassim, Woillard, Jean-Baptiste, Giraud, Sebastien, Bourmeyster, Nicolas, Hauet, Thierry, Thuillier, Raphael

“…The demand for organs to be transplanted increases pressure on procurement centers, to the detriment of organ quality, increasing complications. New…”
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The Optimal PEG for Kidney Preservation: A Preclinical Porcine Study by Giraud, Sebastien, Thuillier, Raphael, Codas, Ricardo, Manguy, Emily, Barrou, Benoit, Valagier, Alexandre, Puichaud, Alexis, Badet, Lionel, Nicolas, Emmanuelle, Eugene, Michel, Hauet, Thierry

“…University of Wisconsin (UW) solution is not optimal for preservation of marginal organs. Polyethylene glycol (PEG) could improve protection. Similarly…”
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Renal Ischemia Tolerance Mediated by eIF5A Hypusination Inhibition Is Regulated by a Specific Modulation of the Endoplasmic Reticulum Stress by Melis, Nicolas, Rubera, Isabelle, Giraud, Sebastien, Cougnon, Marc, Duranton, Christophe, Poet, Mallorie, Jarretou, Gisèle, Thuillier, Raphaël, Counillon, Laurent, Hauet, Thierry, Pellerin, Luc, Tauc, Michel, Pisani, Didier F

“…Through kidney transplantation, ischemia/reperfusion is known to induce tissular injury due to cell energy shortage, oxidative stress, and endoplasmic…”
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The myeloid mineralocorticoid receptor controls inflammatory and fibrotic responses after renal injury via macrophage interleukin-4 receptor signaling by Barrera-Chimal, Jonatan, Estrela, Gabriel R, Lechner, Sebastian M, Giraud, Sébastien, El Moghrabi, Soumaya, Kaaki, Shiem, Kolkhof, Peter, Hauet, Thierry, Jaisser, Frédéric

“…Acute kidney injury induced by ischemia/reperfusion is an independent risk factor for chronic kidney disease. Macrophage recruitment plays an essential role…”
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Endogenous IL-33 Contributes to Kidney Ischemia-Reperfusion Injury as an Alarmin by Ferhat, Maroua, Robin, Aurélie, Giraud, Sébastien, Sena, Sandra, Goujon, Jean-Michel, Touchard, Guy, Hauet, Thierry, Girard, Jean-Philippe, Gombert, Jean-Marc, Herbelin, André, Thierry, Antoine

“…Inflammation is a prominent feature of ischemia-reperfusion injury (IRI), which is characterized by leukocyte infiltration and renal tubular injury. However,…”
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Electron-phonon scattering in topological insulator thin films by Giraud, Sébastien, Kundu, Arijit, Egger, Reinhold

“…We present a theoretical study of electron-phonon scattering effects in thin films made of a strong topological insulator. The phonons are modeled by isotropic…”
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Urine-derived stem/progenitor cells: A focus on their characterization and potential by Burdeyron, Perrine, Giraud, Sébastien, Hauet, Thierry, Steichen, Clara

“…Cell therapy, ., the use of cells to repair an affected tissue or organ, is at the forefront of regenerative and personalized medicine. Among the multiple cell…”
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Oxidative Stress Evaluation in Ischemia Reperfusion Models: Characteristics, Limits and Perspectives by Chazelas, Pauline, Steichen, Clara, Favreau, Frédéric, Trouillas, Patrick, Hannaert, Patrick, Thuillier, Raphaël, Giraud, Sébastien, Hauet, Thierry, Guillard, Jérôme

“…Ischemia reperfusion injury is a complex process consisting of a seemingly chaotic but actually organized and compartmentalized shutdown of cell function, of…”
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Immune response after pig-to-human kidney xenotransplantation: a multimodal phenotyping study by Loupy, Alexandre, Goutaudier, Valentin, Giarraputo, Alessia, Mezine, Fariza, Morgand, Erwan, Robin, Blaise, Khalil, Karen, Mehta, Sapna, Keating, Brendan, Dandro, Amy, Certain, Anaïs, Tharaux, Pierre-Louis, Narula, Navneet, Tissier, Renaud, Giraud, Sébastien, Hauet, Thierry, Pass, Harvey I, Sannier, Aurélie, Wu, Ming, Griesemer, Adam, Ayares, David, Tatapudi, Vasishta, Stern, Jeffrey, Lefaucheur, Carmen, Bruneval, Patrick, Mangiola, Massimo, Montgomery, Robert A

“…Cross-species immunological incompatibilities have hampered pig-to-human xenotransplantation, but porcine genome engineering recently enabled the first…”
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New strategies to optimize kidney recovery and preservation in transplantation by Bon, Delphine, Chatauret, Nicolas, Giraud, Sébastien, Thuillier, Raphael, Favreau, Frédéric, Hauet, Thierry

“…Optimizing kidney preservation is a primary concern in transplantation, particularly in relation to new donor sources, such as expanded criteria donors and…”
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Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney by Cougnon, Marc, Carcy, Romain, Melis, Nicolas, Rubera, Isabelle, Duranton, Christophe, Dumas, Karine, Tanti, Jean-François, Pons, Catherine, Soubeiran, Nicolas, Shkreli, Marina, Hauet, Thierry, Pellerin, Luc, Giraud, Sébastien, Blondeau, Nicolas, Tauc, Michel, Pisani, Didier F.

“…Inhibition of the eukaryotic initiation factor 5A activation by the spermidine analogue GC7 has been shown to protect proximal cells and whole kidneys against…”
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Preservation of Organs to Be Transplanted: An Essential Step in the Transplant Process by Lepoittevin, Maryne, Giraud, Sébastien, Kerforne, Thomas, Barrou, Benoit, Badet, Lionel, Bucur, Petru, Salamé, Ephrem, Goumard, Claire, Savier, Eric, Branchereau, Julien, Battistella, Pascal, Mercier, Olaf, Mussot, Sacha, Hauet, Thierry, Thuillier, Raphael

“…Organ transplantation remains the treatment of last resort in case of failure of a vital organ (lung, liver, heart, intestine) or non-vital organ (essentially…”
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A new preservation solution increases islet yield and reduces graft immunogenicity in pancreatic islet transplantation by SEBASTIEN, Giraud, BLANDINE, Claire, MIHEL, Eugene, PATRICE, Debre, FRANJOIS, Richard, BENOIF, Barrou

“…The aim of the study was to test a new preservation solution containing polyethylene glycol (S.C.O.T. solution) as pancreatic islet isolation medium both to…”
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Defining the optimal duration for normothermic regional perfusion in the kidney donor: A porcine preclinical study by Kerforne, Thomas, Allain, Geraldine, Giraud, Sebastien, Bon, Delphine, Ameteau, Virginie, Couturier, Pierre, Hebrard, William, Danion, Jerome, Goujon, Jean‐Michel, Thuillier, Raphael, Hauet, Thierry, Barrou, Benoit, Jayle, Christophe

“…Kidneys from donation after circulatory death (DCD) are highly sensitive to ischemia‐reperfusion injury and thus require careful reconditioning, such as…”
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Rapid or Slow Time to Brain Death? Impact on Kidney Graft Injuries in an Allotransplantation Porcine Model by Kerforne, Thomas, Giraud, Sébastien, Danion, Jérôme, Thuillier, Raphael, Couturier, Pierre, Hebrard, William, Mimoz, Olivier, Hauet, Thierry

“…The use of donors deceased after brain death (DBD) with extended criteria in response to the shortage of grafts leads to the removal of more fragile kidneys…”
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